SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kfw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDT_A_VIAA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3kfw UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 TYR X  61
ALA X 233
ALA X  32
LEU X  41
GLN X  29
 None
 1.15A 1udtA-3kfwX:
undetectable		 1udtA-3kfwX:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 3kfw UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 ARG X 231
ASP X  75
GLN X  74
 None
 0.87A 4azsA-3kfwX:
undetectable		 4azsA-3kfwX:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3kfw UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 8 SER X  25
ARG X 230
ILE X  28
GLU X  26
 None
 1.17A 4cx7A-3kfwX:
undetectable
4cx7B-3kfwX:
undetectable		 4cx7A-3kfwX:
19.63
4cx7B-3kfwX:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3kfw UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 8 SER X  25
ARG X 230
ILE X  28
GLU X  26
 None
 1.25A 4cx7C-3kfwX:
undetectable
4cx7D-3kfwX:
undetectable		 4cx7C-3kfwX:
19.63
4cx7D-3kfwX:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F5Z_A_BEZA302_0
(HALOALKANE
DEHALOGENASE)		 3kfw UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 8 ASN X 129
ASP X 128
TRP X  85
HIS X  90
 None
 1.23A 4f5zA-3kfwX:
undetectable		 4f5zA-3kfwX:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA207_0
(OXIDOREDUCTASE)		 3kfw UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 4 GLU X 118
GLY X 117
HIS X 112
ARG X 108
 None
 1.12A 4r82A-3kfwX:
undetectable
4r82B-3kfwX:
undetectable		 4r82A-3kfwX:
25.49
4r82B-3kfwX:
25.49