SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kfo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 3kfo NUCLEOPORIN NUP133
(Saccharomyces
cerevisiae) 		3 / 3 GLU A1012
HIS A1060
ASP A1067
 None
 0.69A 1i9gA-3kfoA:
undetectable		 1i9gA-3kfoA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA733_1
(ALPHA AMYLASE)		 3kfo NUCLEOPORIN NUP133
(Saccharomyces
cerevisiae) 		4 / 6 SER A1051
ASN A1049
LEU A1058
ASP A1055
 None
 1.10A 1mxdA-3kfoA:
undetectable		 1mxdA-3kfoA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA443_1
(ALPHA AMYLASE)		 3kfo NUCLEOPORIN NUP133
(Saccharomyces
cerevisiae) 		4 / 8 SER A1051
ASN A1049
LEU A1058
ASP A1055
 None
 1.11A 1mxgA-3kfoA:
undetectable		 1mxgA-3kfoA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q0Y_H_MOIH401_1
(FAB 9B1, HEAVY CHAIN
FAB 9B1, LIGHT CHAIN)		 3kfo NUCLEOPORIN NUP133
(Saccharomyces
cerevisiae) 		4 / 7 GLU A1116
GLU A1112
ILE A 980
LEU A1090
 None
 1.27A 1q0yH-3kfoA:
undetectable
1q0yL-3kfoA:
undetectable		 1q0yH-3kfoA:
19.80
1q0yL-3kfoA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3kfo NUCLEOPORIN NUP133
(Saccharomyces
cerevisiae) 		4 / 7 TYR A1094
LEU A1037
VAL A 983
ILE A1109
 None
 0.84A 1t87B-3kfoA:
undetectable		 1t87B-3kfoA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 3kfo NUCLEOPORIN NUP133
(Saccharomyces
cerevisiae) 		4 / 6 LEU A1037
ASN A1038
LEU A1015
ILE A1061
 None
GOL  A   1 ( 4.3A)
None
None
 0.96A 1z95A-3kfoA:
undetectable		 1z95A-3kfoA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 3kfo NUCLEOPORIN NUP133
(Saccharomyces
cerevisiae) 		3 / 3 VAL A1081
ASP A1082
GLU A1130
 None
 0.59A 2qeuA-3kfoA:
undetectable		 2qeuA-3kfoA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_C_ACTC141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 3kfo NUCLEOPORIN NUP133
(Saccharomyces
cerevisiae) 		3 / 3 VAL A1081
ASP A1082
GLU A1130
 None
 0.57A 2qeuC-3kfoA:
undetectable		 2qeuC-3kfoA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 3kfo NUCLEOPORIN NUP133
(Saccharomyces
cerevisiae) 		4 / 6 ASP A1001
TYR A1006
PHE A 984
LEU A 964
 None
 1.02A 2w98A-3kfoA:
undetectable
2w98B-3kfoA:
undetectable		 2w98A-3kfoA:
21.22
2w98B-3kfoA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_A_ACTA501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 3kfo NUCLEOPORIN NUP133
(Saccharomyces
cerevisiae) 		4 / 7 ARG A1020
VAL A1065
ARG A1064
ILE A1061
 None
 1.06A 2yfbA-3kfoA:
undetectable		 2yfbA-3kfoA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 3kfo NUCLEOPORIN NUP133
(Saccharomyces
cerevisiae) 		3 / 3 LEU A1021
GLU A 957
ILE A 960
 None
 0.60A 3czhA-3kfoA:
undetectable		 3czhA-3kfoA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 3kfo NUCLEOPORIN NUP133
(Saccharomyces
cerevisiae) 		4 / 6 ARG A1044
LEU A1002
PRO A1018
SER A1007
 None
 1.34A 3vlnA-3kfoA:
undetectable		 3vlnA-3kfoA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZS3_A_ACTA1224_0
(THAUMATIN-LIKE
PROTEIN)		 3kfo NUCLEOPORIN NUP133
(Saccharomyces
cerevisiae) 		4 / 5 SER A 993
GLU A 990
THR A 995
ASP A1001
 None
 1.47A 3zs3A-3kfoA:
undetectable		 3zs3A-3kfoA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 3kfo NUCLEOPORIN NUP133
(Saccharomyces
cerevisiae) 		4 / 8 TYR A1094
LEU A1037
LEU A1040
VAL A 983
 None
 0.80A 4c9nA-3kfoA:
undetectable		 4c9nA-3kfoA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3kfo NUCLEOPORIN NUP133
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 952
VAL A 997
ASN A1027
 None
 0.67A 4lmnA-3kfoA:
undetectable		 4lmnA-3kfoA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3kfo NUCLEOPORIN NUP133
(Saccharomyces
cerevisiae) 		3 / 3 GLU A1012
HIS A1060
ASP A1067
 None
 0.55A 5c0oG-3kfoA:
undetectable		 5c0oG-3kfoA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3kfo NUCLEOPORIN NUP133
(Saccharomyces
cerevisiae) 		4 / 8 LEU A1058
PRO A1079
ILE A1045
LEU A1057
 None
 0.88A 5g48A-3kfoA:
undetectable		 5g48A-3kfoA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 3kfo NUCLEOPORIN NUP133
(Saccharomyces
cerevisiae) 		5 / 12 PHE A1016
ILE A1061
VAL A1041
ILE A1045
PRO A1079
 None
 1.48A 5mlmA-3kfoA:
undetectable		 5mlmA-3kfoA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_F_RBFF201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 3kfo NUCLEOPORIN NUP133
(Saccharomyces
cerevisiae) 		4 / 7 LEU A1090
ARG A1043
GLU A1004
SER A1007
 None
 1.20A 5umwA-3kfoA:
undetectable
5umwF-3kfoA:
undetectable		 5umwA-3kfoA:
17.05
5umwF-3kfoA:
17.05