SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kbr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_J_TACJ5888_1
(ELONGATION FACTOR
EF-TU)		 3kbr CYCLOHEXADIENYL
DEHYDRATASE
(Pseudomonas
aeruginosa) 		4 / 6 THR A  83
SER A 102
SER A  51
VAL A  64
 None
 1.14A 2hdnI-3kbrA:
undetectable
2hdnJ-3kbrA:
undetectable
2hdnL-3kbrA:
undetectable		 2hdnI-3kbrA:
10.50
2hdnJ-3kbrA:
20.89
2hdnL-3kbrA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_L_TACL6888_1
(ELONGATION FACTOR
EF-TU)		 3kbr CYCLOHEXADIENYL
DEHYDRATASE
(Pseudomonas
aeruginosa) 		4 / 6 SER A  51
VAL A  64
THR A  83
SER A 102
 None
 1.17A 2hdnJ-3kbrA:
undetectable
2hdnK-3kbrA:
undetectable
2hdnL-3kbrA:
undetectable		 2hdnJ-3kbrA:
20.89
2hdnK-3kbrA:
10.50
2hdnL-3kbrA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 3kbr CYCLOHEXADIENYL
DEHYDRATASE
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 200
THR A 126
ALA A 199
PRO A 214
 None
None
None
FMT  A 265 (-4.1A)
 1.38A 2ql8A-3kbrA:
undetectable
2ql8B-3kbrA:
undetectable		 2ql8A-3kbrA:
20.50
2ql8B-3kbrA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 3kbr CYCLOHEXADIENYL
DEHYDRATASE
(Pseudomonas
aeruginosa) 		4 / 6 ILE A  99
ARG A  29
LEU A 227
LEU A  39
 None
 0.99A 2rlfA-3kbrA:
undetectable
2rlfD-3kbrA:
undetectable		 2rlfA-3kbrA:
11.84
2rlfD-3kbrA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		 3kbr CYCLOHEXADIENYL
DEHYDRATASE
(Pseudomonas
aeruginosa) 		4 / 8 MET A  66
ALA A  67
LEU A  70
ILE A 106
 None
 0.39A 3cldB-3kbrA:
undetectable		 3cldB-3kbrA:
23.21