SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kby'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 3kby PUTATIVE
UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		3 / 3 LEU A  94
LEU A  90
SER A  89
 None
 0.58A 1tlmA-3kbyA:
undetectable		 1tlmA-3kbyA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 3kby PUTATIVE
UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		3 / 3 LEU A  97
LEU A  94
SER A  91
 None
 0.65A 1tlmA-3kbyA:
undetectable		 1tlmA-3kbyA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CWK_A_REAA300_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 3kby PUTATIVE
UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 LEU A  56
ALA A  52
ALA A 101
VAL A 107
THR A 105
 None
 1.11A 3cwkA-3kbyA:
undetectable		 3cwkA-3kbyA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3kby PUTATIVE
UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		3 / 3 LEU A  94
PRO A  93
LEU A  97
 None
 0.54A 3hcrA-3kbyA:
undetectable		 3hcrA-3kbyA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)		 3kby PUTATIVE
UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 11 SER A 113
PHE A 110
ILE A 109
GLU A 103
ASP A 106
 None
 1.08A 3ko0C-3kbyA:
undetectable
3ko0D-3kbyA:
undetectable
3ko0E-3kbyA:
undetectable
3ko0F-3kbyA:
undetectable		 3ko0C-3kbyA:
21.13
3ko0D-3kbyA:
21.13
3ko0E-3kbyA:
21.13
3ko0F-3kbyA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 3kby PUTATIVE
UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 11 GLU A 103
ASP A 106
SER A 113
PHE A 110
ILE A 109
 None
 1.01A 3ko0E-3kbyA:
undetectable
3ko0F-3kbyA:
undetectable
3ko0G-3kbyA:
undetectable
3ko0H-3kbyA:
undetectable		 3ko0E-3kbyA:
21.13
3ko0F-3kbyA:
21.13
3ko0G-3kbyA:
21.13
3ko0H-3kbyA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_G_TFPG202_1
(PROTEIN S100-A4)		 3kby PUTATIVE
UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 10 SER A 113
PHE A 110
ILE A 109
GLU A 103
ASP A 106
 None
 1.11A 3ko0E-3kbyA:
undetectable
3ko0F-3kbyA:
undetectable
3ko0G-3kbyA:
undetectable
3ko0H-3kbyA:
undetectable		 3ko0E-3kbyA:
21.13
3ko0F-3kbyA:
21.13
3ko0G-3kbyA:
21.13
3ko0H-3kbyA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 3kby PUTATIVE
UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 SER A 113
PHE A 110
ILE A 109
GLU A 103
ASP A 106
 None
 1.06A 3ko0K-3kbyA:
undetectable
3ko0L-3kbyA:
undetectable
3ko0S-3kbyA:
undetectable
3ko0T-3kbyA:
undetectable		 3ko0K-3kbyA:
21.13
3ko0L-3kbyA:
21.13
3ko0S-3kbyA:
21.13
3ko0T-3kbyA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 3kby PUTATIVE
UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 SER A 113
PHE A 110
ILE A 109
GLU A 103
ASP A 106
 None
 1.07A 3ko0M-3kbyA:
undetectable
3ko0N-3kbyA:
undetectable
3ko0O-3kbyA:
undetectable
3ko0P-3kbyA:
undetectable		 3ko0M-3kbyA:
21.13
3ko0N-3kbyA:
21.13
3ko0O-3kbyA:
21.13
3ko0P-3kbyA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR202_1
(PROTEIN S100-A4)		 3kby PUTATIVE
UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 11 GLU A 103
ASP A 106
SER A 113
PHE A 110
ILE A 109
 None
 1.08A 3ko0Q-3kbyA:
undetectable
3ko0R-3kbyA:
undetectable
3ko0S-3kbyA:
undetectable
3ko0T-3kbyA:
undetectable		 3ko0Q-3kbyA:
21.13
3ko0R-3kbyA:
21.13
3ko0S-3kbyA:
21.13
3ko0T-3kbyA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3kby PUTATIVE
UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 PRO A  73
TRP A  76
LEU A  56
TYR A 133
PHE A 130
 None
 1.26A 4a79A-3kbyA:
undetectable		 4a79A-3kbyA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3kby PUTATIVE
UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 PRO A  73
TRP A  76
LEU A  56
TYR A 133
PHE A 130
 None
 1.26A 4a79B-3kbyA:
undetectable		 4a79B-3kbyA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3kby PUTATIVE
UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		3 / 3 VAL A  25
ALA A 125
PHE A  23
 None
 0.93A 4w5nA-3kbyA:
undetectable		 4w5nA-3kbyA:
10.13