SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3keh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 12 ALA A  89
ALA A  90
LEU A 383
ALA A 384
HIS A 162
 None
 1.03A 1fbyA-3kehA:
undetectable		 1fbyA-3kehA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 12 ALA A  89
ALA A  90
LEU A 383
ALA A 384
HIS A 162
 None
 1.02A 1fbyB-3kehA:
undetectable		 1fbyB-3kehA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 10 LEU A 249
ASN A 188
GLY A 189
TRP A 209
LEU A 197
 None
 1.12A 1fkoA-3kehA:
0.7		 1fkoA-3kehA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 12 ALA A  89
ALA A  90
LEU A 383
ALA A 384
HIS A 162
 None
 1.03A 1fm6U-3kehA:
undetectable		 1fm6U-3kehA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		3 / 3 TRP A 312
TYR A 313
LEU A 286
 None
 1.10A 1kxhA-3kehA:
1.6		 1kxhA-3kehA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		3 / 3 ARG A 285
ASP A 445
ASN A 462
 None
 0.96A 1nbhA-3kehA:
undetectable		 1nbhA-3kehA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_D_DEXD4999_1
(GLUCOCORTICOID
RECEPTOR)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 12 GLY A 115
GLN A 169
PHE A  26
MET A  49
ILE A 402
 None
SO4  A1502 (-3.8A)
GOL  A1509 (-3.8A)
None
None
 1.35A 1p93D-3kehA:
undetectable		 1p93D-3kehA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_2
(PROTEASE RETROPEPSIN)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 12 ALA A 232
GLY A 307
ILE A 308
ALA A 301
ILE A 260
 None
 0.88A 1rl8B-3kehA:
undetectable		 1rl8B-3kehA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 12 ALA A  89
ALA A  90
LEU A 160
ILE A 161
ALA A 384
 None
 0.81A 2aclG-3kehA:
undetectable		 2aclG-3kehA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 12 ALA A 232
GLY A 307
ILE A 308
ALA A 301
ILE A 260
 None
 0.84A 2b60A-3kehA:
undetectable		 2b60A-3kehA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		4 / 7 TRP A 378
TYR A 108
TYR A 363
ILE A 367
 None
 1.11A 2ph9A-3kehA:
undetectable
2ph9B-3kehA:
undetectable		 2ph9A-3kehA:
17.03
2ph9B-3kehA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 12 ALA A 232
GLY A 307
ILE A 308
ALA A 301
ILE A 260
 None
 0.82A 2rkfA-3kehA:
undetectable		 2rkfA-3kehA:
12.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		7 / 12 ASP A 127
TRP A 179
ASN A 234
GLU A 235
HIS A 311
GLU A 340
TRP A 381
 None
 0.32A 2v3dA-3kehA:
65.1		 2v3dA-3kehA:
99.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		6 / 12 ASP A 127
TRP A 179
ASN A 234
GLU A 340
TRP A 381
ASN A 392
 None
 1.32A 2v3dA-3kehA:
65.1		 2v3dA-3kehA:
99.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		7 / 12 ASP A 127
TRP A 179
ASN A 234
HIS A 311
TYR A 313
GLU A 340
TRP A 381
 None
 0.73A 2v3dA-3kehA:
65.1		 2v3dA-3kehA:
99.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		7 / 11 ASP A 127
TRP A 179
ASN A 234
GLU A 235
TYR A 313
GLU A 340
TRP A 381
 None
 0.77A 2v3dB-3kehA:
62.6		 2v3dB-3kehA:
99.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		6 / 11 ASP A 127
TRP A 179
ASN A 234
GLU A 340
TRP A 381
ASN A 392
 None
 1.28A 2v3dB-3kehA:
62.6		 2v3dB-3kehA:
99.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		3 / 3 SER A 110
ARG A 170
GLN A 169
 None
SO4  A1502 (-4.1A)
SO4  A1502 (-3.8A)
 1.02A 2xnrA-3kehA:
undetectable		 2xnrA-3kehA:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 12 THR A 154
ASP A 153
VAL A 121
PHE A 227
TYR A 135
 None
 1.48A 2y04B-3kehA:
undetectable		 2y04B-3kehA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 10 ALA A 232
GLY A 307
ILE A 308
ALA A 301
ILE A 260
 None
 0.95A 3ekpC-3kehA:
undetectable		 3ekpC-3kehA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_2
(PROTEASE)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 9 ALA A 232
GLY A 307
ILE A 308
ALA A 301
ILE A 260
 None
 0.96A 3ektB-3kehA:
undetectable		 3ektB-3kehA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_1
(PROTEASE)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 10 ALA A 232
GLY A 307
ILE A 308
ALA A 301
ILE A 260
 None
 1.02A 3ekwA-3kehA:
undetectable		 3ekwA-3kehA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 12 VAL A 121
ALA A  89
ALA A  90
LEU A 383
ALA A 384
 None
 0.89A 3fc6C-3kehA:
undetectable		 3fc6C-3kehA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		4 / 6 ALA A 232
ILE A 260
LEU A 278
ALA A 309
 None
 0.65A 3r9sA-3kehA:
undetectable		 3r9sA-3kehA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		4 / 6 ALA A 232
ILE A 260
LEU A 278
ALA A 309
 None
 0.67A 3r9sC-3kehA:
undetectable		 3r9sC-3kehA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 12 LEU A 354
PHE A   9
GLY A 389
GLU A 388
ASP A 405
 None
 1.35A 3tbgC-3kehA:
undetectable		 3tbgC-3kehA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		3 / 3 VAL A 376
TRP A 312
TRP A 378
 None
 1.32A 3zq8A-3kehA:
undetectable
3zq8B-3kehA:
undetectable		 3zq8A-3kehA:
9.02
3zq8B-3kehA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 11 THR A 231
ALA A 232
LEU A 264
PHE A 259
SER A 177
 None
 1.49A 4claA-3kehA:
undetectable		 4claA-3kehA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		4 / 8 VAL A  17
PHE A   9
LEU A 354
LYS A   7
 None
 1.09A 4f8hB-3kehA:
undetectable
4f8hC-3kehA:
undetectable		 4f8hB-3kehA:
21.43
4f8hC-3kehA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_C_RKEC401_1
(PROTON-GATED ION
CHANNEL)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		4 / 8 VAL A  17
PHE A   9
LEU A 354
LYS A   7
 None
 1.09A 4f8hC-3kehA:
undetectable
4f8hD-3kehA:
undetectable		 4f8hC-3kehA:
21.43
4f8hD-3kehA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		4 / 8 VAL A  17
PHE A   9
LEU A 354
LYS A   7
 None
 1.09A 4f8hA-3kehA:
undetectable
4f8hE-3kehA:
undetectable		 4f8hA-3kehA:
21.43
4f8hE-3kehA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		4 / 8 SER A  13
GLU A  41
TYR A  40
GLY A 421
 None
 0.99A 4fgzA-3kehA:
undetectable
4fgzB-3kehA:
undetectable		 4fgzA-3kehA:
18.88
4fgzB-3kehA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		3 / 3 TYR A  11
ARG A 359
SER A 356
 SO4  A1504 (-4.7A)
None
SO4  A1504 (-2.6A)
 1.01A 4lf7I-3kehA:
undetectable
4lf7J-3kehA:
undetectable		 4lf7I-3kehA:
15.29
4lf7J-3kehA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		3 / 3 TYR A  11
ARG A 359
SER A 356
 SO4  A1504 (-4.7A)
None
SO4  A1504 (-2.6A)
 1.01A 4lf8I-3kehA:
undetectable
4lf8J-3kehA:
undetectable		 4lf8I-3kehA:
15.29
4lf8J-3kehA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0U_A_ADNA501_1
(AURORA KINASE A)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 6 VAL A 458
ALA A 446
LEU A  65
THR A 482
LEU A 470
 None
 1.14A 4o0uA-3kehA:
undetectable		 4o0uA-3kehA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 11 HIS A 311
SER A 339
THR A 231
GLY A 307
ALA A 309
 None
 1.44A 4qvqH-3kehA:
undetectable
4qvqN-3kehA:
undetectable		 4qvqH-3kehA:
19.72
4qvqN-3kehA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 11 HIS A 311
SER A 339
THR A 231
GLY A 307
ALA A 309
 None
 1.44A 4qw3H-3kehA:
undetectable
4qw3N-3kehA:
undetectable		 4qw3H-3kehA:
19.72
4qw3N-3kehA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		4 / 7 THR A 132
TYR A 133
THR A 134
SER A 125
 None
 1.29A 5b6iA-3kehA:
undetectable		 5b6iA-3kehA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_B_ADNB302_1
(FLUORINASE)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		4 / 6 THR A 132
TYR A 133
THR A 134
SER A 125
 None
 1.29A 5b6iB-3kehA:
undetectable		 5b6iB-3kehA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		4 / 5 LEU A 160
PHE A 109
ILE A 161
ILE A 119
 None
 1.08A 5dzk4-3kehA:
undetectable
5dzkg-3kehA:
undetectable
5dzkm-3kehA:
undetectable
5dzkn-3kehA:
undetectable		 5dzk4-3kehA:
3.03
5dzkg-3kehA:
18.43
5dzkm-3kehA:
17.23
5dzkn-3kehA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		4 / 8 PHE A  31
SER A 455
HIS A 451
LEU A 493
 None
 1.15A 5dzkd-3kehA:
undetectable
5dzkr-3kehA:
undetectable		 5dzkd-3kehA:
18.43
5dzkr-3kehA:
3.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 11 HIS A 311
SER A 339
THR A 231
GLY A 307
ALA A 309
 None
 1.44A 5l66V-3kehA:
undetectable
5l66b-3kehA:
undetectable		 5l66V-3kehA:
19.72
5l66b-3kehA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 11 HIS A 311
SER A 339
THR A 231
GLY A 307
ALA A 309
 None
 1.44A 5l66H-3kehA:
undetectable
5l66N-3kehA:
undetectable		 5l66H-3kehA:
19.72
5l66N-3kehA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		4 / 7 TYR A 412
ILE A 403
ILE A 402
ILE A  93
 None
 0.91A 5murB-3kehA:
undetectable		 5murB-3kehA:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 12 LEU A 372
ILE A 368
ASP A 445
ARG A 463
LEU A 317
 None
 1.21A 5nn8A-3kehA:
3.7		 5nn8A-3kehA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAH_C_RFPC3001_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 12 ARG A  39
LEU A 470
LEU A  66
PRO A 475
ARG A 496
 None
 1.42A 5uahC-3kehA:
0.0		 5uahC-3kehA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		4 / 7 PHE A 426
VAL A 457
ILE A 367
THR A 491
 None
 0.98A 5vkqA-3kehA:
undetectable
5vkqD-3kehA:
undetectable		 5vkqA-3kehA:
14.60
5vkqD-3kehA:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_B_C2FB702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 12 GLY A  82
VAL A 459
LEU A 449
PHE A 337
ILE A 367
 None
 1.07A 5vooB-3kehA:
7.6		 5vooB-3kehA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_1
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		4 / 4 SER A 464
ASP A 445
HIS A 365
ASP A 443
 None
 1.15A 5x7fA-3kehA:
0.8		 5x7fA-3kehA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		4 / 8 GLU A 340
HIS A 223
PHE A 216
LEU A 149
 None
 1.10A 5y2tB-3kehA:
undetectable		 5y2tB-3kehA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 9 VAL A 460
LEU A 444
GLY A  64
LEU A  65
THR A 482
 None
 1.12A 6czmA-3kehA:
undetectable
6czmB-3kehA:
undetectable		 6czmA-3kehA:
22.51
6czmB-3kehA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 9 VAL A 460
LEU A 444
GLY A  64
LEU A  65
THR A 482
 None
 1.11A 6czmD-3kehA:
undetectable
6czmE-3kehA:
undetectable		 6czmD-3kehA:
22.51
6czmE-3kehA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		5 / 10 VAL A 460
LEU A 444
GLY A  64
LEU A  65
THR A 482
 None
 1.11A 6czmE-3kehA:
undetectable
6czmF-3kehA:
undetectable		 6czmE-3kehA:
22.51
6czmF-3kehA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 3keh GLUCOCEREBROSIDASE
(Homo
sapiens) 		4 / 5 LEU A  66
THR A 471
THR A  63
GLY A  62
 None
 1.13A 6gtqA-3kehA:
undetectable		 6gtqA-3kehA:
16.80