SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kg4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_A_CHCA202_1
(BILE ACID RECEPTOR)		 3kg4 UNCHARACTERIZED
PROTEIN
([Mannheimia]
succiniciproduce
ns) 		5 / 12 PHE A  16
SER A  27
PHE A  64
ILE A  62
TYR A 114
 None
 1.38A 1osvA-3kg4A:
undetectable		 1osvA-3kg4A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_B_CHCB201_1
(BILE ACID RECEPTOR)		 3kg4 UNCHARACTERIZED
PROTEIN
([Mannheimia]
succiniciproduce
ns) 		5 / 12 LEU A 186
PHE A  16
SER A  27
PHE A  64
TYR A 114
 None
 1.38A 1osvB-3kg4A:
undetectable		 1osvB-3kg4A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OSV_B_CHCB201_1
(BILE ACID RECEPTOR)		 3kg4 UNCHARACTERIZED
PROTEIN
([Mannheimia]
succiniciproduce
ns) 		5 / 12 PHE A  16
SER A  27
PHE A  64
ILE A  62
TYR A 114
 None
 1.30A 1osvB-3kg4A:
undetectable		 1osvB-3kg4A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OT7_A_CHCA1001_1
(BILE ACID RECEPTOR)		 3kg4 UNCHARACTERIZED
PROTEIN
([Mannheimia]
succiniciproduce
ns) 		5 / 12 PHE A  16
SER A  27
PHE A  64
ILE A  62
TYR A 114
 None
 1.35A 1ot7A-3kg4A:
undetectable		 1ot7A-3kg4A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3kg4 UNCHARACTERIZED
PROTEIN
([Mannheimia]
succiniciproduce
ns) 		5 / 10 LEU A   7
ALA A 118
ILE A   5
MET A 138
PHE A 139
 None
 0.98A 1xp0A-3kg4A:
undetectable		 1xp0A-3kg4A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_A_VDNA1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3kg4 UNCHARACTERIZED
PROTEIN
([Mannheimia]
succiniciproduce
ns) 		5 / 12 LEU A   7
ALA A 118
ILE A   5
MET A 138
PHE A 139
 None
 1.03A 3b2rA-3kg4A:
undetectable		 3b2rA-3kg4A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_B_VDNB1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3kg4 UNCHARACTERIZED
PROTEIN
([Mannheimia]
succiniciproduce
ns) 		5 / 11 LEU A   7
ALA A 118
ILE A   5
MET A 138
PHE A 139
 None
 1.06A 3b2rB-3kg4A:
undetectable		 3b2rB-3kg4A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 3kg4 UNCHARACTERIZED
PROTEIN
([Mannheimia]
succiniciproduce
ns) 		3 / 3 PHE A 159
VAL A 108
GLU A  65
 None
 0.77A 4fvqA-3kg4A:
undetectable		 4fvqA-3kg4A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 3kg4 UNCHARACTERIZED
PROTEIN
([Mannheimia]
succiniciproduce
ns) 		4 / 9 TYR A  28
LYS A  22
PHE A 203
ILE A 193
 None
 1.28A 4jvlA-3kg4A:
undetectable		 4jvlA-3kg4A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 3kg4 UNCHARACTERIZED
PROTEIN
([Mannheimia]
succiniciproduce
ns) 		3 / 3 ALA A 118
TRP A  51
VAL A  52
 None
 0.40A 4w9nC-3kg4A:
undetectable		 4w9nC-3kg4A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_0
(METHYLTRANSFERASE)		 3kg4 UNCHARACTERIZED
PROTEIN
([Mannheimia]
succiniciproduce
ns) 		5 / 12 ALA A 113
VAL A 112
GLU A 117
PHE A  16
ALA A  36
 None
 1.15A 5n5dA-3kg4A:
undetectable		 5n5dA-3kg4A:
21.46