SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kg5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 3kg5 B-CELL ANTIGEN
RECEPTOR
COMPLEX-ASSOCIATED
PROTEIN BETA CHAIN
(Homo
sapiens) 		4 / 6 MET A  96
VAL A 142
LEU A 140
MET A  63
 None
 1.08A 1x8vA-3kg5A:
undetectable		 1x8vA-3kg5A:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O7O_A_DXTA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3kg5 B-CELL ANTIGEN
RECEPTOR
COMPLEX-ASSOCIATED
PROTEIN BETA CHAIN
(Homo
sapiens) 		5 / 12 SER A  69
ASN A  68
VAL A  74
GLN A 124
ILE A  46
 None
 1.41A 2o7oA-3kg5A:
undetectable		 2o7oA-3kg5A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XPV_A_MIYA1209_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3kg5 B-CELL ANTIGEN
RECEPTOR
COMPLEX-ASSOCIATED
PROTEIN BETA CHAIN
(Homo
sapiens) 		5 / 12 SER A  69
ASN A  68
VAL A  74
GLN A 124
ILE A  46
 None
 1.33A 2xpvA-3kg5A:
undetectable		 2xpvA-3kg5A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XPW_A_OTCA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3kg5 B-CELL ANTIGEN
RECEPTOR
COMPLEX-ASSOCIATED
PROTEIN BETA CHAIN
(Homo
sapiens) 		5 / 12 SER A  69
ASN A  68
VAL A  74
GLN A 124
ILE A  46
 None
 1.41A 2xpwA-3kg5A:
undetectable		 2xpwA-3kg5A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3kg5 B-CELL ANTIGEN
RECEPTOR
COMPLEX-ASSOCIATED
PROTEIN BETA CHAIN
(Homo
sapiens) 		3 / 3 SER A  69
GLY A  72
GLN A 124
 None
 0.64A 3v4tH-3kg5A:
undetectable		 3v4tH-3kg5A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3kg5 B-CELL ANTIGEN
RECEPTOR
COMPLEX-ASSOCIATED
PROTEIN BETA CHAIN
(Homo
sapiens) 		4 / 5 ARG A  95
ILE A 112
GLY A 118
ILE A 109
 None
 0.81A 5dzki-3kg5A:
undetectable
5dzkj-3kg5A:
undetectable
5dzkx-3kg5A:
undetectable		 5dzki-3kg5A:
18.23
5dzkj-3kg5A:
18.23
5dzkx-3kg5A:
3.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3kg5 B-CELL ANTIGEN
RECEPTOR
COMPLEX-ASSOCIATED
PROTEIN BETA CHAIN
(Homo
sapiens) 		3 / 3 THR A 108
MET A  63
HIS A  64
 None
 0.94A 5uunA-3kg5A:
undetectable		 5uunA-3kg5A:
17.06