SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kdw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X2N_A_X2NA1480_1 (LANOSTEROL 14-ALPHA-DEMETHYLASE)	3kdw	PUTATIVE SUGAR BINDING PROTEIN (Bacteroides vulgatus)	5 / 12	TYR A 67 PRO A 116 ALA A 117 ALA A 176 ALA A 173	None	1.16A	2x2nA-3kdwA: undetectable	2x2nA-3kdwA: 18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X2N_B_X2NB1479_1 (LANOSTEROL 14-ALPHA-DEMETHYLASE)	3kdw	PUTATIVE SUGAR BINDING PROTEIN (Bacteroides vulgatus)	6 / 12	PHE A 115 TYR A 67 PRO A 116 ALA A 117 ALA A 176 ALA A 173	None	1.37A	2x2nB-3kdwA: undetectable	2x2nB-3kdwA: 18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X2N_C_X2NC1479_1 (LANOSTEROL 14-ALPHA-DEMETHYLASE)	3kdw	PUTATIVE SUGAR BINDING PROTEIN (Bacteroides vulgatus)	5 / 12	PHE A 115 TYR A 67 PRO A 116 ALA A 176 ALA A 173	None	1.25A	2x2nC-3kdwA: undetectable	2x2nC-3kdwA: 18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z84_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	3kdw	PUTATIVE SUGAR BINDING PROTEIN (Bacteroides vulgatus)	3 / 3	TYR A 109 ARG A 110 THR A 111	None	1.02A	5z84J-3kdwA: undetectable	5z84J-3kdwA: 12.44

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2X2N_A_X2NA1480_1","LANOSTEROL 14-ALPHA-DEMETHYLASE","3kdw","PUTATIVE SUGAR BINDING PROTEIN","Bacteroides vulgatus",5,"TYR A  67;PRO A 116;ALA A 117;ALA A 176;ALA A 173","None","1.16A","2x2nA-3kdwA:undetectable","2x2nA-3kdwA:18.34"],["2X2N_B_X2NB1479_1","LANOSTEROL 14-ALPHA-DEMETHYLASE","3kdw","PUTATIVE SUGAR BINDING PROTEIN","Bacteroides vulgatus",6,"PHE A 115;TYR A  67;PRO A 116;ALA A 117;ALA A 176;ALA A 173","None","1.37A","2x2nB-3kdwA:undetectable","2x2nB-3kdwA:18.34"],["2X2N_C_X2NC1479_1","LANOSTEROL 14-ALPHA-DEMETHYLASE","3kdw","PUTATIVE SUGAR BINDING PROTEIN","Bacteroides vulgatus",5,"PHE A 115;TYR A  67;PRO A 116;ALA A 176;ALA A 173","None","1.25A","2x2nC-3kdwA:undetectable","2x2nC-3kdwA:18.34"],["5Z84_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","3kdw","PUTATIVE SUGAR BINDING PROTEIN","Bacteroides vulgatus",3,"TYR A 109;ARG A 110;THR A 111","None","1.02A","5z84J-3kdwA:undetectable","5z84J-3kdwA:12.44"]]