SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ker'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA187_1
(DIHYDROFOLATE
REDUCTASE)		 3ker D-DOPACHROME
DECARBOXYLASE
(Mus
musculus) 		5 / 12 ILE A  97
PHE A  83
PHE A  80
LEU A  30
VAL A  61
 None
 0.95A 3s3vA-3kerA:
undetectable		 3s3vA-3kerA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3ker D-DOPACHROME
DECARBOXYLASE
(Mus
musculus) 		5 / 11 GLU A  19
LEU A  22
LEU A   5
LEU A  88
LEU A  84
 None
 1.00A 4wg0C-3kerA:
undetectable
4wg0D-3kerA:
undetectable
4wg0E-3kerA:
undetectable		 4wg0C-3kerA:
10.64
4wg0D-3kerA:
10.64
4wg0E-3kerA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3ker D-DOPACHROME
DECARBOXYLASE
(Mus
musculus) 		5 / 11 GLU A  19
LEU A  22
LEU A   5
LEU A  88
LEU A  84
 None
 1.00A 4wg0E-3kerA:
undetectable
4wg0F-3kerA:
undetectable
4wg0G-3kerA:
undetectable		 4wg0E-3kerA:
10.64
4wg0F-3kerA:
10.64
4wg0G-3kerA:
10.64