SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kbe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 3kbe SUPEROXIDE DISMUTASE
[CU-ZN]
(Caenorhabditis
elegans) 		3 / 3 ALA A 152
VAL A   7
TRP A  18
 None
 0.96A 1grmA-3kbeA:
undetectable		 1grmA-3kbeA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 3kbe SUPEROXIDE DISMUTASE
[CU-ZN]
(Caenorhabditis
elegans) 		3 / 3 ALA A 152
VAL A   7
TRP A  18
 None
 0.96A 1grmB-3kbeA:
undetectable		 1grmB-3kbeA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 3kbe SUPEROXIDE DISMUTASE
[CU-ZN]
(Caenorhabditis
elegans) 		5 / 12 ILE A  17
ILE A  96
PHE A  44
VAL A  13
LEU A  37
 None
 1.00A 1qhsA-3kbeA:
undetectable		 1qhsA-3kbeA:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3kbe SUPEROXIDE DISMUTASE
[CU-ZN]
(Caenorhabditis
elegans) 		5 / 12 ILE A  17
ILE A  96
PHE A  44
VAL A  13
LEU A  37
 None
 0.88A 1qhyA-3kbeA:
undetectable		 1qhyA-3kbeA:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 3kbe SUPEROXIDE DISMUTASE
[CU-ZN]
(Caenorhabditis
elegans) 		4 / 8 ILE A  96
ILE A  30
ARG A 114
ILE A  34
 None
 0.66A 2nniA-3kbeA:
undetectable		 2nniA-3kbeA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 3kbe SUPEROXIDE DISMUTASE
[CU-ZN]
(Caenorhabditis
elegans) 		4 / 6 LEU A  83
HIS A  62
HIS A  47
HIS A 119
 None
 0.92A 2ow9A-3kbeA:
undetectable		 2ow9A-3kbeA:
20.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3kbe SUPEROXIDE DISMUTASE
[CU-ZN]
(Caenorhabditis
elegans) 		4 / 4 HIS A  45
HIS A  47
HIS A  62
HIS A 119
 None
 0.68A 2wkoA-3kbeA:
20.0		 2wkoA-3kbeA:
55.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3kbe SUPEROXIDE DISMUTASE
[CU-ZN]
(Caenorhabditis
elegans) 		5 / 5 HIS A  45
HIS A  47
HIS A  62
VAL A 117
HIS A 119
 None
 0.62A 2wkoF-3kbeA:
20.0		 2wkoF-3kbeA:
55.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 3kbe SUPEROXIDE DISMUTASE
[CU-ZN]
(Caenorhabditis
elegans) 		4 / 7 GLY A 121
ALA A 146
ALA A 144
VAL A  13
 None
 0.77A 3a2qA-3kbeA:
undetectable		 3a2qA-3kbeA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 3kbe SUPEROXIDE DISMUTASE
[CU-ZN]
(Caenorhabditis
elegans) 		5 / 9 LEU A  98
ILE A  34
LEU A  37
ILE A  17
GLY A  43
 None
 0.99A 4kukA-3kbeA:
undetectable		 4kukA-3kbeA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 3kbe SUPEROXIDE DISMUTASE
[CU-ZN]
(Caenorhabditis
elegans) 		5 / 12 ALA A 147
GLY A 149
GLY A  55
SER A  52
GLY A  15
 None
 0.97A 5gwxA-3kbeA:
undetectable		 5gwxA-3kbeA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3kbe SUPEROXIDE DISMUTASE
[CU-ZN]
(Caenorhabditis
elegans) 		5 / 12 ILE A 151
ALA A   4
ILE A  17
ALA A   6
MET A 116
 None
 1.02A 5n0tB-3kbeA:
undetectable		 5n0tB-3kbeA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 3kbe SUPEROXIDE DISMUTASE
[CU-ZN]
(Caenorhabditis
elegans) 		4 / 4 HIS A  45
HIS A 119
HIS A  47
HIS A  62
 None
 1.17A 5zrdC-3kbeA:
undetectable		 5zrdC-3kbeA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 3kbe SUPEROXIDE DISMUTASE
[CU-ZN]
(Caenorhabditis
elegans) 		4 / 4 HIS A  45
HIS A 119
HIS A  47
HIS A  62
 None
 1.14A 5zrdD-3kbeA:
undetectable		 5zrdD-3kbeA:
17.04