SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kdq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A51_C_VDYC6178_1 (VITAMIN D HYDROXYLASE)	3kdq	UNCHARACTERIZED CONSERVED PROTEIN (Corynebacterium diphtheriae)	5 / 12	THR A 117 MET A 118 ILE A 123 LEU A 100 LEU A 92	None	1.16A	3a51C-3kdqA: 2.1	3a51C-3kdqA: 19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L3G_F_ACTF401_0 (METHYLAMINE DEHYDROGENASE HEAVY CHAIN)	3kdq	UNCHARACTERIZED CONSERVED PROTEIN (Corynebacterium diphtheriae)	3 / 3	ARG A 16 LEU A 20 GLU A 19	None	0.75A	4l3gF-3kdqA: undetectable	4l3gF-3kdqA: 18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MA3_L_ACTL301_0 (C2095 HEAVY CHAIN C2095 LIGHT CHAIN)	3kdq	UNCHARACTERIZED CONSERVED PROTEIN (Corynebacterium diphtheriae)	3 / 3	PRO A 36 ASN A 39 HIS A 41	None	1.03A	4ma3H-3kdqA: undetectable 4ma3L-3kdqA: undetectable	4ma3H-3kdqA: 19.21 4ma3L-3kdqA: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NC3_A_ERMA1202_2 (CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 2B AND E. COLI SOLUBLE CYTOCHROME B562)	3kdq	UNCHARACTERIZED CONSERVED PROTEIN (Corynebacterium diphtheriae)	4 / 6	LEU A 76 GLN A 151 LEU A 150 GLU A 149	None	0.85A	4nc3A-3kdqA: 3.9	4nc3A-3kdqA: 18.88

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3A51_C_VDYC6178_1","VITAMIN D HYDROXYLASE","3kdq","UNCHARACTERIZED CONSERVED PROTEIN","Corynebacterium diphtheriae",5,"THR A 117;MET A 118;ILE A 123;LEU A 100;LEU A  92","None","1.16A","3a51C-3kdqA:2.1","3a51C-3kdqA:19.20"],["4L3G_F_ACTF401_0","METHYLAMINE DEHYDROGENASE HEAVY CHAIN","3kdq","UNCHARACTERIZED CONSERVED PROTEIN","Corynebacterium diphtheriae",3,"ARG A  16;LEU A  20;GLU A  19","None","0.75A","4l3gF-3kdqA:undetectable","4l3gF-3kdqA:18.04"],["4MA3_L_ACTL301_0","C2095 HEAVY CHAIN;C2095 LIGHT CHAIN","3kdq","UNCHARACTERIZED CONSERVED PROTEIN","Corynebacterium diphtheriae",3,"PRO A  36;ASN A  39;HIS A  41","None","1.03A","4ma3H-3kdqA:undetectable;4ma3L-3kdqA:undetectable","4ma3H-3kdqA:19.21;4ma3L-3kdqA:18.75"],["4NC3_A_ERMA1202_2","CHIMERA PROTEIN OF HUMAN 5-HYDROXYTRYPTAMINE RECEPTOR 2B AND E. COLI SOLUBLE CYTOCHROME B562","3kdq","UNCHARACTERIZED CONSERVED PROTEIN","Corynebacterium diphtheriae",4,"LEU A  76;GLN A 151;LEU A 150;GLU A 149","None","0.85A","4nc3A-3kdqA:3.9","4nc3A-3kdqA:18.88"]]