SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kdr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D4F_C_ADNC603_2 (S-ADENOSYLHOMOCYSTEI NE HYDROLASE)	3kdr	HK97 FAMILY PHAGE PORTAL PROTEIN (Corynebacterium diphtheriae)	4 / 5	THR A 73 GLU A 299 THR A 295 LEU A 331	None	1.34A	1d4fC-3kdrA: undetectable	1d4fC-3kdrA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TKQ_B_DVAB6_0 (GRAMICIDIN A)	3kdr	HK97 FAMILY PHAGE PORTAL PROTEIN (Corynebacterium diphtheriae)	3 / 3	ALA A 152 VAL A 148 TRP A 139	None	0.80A	1tkqB-3kdrA: undetectable	1tkqB-3kdrA: 5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L9Q_A_9TPA601_1 (SERUM ALBUMIN)	3kdr	HK97 FAMILY PHAGE PORTAL PROTEIN (Corynebacterium diphtheriae)	5 / 12	LEU A 66 ARG A 63 ILE A 164 HIS A 165 GLY A 114	None PO4 A 1 ( 4.9A) None None None	1.35A	4l9qA-3kdrA: 2.9	4l9qA-3kdrA: 19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RN6_A_15UA301_1 (THROMBIN HEAVY CHAIN)	3kdr	HK97 FAMILY PHAGE PORTAL PROTEIN (Corynebacterium diphtheriae)	5 / 10	LEU A 136 LEU A 301 ALA A 304 ALA A 107 GLY A 114	None	1.31A	4rn6A-3kdrA: undetectable	4rn6A-3kdrA: 20.74

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1D4F_C_ADNC603_2","S-ADENOSYLHOMOCYSTEINE HYDROLASE","3kdr","HK97 FAMILY PHAGE PORTAL PROTEIN","Corynebacterium diphtheriae",4,"THR A  73;GLU A 299;THR A 295;LEU A 331","None","1.34A","1d4fC-3kdrA:undetectable","1d4fC-3kdrA:21.95"],["1TKQ_B_DVAB6_0","GRAMICIDIN A","3kdr","HK97 FAMILY PHAGE PORTAL PROTEIN","Corynebacterium diphtheriae",3,"ALA A 152;VAL A 148;TRP A 139","None","0.80A","1tkqB-3kdrA:undetectable","1tkqB-3kdrA:5.52"],["4L9Q_A_9TPA601_1","SERUM ALBUMIN","3kdr","HK97 FAMILY PHAGE PORTAL PROTEIN","Corynebacterium diphtheriae",5,"LEU A  66;ARG A  63;ILE A 164;HIS A 165;GLY A 114","None;PO4 A   1 ( 4.9A);None;None;None","1.35A","4l9qA-3kdrA:2.9","4l9qA-3kdrA:19.22"],["4RN6_A_15UA301_1","THROMBIN HEAVY CHAIN","3kdr","HK97 FAMILY PHAGE PORTAL PROTEIN","Corynebacterium diphtheriae",5,"LEU A 136;LEU A 301;ALA A 304;ALA A 107;GLY A 114","None","1.31A","4rn6A-3kdrA:undetectable","4rn6A-3kdrA:20.74"]]