SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ke6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_1
(HIV-II PROTEASE)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 175
ALA A 176
ASP A 177
ILE A 323
GLY A 320
 None
 0.95A 1hshC-3ke6A:
undetectable		 1hshC-3ke6A:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 5 LEU A 425
GLY A 470
ALA A 430
ILE A 428
 None
 0.80A 2aohB-3ke6A:
undetectable		 2aohB-3ke6A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		5 / 9 LEU A 324
ILE A 368
ALA A 179
GLY A 265
LEU A 207
 None
 1.01A 2v0mB-3ke6A:
undetectable		 2v0mB-3ke6A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 6 LEU A 205
ILE A 178
ILE A 352
LEU A 285
 None
 0.95A 2xkwB-3ke6A:
undetectable		 2xkwB-3ke6A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 175
ALA A 176
ASP A 177
GLY A 320
LEU A 267
 None
 0.71A 3ogpA-3ke6A:
undetectable		 3ogpA-3ke6A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_2
(FIV PROTEASE)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		6 / 9 GLY A 175
ALA A 176
ASP A 177
ILE A 178
GLY A 320
LEU A 267
 None
 1.34A 3ogpB-3ke6A:
undetectable		 3ogpB-3ke6A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 5 ASP A 211
VAL A 213
GLY A 214
ASP A 387
 MN  A   2 ( 2.5A)
MN  A 541 ( 4.7A)
None
MN  A   2 (-2.6A)
 0.86A 3w9tA-3ke6A:
undetectable		 3w9tA-3ke6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 5 ASP A 211
VAL A 213
GLY A 214
ASP A 388
 MN  A   2 ( 2.5A)
MN  A 541 ( 4.7A)
None
None
 1.08A 3w9tA-3ke6A:
undetectable		 3w9tA-3ke6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 5 ASP A 211
VAL A 213
GLY A 214
ASP A 387
 MN  A   2 ( 2.5A)
MN  A 541 ( 4.7A)
None
MN  A   2 (-2.6A)
 0.87A 3w9tB-3ke6A:
undetectable		 3w9tB-3ke6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 5 ASP A 211
VAL A 213
GLY A 214
ASP A 388
 MN  A   2 ( 2.5A)
MN  A 541 ( 4.7A)
None
None
 1.08A 3w9tB-3ke6A:
undetectable		 3w9tB-3ke6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 5 ASP A 211
VAL A 213
GLY A 214
ASP A 387
 MN  A   2 ( 2.5A)
MN  A 541 ( 4.7A)
None
MN  A   2 (-2.6A)
 0.86A 3w9tC-3ke6A:
undetectable		 3w9tC-3ke6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 5 ASP A 211
VAL A 213
GLY A 214
ASP A 388
 MN  A   2 ( 2.5A)
MN  A 541 ( 4.7A)
None
None
 1.09A 3w9tC-3ke6A:
undetectable		 3w9tC-3ke6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 5 ASP A 211
VAL A 213
GLY A 214
ASP A 387
 MN  A   2 ( 2.5A)
MN  A 541 ( 4.7A)
None
MN  A   2 (-2.6A)
 0.86A 3w9tD-3ke6A:
undetectable		 3w9tD-3ke6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 5 ASP A 211
VAL A 213
GLY A 214
ASP A 388
 MN  A   2 ( 2.5A)
MN  A 541 ( 4.7A)
None
None
 1.07A 3w9tD-3ke6A:
undetectable		 3w9tD-3ke6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 5 ASP A 211
VAL A 213
GLY A 214
ASP A 387
 MN  A   2 ( 2.5A)
MN  A 541 ( 4.7A)
None
MN  A   2 (-2.6A)
 0.86A 3w9tE-3ke6A:
undetectable		 3w9tE-3ke6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 5 ASP A 211
VAL A 213
GLY A 214
ASP A 388
 MN  A   2 ( 2.5A)
MN  A 541 ( 4.7A)
None
None
 1.07A 3w9tE-3ke6A:
undetectable		 3w9tE-3ke6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 5 ASP A 211
VAL A 213
GLY A 214
ASP A 387
 MN  A   2 ( 2.5A)
MN  A 541 ( 4.7A)
None
MN  A   2 (-2.6A)
 0.87A 3w9tF-3ke6A:
undetectable		 3w9tF-3ke6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 5 ASP A 211
VAL A 213
GLY A 214
ASP A 388
 MN  A   2 ( 2.5A)
MN  A 541 ( 4.7A)
None
None
 1.09A 3w9tF-3ke6A:
undetectable		 3w9tF-3ke6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 5 ASP A 211
VAL A 213
GLY A 214
ASP A 387
 MN  A   2 ( 2.5A)
MN  A 541 ( 4.7A)
None
MN  A   2 (-2.6A)
 0.86A 3w9tG-3ke6A:
undetectable		 3w9tG-3ke6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 5 ASP A 211
VAL A 213
GLY A 214
ASP A 388
 MN  A   2 ( 2.5A)
MN  A 541 ( 4.7A)
None
None
 1.07A 3w9tG-3ke6A:
undetectable		 3w9tG-3ke6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 7 ILE A 438
LEU A 521
PHE A 445
GLY A 497
 None
 1.03A 4hajA-3ke6A:
undetectable		 4hajA-3ke6A:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 6 ASP A 211
ASP A 194
TYR A 385
ASP A 328
 MN  A   2 ( 2.5A)
None
None
MN  A   2 (-2.4A)
 1.04A 4mdaA-3ke6A:
undetectable		 4mdaA-3ke6A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 6 ASP A 211
ASP A 194
TYR A 385
ASP A 328
 MN  A   2 ( 2.5A)
None
None
MN  A   2 (-2.4A)
 1.02A 4mdbA-3ke6A:
undetectable		 4mdbA-3ke6A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		3 / 3 GLY A 302
PRO A 303
ALA A 260
 None
 0.48A 4qn9B-3ke6A:
undetectable		 4qn9B-3ke6A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 6 VAL A 474
HIS A 523
LEU A 525
LEU A 425
 None
 1.09A 5hrqB-3ke6A:
undetectable
5hrqI-3ke6A:
undetectable
5hrqJ-3ke6A:
undetectable		 5hrqB-3ke6A:
5.84
5hrqI-3ke6A:
6.15
5hrqJ-3ke6A:
5.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		5 / 12 ILE A 234
LEU A 201
VAL A 173
LEU A 392
GLY A 175
 None
 1.16A 5ienA-3ke6A:
undetectable		 5ienA-3ke6A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 6 VAL A 450
VAL A 417
SER A 443
ILE A 438
 None
 0.99A 5jw1B-3ke6A:
undetectable		 5jw1B-3ke6A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 304
ASP A 211
GLY A 210
ALA A 229
VAL A 222
 None
MN  A   2 ( 2.5A)
None
None
None
 1.29A 5kbwB-3ke6A:
undetectable		 5kbwB-3ke6A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 7 GLY A 175
ALA A 176
ASP A 177
GLY A 320
 None
 0.67A 5kqyB-3ke6A:
undetectable		 5kqyB-3ke6A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 8 GLY A 175
ALA A 176
ASP A 177
GLY A 320
 None
 0.58A 5kr1B-3ke6A:
undetectable		 5kr1B-3ke6A:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 5 ALA A 508
VAL A 505
PHE A 445
ILE A 438
 None
 1.01A 5of1A-3ke6A:
undetectable		 5of1A-3ke6A:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 5 ALA A 508
VAL A 505
PHE A 445
ILE A 438
 None
 1.00A 5of1B-3ke6A:
undetectable		 5of1B-3ke6A:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 9 PHE A 325
VAL A 209
LEU A 376
ASP A 388
 None
 0.97A 6c2mD-3ke6A:
undetectable		 6c2mD-3ke6A:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		4 / 8 ILE A 428
VAL A 474
PRO A 174
ALA A 476
 None
 0.80A 6cduD-3ke6A:
2.5
6cduE-3ke6A:
2.5		 6cduD-3ke6A:
21.21
6cduE-3ke6A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3ke6 PROTEIN
RV1364C/MT1410
(Mycobacterium
tuberculosis) 		5 / 11 VAL A 170
SER A 169
VAL A 206
LEU A 205
TYR A  -6
 None
 1.27A 6dryA-3ke6A:
undetectable		 6dryA-3ke6A:
21.80