SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kbq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 3kbq PROTEIN TA0487
(Thermoplasma
acidophilum) 		4 / 5 GLY A  26
LEU A  29
THR A  30
VAL A   5
 None
 0.79A 1ekjF-3kbqA:
2.5
1ekjG-3kbqA:
1.3		 1ekjF-3kbqA:
21.88
1ekjG-3kbqA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_A_SAMA301_0
(RRNA
METHYLTRANSFERASE)		 3kbq PROTEIN TA0487
(Thermoplasma
acidophilum) 		5 / 11 GLY A  50
GLY A  80
SER A  65
ALA A  52
ALA A  56
 None
 1.02A 1x7pA-3kbqA:
2.7
1x7pB-3kbqA:
2.6		 1x7pA-3kbqA:
23.16
1x7pB-3kbqA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 3kbq PROTEIN TA0487
(Thermoplasma
acidophilum) 		4 / 6 ILE A  25
TYR A  34
MET A 161
ILE A 145
 None
 1.16A 3eteA-3kbqA:
3.5
3eteE-3kbqA:
3.5		 3eteA-3kbqA:
17.37
3eteE-3kbqA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 3kbq PROTEIN TA0487
(Thermoplasma
acidophilum) 		4 / 5 ILE A  25
TYR A  34
MET A 161
ILE A 145
 None
 1.16A 3eteB-3kbqA:
3.5
3eteC-3kbqA:
3.5		 3eteB-3kbqA:
17.37
3eteC-3kbqA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 3kbq PROTEIN TA0487
(Thermoplasma
acidophilum) 		4 / 7 MET A 161
ILE A 145
ILE A  25
TYR A  34
 None
 1.16A 3eteD-3kbqA:
3.1
3eteF-3kbqA:
3.5		 3eteD-3kbqA:
17.37
3eteF-3kbqA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3kbq PROTEIN TA0487
(Thermoplasma
acidophilum) 		5 / 12 ILE A  49
THR A  77
VAL A  42
ASN A  21
SER A  65
 None
 1.17A 3kpdB-3kbqA:
undetectable		 3kpdB-3kbqA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3kbq PROTEIN TA0487
(Thermoplasma
acidophilum) 		4 / 5 ASP A  44
VAL A   8
GLY A  67
ASP A  75
 None
 1.46A 3w9tA-3kbqA:
undetectable		 3w9tA-3kbqA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 3kbq PROTEIN TA0487
(Thermoplasma
acidophilum) 		4 / 5 ASP A  44
VAL A   8
GLY A  67
ASP A  75
 None
 1.46A 3w9tB-3kbqA:
undetectable		 3w9tB-3kbqA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3kbq PROTEIN TA0487
(Thermoplasma
acidophilum) 		4 / 5 ASP A  44
VAL A   8
GLY A  67
ASP A  75
 None
 1.45A 3w9tC-3kbqA:
undetectable		 3w9tC-3kbqA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 3kbq PROTEIN TA0487
(Thermoplasma
acidophilum) 		4 / 5 ASP A  44
VAL A   8
GLY A  67
ASP A  75
 None
 1.47A 3w9tD-3kbqA:
undetectable		 3w9tD-3kbqA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 3kbq PROTEIN TA0487
(Thermoplasma
acidophilum) 		4 / 5 ASP A  44
VAL A   8
GLY A  67
ASP A  75
 None
 1.46A 3w9tE-3kbqA:
undetectable		 3w9tE-3kbqA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 3kbq PROTEIN TA0487
(Thermoplasma
acidophilum) 		4 / 5 ASP A  44
VAL A   8
GLY A  67
ASP A  75
 None
 1.46A 3w9tF-3kbqA:
undetectable		 3w9tF-3kbqA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 3kbq PROTEIN TA0487
(Thermoplasma
acidophilum) 		4 / 5 ASP A  44
VAL A   8
GLY A  67
ASP A  75
 None
 1.45A 3w9tG-3kbqA:
undetectable		 3w9tG-3kbqA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_B_SAMB601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 3kbq PROTEIN TA0487
(Thermoplasma
acidophilum) 		5 / 12 ASN A  19
GLY A  67
GLY A 149
MET A 154
PHE A  53
 None
 1.02A 4obwB-3kbqA:
2.6		 4obwB-3kbqA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 3kbq PROTEIN TA0487
(Thermoplasma
acidophilum) 		4 / 7 GLY A  68
ASP A  75
GLY A 149
GLU A 153
 None
 0.93A 4z53A-3kbqA:
2.7
4z53B-3kbqA:
2.3		 4z53A-3kbqA:
13.70
4z53B-3kbqA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3kbq PROTEIN TA0487
(Thermoplasma
acidophilum) 		4 / 4 LEU A  69
GLY A  67
SER A  66
SER A  65
 None
 1.22A 5uunA-3kbqA:
undetectable		 5uunA-3kbqA:
21.09