SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kes'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 3kes NUCLEOPORIN NUP145
(Saccharomyces
cerevisiae) 		5 / 9 ILE A 494
PHE A 520
GLY A 492
ILE A 548
ALA A 546
 None
None
EDO  A   4 ( 4.8A)
None
None
 1.30A 1mrgA-3kesA:
undetectable		 1mrgA-3kesA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3kes NUCLEOPORIN NUP145
(Saccharomyces
cerevisiae) 		4 / 5 PRO A 555
PRO A 593
GLY A 596
TYR A 554
 None
EDO  A   7 ( 4.4A)
None
None
 1.09A 2jkjD-3kesA:
undetectable		 2jkjD-3kesA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3kes NUCLEOPORIN NUP145
(Saccharomyces
cerevisiae) 		4 / 5 PRO A 555
PRO A 593
GLY A 596
TYR A 554
 None
EDO  A   7 ( 4.4A)
None
None
 1.08A 2jkjF-3kesA:
undetectable		 2jkjF-3kesA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 3kes NUCLEOPORIN NUP145
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 573
PRO A 593
THR A 597
TRP A 598
 None
EDO  A   7 ( 4.4A)
None
None
 1.47A 2q6kA-3kesA:
undetectable		 2q6kA-3kesA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 3kes NUCLEOPORIN NUP145
(Saccharomyces
cerevisiae) 		4 / 6 PHE A 573
PRO A 593
THR A 597
TRP A 598
 None
EDO  A   7 ( 4.4A)
None
None
 1.45A 2q6oB-3kesA:
undetectable		 2q6oB-3kesA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 3kes NUCLEOPORIN NUP145
(Saccharomyces
cerevisiae) 		5 / 11 GLY A 541
ALA A 546
VAL A 500
PHE A 505
ILE A 517
 None
 1.35A 4j4vA-3kesA:
undetectable		 4j4vA-3kesA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_D_SVRD301_1
(NUCLEOCAPSID PROTEIN)		 3kes NUCLEOPORIN NUP145
(Saccharomyces
cerevisiae) 		5 / 11 GLY A 541
ALA A 546
VAL A 500
PHE A 505
ILE A 517
 None
 1.48A 4j4vD-3kesA:
undetectable
4j4vE-3kesA:
undetectable		 4j4vD-3kesA:
20.47
4j4vE-3kesA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 3kes NUCLEOPORIN NUP145
(Saccharomyces
cerevisiae) 		5 / 9 ILE A 494
PHE A 520
GLY A 492
ILE A 548
ALA A 546
 None
None
EDO  A   4 ( 4.8A)
None
None
 1.33A 4yp2B-3kesA:
undetectable		 4yp2B-3kesA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 3kes NUCLEOPORIN NUP145
(Saccharomyces
cerevisiae) 		5 / 9 ILE A 494
PHE A 520
GLY A 492
ILE A 548
ALA A 546
 None
None
EDO  A   4 ( 4.8A)
None
None
 1.31A 5cf9B-3kesA:
undetectable		 5cf9B-3kesA:
22.27