SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kg6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 3kg6 CURF
(Lyngbya
majuscula) 		5 / 12 ILE A1788
LEU A1759
ALA A1806
PHE A1786
LEU A1734
 None
 1.02A 1og5B-3kg6A:
undetectable		 1og5B-3kg6A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 3kg6 CURF
(Lyngbya
majuscula) 		4 / 7 PHE A1728
ILE A1764
THR A1731
ILE A1769
 None
 0.98A 2v0mB-3kg6A:
undetectable		 2v0mB-3kg6A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 3kg6 CURF
(Lyngbya
majuscula) 		5 / 12 HIS A1840
ILE A1858
LEU A1947
VAL A1956
TYR A1844
 None
 1.22A 3sp9B-3kg6A:
undetectable		 3sp9B-3kg6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TF1_A_ACTA191_0
(METHYL-ACCEPTING
CHEMOTAXIS PROTEIN)		 3kg6 CURF
(Lyngbya
majuscula) 		4 / 5 THR A1926
ILE A1927
PHE A1874
LEU A1882
 None
 1.34A 3tf1A-3kg6A:
undetectable		 3tf1A-3kg6A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_1
(METHYLTRANSFERASE
WBDD)		 3kg6 CURF
(Lyngbya
majuscula) 		3 / 3 GLN A1819
ASP A1949
GLN A1951
 None
 0.84A 4aztA-3kg6A:
undetectable		 4aztA-3kg6A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 3kg6 CURF
(Lyngbya
majuscula) 		3 / 3 PHE A1728
TYR A1885
TYR A1716
 None
 1.05A 4ffwA-3kg6A:
undetectable		 4ffwA-3kg6A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 3kg6 CURF
(Lyngbya
majuscula) 		3 / 3 GLU A1959
TYR A1811
GLU A1813
 None
 0.77A 4ryaA-3kg6A:
undetectable		 4ryaA-3kg6A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3kg6 CURF
(Lyngbya
majuscula) 		5 / 12 ILE A1927
THR A1926
GLN A1925
VAL A1751
GLU A1735
 None
 1.25A 6bzoC-3kg6A:
undetectable		 6bzoC-3kg6A:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 3kg6 CURF
(Lyngbya
majuscula) 		4 / 5 GLY A1715
LEU A1717
TYR A1885
GLN A1881
 None
 1.04A 6ji6A-3kg6A:
undetectable		 6ji6A-3kg6A:
18.86