SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ke5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P5Z_B_AR3B304_1
(DEOXYCYTIDINE KINASE)
3ke5 HYPOTHETICAL
CYTOSOLIC PROTEIN

(Bacillus
cereus)
5 / 12 ILE A  55
GLU A 102
TYR A 158
ARG A 169
GLU A  58
None
1.35A 1p5zB-3ke5A:
undetectable
1p5zB-3ke5A:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P62_B_GEOB302_1
(DEOXYCYTIDINE KINASE)
3ke5 HYPOTHETICAL
CYTOSOLIC PROTEIN

(Bacillus
cereus)
5 / 11 ILE A  55
GLU A 102
TYR A 158
ARG A 169
GLU A  58
None
1.32A 1p62B-3ke5A:
0.0
1p62B-3ke5A:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BU8_A_TF4A1379_1
(PYRUVATE
DEHYDROGENASE KINASE
ISOENZYME 2)
3ke5 HYPOTHETICAL
CYTOSOLIC PROTEIN

(Bacillus
cereus)
4 / 8 LEU A  59
ILE A 121
ILE A  55
ILE A 166
None
0.81A 2bu8A-3ke5A:
2.3
2bu8A-3ke5A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_A_GEOA302_1
(DEOXYCYTIDINE KINASE)
3ke5 HYPOTHETICAL
CYTOSOLIC PROTEIN

(Bacillus
cereus)
5 / 12 ILE A  55
GLU A 102
TYR A 158
ARG A 169
GLU A  58
None
1.30A 2no0A-3ke5A:
undetectable
2no0A-3ke5A:
27.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NO0_B_GEOB302_1
(DEOXYCYTIDINE KINASE)
3ke5 HYPOTHETICAL
CYTOSOLIC PROTEIN

(Bacillus
cereus)
5 / 12 ILE A  55
GLU A 102
TYR A 158
ARG A 169
GLU A  58
None
1.29A 2no0B-3ke5A:
undetectable
2no0B-3ke5A:
27.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)
3ke5 HYPOTHETICAL
CYTOSOLIC PROTEIN

(Bacillus
cereus)
5 / 11 LEU A  66
VAL A  89
ILE A  33
LEU A  73
ASP A  72
None
1.06A 2q6hA-3ke5A:
undetectable
2q6hA-3ke5A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)
3ke5 HYPOTHETICAL
CYTOSOLIC PROTEIN

(Bacillus
cereus)
5 / 11 LEU A  66
VAL A  89
ILE A  33
LEU A  73
ASP A  72
None
1.05A 2q72A-3ke5A:
undetectable
2q72A-3ke5A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)
3ke5 HYPOTHETICAL
CYTOSOLIC PROTEIN

(Bacillus
cereus)
5 / 11 LEU A  66
VAL A  89
ILE A  33
LEU A  73
ASP A  72
None
1.07A 2qeiA-3ke5A:
1.7
2qeiA-3ke5A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VPP_A_GEOA1210_1
(DEOXYNUCLEOSIDE
KINASE)
3ke5 HYPOTHETICAL
CYTOSOLIC PROTEIN

(Bacillus
cereus)
5 / 12 ILE A  55
GLU A 102
TYR A 158
ARG A 169
GLU A  58
None
1.27A 2vppA-3ke5A:
undetectable
2vppA-3ke5A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VPP_B_GEOB1207_1
(DEOXYNUCLEOSIDE
KINASE)
3ke5 HYPOTHETICAL
CYTOSOLIC PROTEIN

(Bacillus
cereus)
5 / 12 ILE A  55
GLU A 102
TYR A 158
ARG A 169
GLU A  58
None
1.27A 2vppB-3ke5A:
undetectable
2vppB-3ke5A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_1
(DEOXYCYTIDINE KINASE)
3ke5 HYPOTHETICAL
CYTOSOLIC PROTEIN

(Bacillus
cereus)
5 / 12 ILE A  55
GLU A 102
TYR A 158
ARG A 169
GLU A  58
None
1.27A 2zi9A-3ke5A:
undetectable
2zi9A-3ke5A:
26.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_A_CL9A401_1
(DEOXYCYTIDINE KINASE)
3ke5 HYPOTHETICAL
CYTOSOLIC PROTEIN

(Bacillus
cereus)
5 / 12 ILE A  55
GLU A 102
TYR A 158
ARG A 169
GLU A  58
None
1.32A 2ziaA-3ke5A:
undetectable
2ziaA-3ke5A:
27.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)
3ke5 HYPOTHETICAL
CYTOSOLIC PROTEIN

(Bacillus
cereus)
4 / 7 VAL A 165
ILE A  96
TYR A  99
ILE A 100
None
0.83A 3hgxA-3ke5A:
undetectable
3hgxA-3ke5A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HP1_A_LLTA401_1
(DEOXYCYTIDINE KINASE)
3ke5 HYPOTHETICAL
CYTOSOLIC PROTEIN

(Bacillus
cereus)
5 / 12 GLU A 102
TYR A 158
ARG A 169
ALA A 168
GLU A  58
None
1.25A 3hp1A-3ke5A:
undetectable
3hp1A-3ke5A:
27.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
3ke5 HYPOTHETICAL
CYTOSOLIC PROTEIN

(Bacillus
cereus)
4 / 8 ILE A  55
GLU A  58
TYR A 158
LEU A 155
None
1.04A 3rqwI-3ke5A:
undetectable
3rqwJ-3ke5A:
undetectable
3rqwI-3ke5A:
20.81
3rqwJ-3ke5A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)
3ke5 HYPOTHETICAL
CYTOSOLIC PROTEIN

(Bacillus
cereus)
4 / 6 PHE A 160
ALA A 163
ALA A 103
PRO A 104
None
1.03A 4dtzA-3ke5A:
undetectable
4dtzA-3ke5A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)
3ke5 HYPOTHETICAL
CYTOSOLIC PROTEIN

(Bacillus
cereus)
4 / 5 ARG A 133
VAL A 152
LEU A 155
SER A 156
None
None
None
MG  A 204 ( 4.3A)
1.36A 4e1gA-3ke5A:
undetectable
4e1gA-3ke5A:
18.06