SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kf8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3kf8 PROTEIN TEN1
(Candida
tropicalis) 		4 / 8 TYR B  86
PHE B  85
GLU B  89
GLY B  88
 None
 1.09A 1ykiA-3kf8B:
undetectable
1ykiB-3kf8B:
undetectable		 1ykiA-3kf8B:
21.30
1ykiB-3kf8B:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3kf8 PROTEIN STN1
(Candida
tropicalis) 		5 / 11 ALA A  40
GLN A  39
LEU A  36
PHE A  37
ILE A  63
 None
 1.09A 2aclE-3kf8A:
undetectable		 2aclE-3kf8A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_2
(DIHYDROFOLATE
REDUCTASE)		 3kf8 PROTEIN TEN1
(Candida
tropicalis) 		4 / 4 ILE B  42
ARG B  25
ILE B  60
THR B  78
 None
 1.04A 3ia4C-3kf8B:
undetectable		 3ia4C-3kf8B:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPC_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3kf8 PROTEIN TEN1
(Candida
tropicalis) 		5 / 11 ILE B  58
ILE B  82
ASN B  92
ILE B  91
PRO B   8
 None
 1.12A 3kpcA-3kf8B:
undetectable		 3kpcA-3kf8B:
27.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3kf8 PROTEIN TEN1
(Candida
tropicalis) 		5 / 12 ILE B  58
ILE B  82
ASN B  92
ILE B  91
PRO B   8
 None
 1.11A 3kpdB-3kf8B:
undetectable		 3kpdB-3kf8B:
27.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3kf8 PROTEIN STN1
(Candida
tropicalis) 		4 / 8 SER A  52
SER A 121
ASN A  55
GLY A  89
 None
 0.93A 4af0A-3kf8A:
undetectable		 4af0A-3kf8A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYS_A_ACTA402_0
(MCCC FAMILY PROTEIN)		 3kf8 PROTEIN STN1
PROTEIN TEN1
(Candida
tropicalis;
Candida
tropicalis) 		4 / 6 SER A 114
ASP B  83
ARG B  27
GLU A 189
 None
 1.24A 4eysA-3kf8A:
undetectable		 4eysA-3kf8A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 3kf8 PROTEIN TEN1
(Candida
tropicalis) 		4 / 7 TYR B  86
ILE B  60
ILE B  82
ALA B  84
 None
 0.86A 4lv9A-3kf8B:
undetectable		 4lv9A-3kf8B:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3kf8 PROTEIN STN1
(Candida
tropicalis) 		5 / 12 ILE A 154
THR A  46
ILE A  47
LEU A  49
ILE A  85
 None
 1.07A 4pthA-3kf8A:
undetectable		 4pthA-3kf8A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 3kf8 PROTEIN TEN1
(Candida
tropicalis) 		4 / 7 ILE B  60
LEU B  65
ALA B  84
ILE B  91
 None
 0.86A 4y03A-3kf8B:
undetectable		 4y03A-3kf8B:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 3kf8 PROTEIN STN1
(Candida
tropicalis) 		4 / 6 ILE A  85
VAL A  77
VAL A  82
SER A  57
 None
 0.99A 5jwaH-3kf8A:
undetectable		 5jwaH-3kf8A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 3kf8 PROTEIN TEN1
(Candida
tropicalis) 		4 / 8 ILE B  82
ASN B  59
PRO B  48
PRO B   8
 None
 0.86A 5x23A-3kf8B:
undetectable		 5x23A-3kf8B:
11.90