SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kcm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X45_A_HSMA1160_1 (ALLERGEN ARG R 1)	3kcm	THIOREDOXIN FAMILY PROTEIN (Geobacter metallireducens)	4 / 6	SER A 92 VAL A 131 ASP A 94 TRP A 63	None None None SO4 A 1 (-3.9A)	1.26A	2x45A-3kcmA: undetectable	2x45A-3kcmA: 19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X45_B_HSMB1160_1 (ALLERGEN ARG R 1)	3kcm	THIOREDOXIN FAMILY PROTEIN (Geobacter metallireducens)	4 / 7	SER A 92 VAL A 131 ASP A 94 TRP A 63	None None None SO4 A 1 (-3.9A)	1.26A	2x45B-3kcmA: undetectable	2x45B-3kcmA: 19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X45_C_HSMC1160_1 (ALLERGEN ARG R 1)	3kcm	THIOREDOXIN FAMILY PROTEIN (Geobacter metallireducens)	4 / 7	SER A 92 VAL A 131 ASP A 94 TRP A 63	None None None SO4 A 1 (-3.9A)	1.25A	2x45C-3kcmA: undetectable	2x45C-3kcmA: 19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZPH_A_PRLA501_0 (ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1)	3kcm	THIOREDOXIN FAMILY PROTEIN (Geobacter metallireducens)	4 / 7	TRP A 153 LEU A 77 SER A 73 GLU A 70	None	1.02A	4zphA-3kcmA: undetectable 4zphB-3kcmA: undetectable	4zphA-3kcmA: 19.27 4zphB-3kcmA: 16.67

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2X45_A_HSMA1160_1","ALLERGEN ARG R 1","3kcm","THIOREDOXIN FAMILY PROTEIN","Geobacter metallireducens",4,"SER A  92;VAL A 131;ASP A  94;TRP A  63","None;None;None;SO4 A   1 (-3.9A)","1.26A","2x45A-3kcmA:undetectable","2x45A-3kcmA:19.88"],["2X45_B_HSMB1160_1","ALLERGEN ARG R 1","3kcm","THIOREDOXIN FAMILY PROTEIN","Geobacter metallireducens",4,"SER A  92;VAL A 131;ASP A  94;TRP A  63","None;None;None;SO4 A   1 (-3.9A)","1.26A","2x45B-3kcmA:undetectable","2x45B-3kcmA:19.88"],["2X45_C_HSMC1160_1","ALLERGEN ARG R 1","3kcm","THIOREDOXIN FAMILY PROTEIN","Geobacter metallireducens",4,"SER A  92;VAL A 131;ASP A  94;TRP A  63","None;None;None;SO4 A   1 (-3.9A)","1.25A","2x45C-3kcmA:undetectable","2x45C-3kcmA:19.88"],["4ZPH_A_PRLA501_0","ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR;ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1","3kcm","THIOREDOXIN FAMILY PROTEIN","Geobacter metallireducens",4,"TRP A 153;LEU A  77;SER A  73;GLU A  70","None","1.02A","4zphA-3kcmA:undetectable;4zphB-3kcmA:undetectable","4zphA-3kcmA:19.27;4zphB-3kcmA:16.67"]]