SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kcq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3kcq PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Anaplasma
phagocytophilum) 		4 / 7 TYR A 176
VAL A   9
GLY A   8
VAL A  32
 None
 0.94A 1t88A-3kcqA:
undetectable		 1t88A-3kcqA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)		 3kcq PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Anaplasma
phagocytophilum) 		5 / 12 SER A  30
THR A  27
ALA A  20
VAL A 180
VAL A   9
 None
 1.26A 2nniA-3kcqA:
undetectable		 2nniA-3kcqA:
19.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3kcq PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Anaplasma
phagocytophilum) 		5 / 12 ILE A  90
LEU A  91
ASN A 105
PRO A 108
VAL A 138
 None
 0.88A 3dcjA-3kcqA:
26.8
3dcjB-3kcqA:
27.5		 3dcjA-3kcqA:
31.58
3dcjB-3kcqA:
31.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OPE_A_SAMA7_0
(PROBABLE
HISTONE-LYSINE
N-METHYLTRANSFERASE
ASH1L)		 3kcq PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Anaplasma
phagocytophilum) 		5 / 12 GLY A  86
ASN A  17
GLN A 120
CYH A 133
ILE A 168
 GOL  A 801 ( 4.4A)
GOL  A 801 (-3.9A)
None
None
None
 1.23A 3opeA-3kcqA:
undetectable		 3opeA-3kcqA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 3kcq PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Anaplasma
phagocytophilum) 		5 / 10 ILE A 103
TRP A  99
LEU A  91
PHE A  95
ILE A  55
 None
 1.05A 5hw8C-3kcqA:
undetectable
5hw8H-3kcqA:
undetectable		 5hw8C-3kcqA:
17.21
5hw8H-3kcqA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 3kcq PHOSPHORIBOSYLGLYCIN
AMIDE
FORMYLTRANSFERASE
(Anaplasma
phagocytophilum) 		5 / 10 ILE A  11
VAL A  79
ILE A  70
LEU A  74
LEU A  47
 None
 1.18A 5ienB-3kcqA:
undetectable		 5ienB-3kcqA:
20.91