SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kcc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3kcc CATABOLITE GENE
ACTIVATOR
(Escherichia
coli) 		4 / 4 ILE A 172
GLN A 145
ILE A 203
LEU A 137
 None
 1.08A 3dzyD-3kccA:
undetectable		 3dzyD-3kccA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 3kcc CATABOLITE GENE
ACTIVATOR
(Escherichia
coli) 		5 / 10 THR A 182
GLY A 184
GLU A 181
LEU A 187
ILE A 143
 None
None
CMP  A 303 ( 4.4A)
None
None
 1.11A 3kvrA-3kccA:
undetectable		 3kvrA-3kccA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3kcc CATABOLITE GENE
ACTIVATOR
(Escherichia
coli) 		5 / 10 THR A 182
GLY A 184
GLU A 181
LEU A 187
ILE A 143
 None
None
CMP  A 303 ( 4.4A)
None
None
 1.15A 3kvrB-3kccA:
undetectable		 3kvrB-3kccA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 3kcc CATABOLITE GENE
ACTIVATOR
(Escherichia
coli) 		5 / 9 THR A 182
GLY A 184
GLU A 181
LEU A 187
ILE A 143
 None
None
CMP  A 303 ( 4.4A)
None
None
 1.13A 3nbqA-3kccA:
undetectable		 3nbqA-3kccA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA505_0
(RNA POLYMERASE
3D-POL)		 3kcc CATABOLITE GENE
ACTIVATOR
(Escherichia
coli) 		3 / 3 CYH A  92
ASN A  65
LYS A  89
 None
 1.32A 4k50A-3kccA:
undetectable		 4k50A-3kccA:
19.48