SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kd3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 3kd3 PHOSPHOSERINE
PHOSPHOHYDROLASE-LIK
E PROTEIN
(Francisella
tularensis) 		3 / 3 ASN A 143
PHE A  50
VAL A 126
 None
 0.83A 1kijA-3kd3A:
undetectable		 1kijA-3kd3A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 3kd3 PHOSPHOSERINE
PHOSPHOHYDROLASE-LIK
E PROTEIN
(Francisella
tularensis) 		4 / 6 LEU A  58
LEU A  54
SER A  53
THR A  40
 None
 1.27A 1tyrA-3kd3A:
undetectable		 1tyrA-3kd3A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3kd3 PHOSPHOSERINE
PHOSPHOHYDROLASE-LIK
E PROTEIN
(Francisella
tularensis) 		4 / 7 ILE A 100
PHE A 153
LYS A 149
GLY A 103
 None
 1.11A 3em0B-3kd3A:
undetectable		 3em0B-3kd3A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_C_ACHC323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 3kd3 PHOSPHOSERINE
PHOSPHOHYDROLASE-LIK
E PROTEIN
(Francisella
tularensis) 		4 / 8 GLU A  23
TYR A  75
LEU A  79
PHE A  71
 None
 1.05A 3rqwC-3kd3A:
undetectable
3rqwD-3kd3A:
undetectable		 3rqwC-3kd3A:
22.29
3rqwD-3kd3A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA504_1
(CYTOCHROME P450 2B4)		 3kd3 PHOSPHOSERINE
PHOSPHOHYDROLASE-LIK
E PROTEIN
(Francisella
tularensis) 		5 / 9 LEU A  54
LEU A 139
ILE A 123
GLU A 127
PHE A  50
 None
 1.34A 3tmzA-3kd3A:
undetectable		 3tmzA-3kd3A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3kd3 PHOSPHOSERINE
PHOSPHOHYDROLASE-LIK
E PROTEIN
(Francisella
tularensis) 		4 / 8 THR A 128
PRO A  63
ILE A  68
PRO A 111
 None
 0.74A 5g48A-3kd3A:
undetectable		 5g48A-3kd3A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 3kd3 PHOSPHOSERINE
PHOSPHOHYDROLASE-LIK
E PROTEIN
(Francisella
tularensis) 		3 / 3 GLY A  46
GLN A 175
LYS A 196
 None
 0.55A 5imsB-3kd3A:
3.3		 5imsB-3kd3A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MSD_A_BEZA1202_0
(CARBOXYLIC ACID
REDUCTASE)		 3kd3 PHOSPHOSERINE
PHOSPHOHYDROLASE-LIK
E PROTEIN
(Francisella
tularensis) 		4 / 5 ILE A 123
PHE A   8
SER A 108
ALA A 113
 None
 1.01A 5msdA-3kd3A:
2.2		 5msdA-3kd3A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3kd3 PHOSPHOSERINE
PHOSPHOHYDROLASE-LIK
E PROTEIN
(Francisella
tularensis) 		3 / 3 VAL A 197
TYR A 171
GLN A  45
 None
 0.65A 5qgkA-3kd3A:
undetectable		 5qgkA-3kd3A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3kd3 PHOSPHOSERINE
PHOSPHOHYDROLASE-LIK
E PROTEIN
(Francisella
tularensis) 		3 / 3 VAL A 197
TYR A 171
GLN A  45
 None
 0.65A 5qgrA-3kd3A:
undetectable		 5qgrA-3kd3A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3kd3 PHOSPHOSERINE
PHOSPHOHYDROLASE-LIK
E PROTEIN
(Francisella
tularensis) 		3 / 3 VAL A 197
TYR A 171
GLN A  45
 None
 0.70A 5qgtA-3kd3A:
undetectable		 5qgtA-3kd3A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 3kd3 PHOSPHOSERINE
PHOSPHOHYDROLASE-LIK
E PROTEIN
(Francisella
tularensis) 		4 / 8 LEU A 211
ILE A  98
PHE A 101
LEU A 176
 None
 0.74A 5y7pC-3kd3A:
undetectable		 5y7pC-3kd3A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 3kd3 PHOSPHOSERINE
PHOSPHOHYDROLASE-LIK
E PROTEIN
(Francisella
tularensis) 		5 / 12 ALA A 166
MET A  44
ARG A 194
ASP A 173
LEU A 176
 None
MG  A 401 ( 4.6A)
None
MG  A 401 ( 4.9A)
None
 1.27A 6ie8A-3kd3A:
undetectable		 6ie8A-3kd3A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3kd3 PHOSPHOSERINE
PHOSPHOHYDROLASE-LIK
E PROTEIN
(Francisella
tularensis) 		4 / 4 ASP A   9
ILE A  21
PRO A  63
LEU A  18
 None
 1.49A 6mkeB-3kd3A:
undetectable		 6mkeB-3kd3A:
21.30