SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kcn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3kcn ADENYLATE CYCLASE
HOMOLOG
(Rhodopirellula
baltica) 		5 / 12 LEU A  11
LEU A  82
ILE A 115
ILE A   9
PHE A 103
 None
 0.90A 4a79A-3kcnA:
undetectable		 4a79A-3kcnA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3kcn ADENYLATE CYCLASE
HOMOLOG
(Rhodopirellula
baltica) 		5 / 12 LEU A  11
LEU A  82
ILE A 115
ILE A   9
PHE A 103
 None
 0.93A 4a79B-3kcnA:
undetectable		 4a79B-3kcnA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_A_RGZA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3kcn ADENYLATE CYCLASE
HOMOLOG
(Rhodopirellula
baltica) 		5 / 11 LEU A  11
LEU A  82
ILE A 115
ILE A   9
PHE A 103
 None
 0.87A 4a7aA-3kcnA:
undetectable		 4a7aA-3kcnA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3kcn ADENYLATE CYCLASE
HOMOLOG
(Rhodopirellula
baltica) 		5 / 12 LEU A  11
LEU A  82
ILE A 115
ILE A   9
PHE A 103
 None
 0.85A 4a7aB-3kcnA:
undetectable		 4a7aB-3kcnA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 3kcn ADENYLATE CYCLASE
HOMOLOG
(Rhodopirellula
baltica) 		4 / 4 VAL A  68
GLU A  67
GLY A  38
LEU A  42
 None
 1.14A 5g5gC-3kcnA:
undetectable		 5g5gC-3kcnA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 3kcn ADENYLATE CYCLASE
HOMOLOG
(Rhodopirellula
baltica) 		3 / 3 LYS A 108
LEU A  22
ASP A  13
 None
 0.91A 5zv2A-3kcnA:
undetectable		 5zv2A-3kcnA:
19.46