SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kg9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 3kg9 CURK
(Lyngbya
majuscula) 		4 / 8 LEU A1167
ALA A1158
LEU A1163
LEU A1020
 None
 0.94A 1dvtA-3kg9A:
undetectable
1dvtB-3kg9A:
undetectable		 1dvtA-3kg9A:
17.11
1dvtB-3kg9A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB504_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3kg9 CURK
(Lyngbya
majuscula) 		4 / 7 LEU A1197
ILE A1235
ALA A1233
ILE A1148
 None
 0.81A 1oniB-3kg9A:
undetectable
1oniC-3kg9A:
undetectable		 1oniB-3kg9A:
21.91
1oniC-3kg9A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 3kg9 CURK
(Lyngbya
majuscula) 		4 / 6 LEU A1167
ALA A1158
LEU A1163
THR A1203
 None
 1.20A 1tyrA-3kg9A:
undetectable		 1tyrA-3kg9A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3kg9 CURK
(Lyngbya
majuscula) 		4 / 8 ILE A1098
LYS A1095
LYS A1223
GLU A1234
 None
 0.94A 2j9dJ-3kg9A:
undetectable
2j9dK-3kg9A:
undetectable
2j9dL-3kg9A:
undetectable		 2j9dJ-3kg9A:
17.91
2j9dK-3kg9A:
17.91
2j9dL-3kg9A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_J_ACTJ1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3kg9 CURK
(Lyngbya
majuscula) 		4 / 8 LYS A1223
GLU A1234
ILE A1098
LYS A1095
 None
 0.98A 2j9dJ-3kg9A:
undetectable
2j9dK-3kg9A:
undetectable
2j9dL-3kg9A:
undetectable		 2j9dJ-3kg9A:
17.91
2j9dK-3kg9A:
17.91
2j9dL-3kg9A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 3kg9 CURK
(Lyngbya
majuscula) 		5 / 11 HIS A1116
ALA A1144
GLY A1180
ILE A1179
VAL A1240
 None
 1.19A 2uxpB-3kg9A:
undetectable		 2uxpB-3kg9A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 3kg9 CURK
(Lyngbya
majuscula) 		5 / 12 LEU A1010
GLY A1017
LEU A1020
GLN A1199
ILE A1204
 None
 1.12A 3ijdA-3kg9A:
undetectable		 3ijdA-3kg9A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 3kg9 CURK
(Lyngbya
majuscula) 		5 / 12 LEU A1010
GLY A1017
LEU A1020
GLN A1199
ILE A1204
 None
 1.15A 3ijdB-3kg9A:
undetectable		 3ijdB-3kg9A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_1
(ENDOTHIAPEPSIN)		 3kg9 CURK
(Lyngbya
majuscula) 		5 / 10 ILE A1034
ALA A1006
LEU A1238
ILE A1148
ILE A1204
 None
 1.11A 3prsA-3kg9A:
undetectable		 3prsA-3kg9A:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 3kg9 CURK
(Lyngbya
majuscula) 		3 / 3 PHE A1004
TYR A1161
TYR A 992
 None
 1.04A 4ffwA-3kg9A:
2.1		 4ffwA-3kg9A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3kg9 CURK
(Lyngbya
majuscula) 		5 / 11 SER A 983
GLY A 967
ALA A1015
ILE A1222
LEU A1175
 None
 1.09A 4kt0A-3kg9A:
undetectable
4kt0J-3kg9A:
undetectable		 4kt0A-3kg9A:
18.50
4kt0J-3kg9A:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3kg9 CURK
(Lyngbya
majuscula) 		5 / 12 PHE A1004
VAL A1048
PRO A1165
ILE A1194
ILE A1064
 None
 1.18A 5hbsA-3kg9A:
2.4		 5hbsA-3kg9A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)		 3kg9 CURK
(Lyngbya
majuscula) 		4 / 8 GLN A1199
LEU A1150
LEU A1167
THR A1007
 None
 1.17A 5hs6A-3kg9A:
undetectable		 5hs6A-3kg9A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_B_6J3B201_0
(TRANSTHYRETIN)		 3kg9 CURK
(Lyngbya
majuscula) 		4 / 6 LEU A1167
ALA A1158
LEU A1163
THR A1203
 None
 1.19A 5l4iB-3kg9A:
undetectable		 5l4iB-3kg9A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)		 3kg9 CURK
(Lyngbya
majuscula) 		5 / 12 GLY A1193
GLY A1084
GLU A1083
VAL A1016
ILE A1012
 None
 1.05A 5njvD-3kg9A:
undetectable		 5njvD-3kg9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_A_PA1A206_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 3kg9 CURK
(Lyngbya
majuscula) 		4 / 4 TYR A1127
GLY A1176
ASN A1181
ARG A1123
 None
 1.46A 5w7bA-3kg9A:
undetectable
5w7bC-3kg9A:
undetectable		 5w7bA-3kg9A:
13.70
5w7bC-3kg9A:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3kg9 CURK
(Lyngbya
majuscula) 		5 / 12 PHE A1004
HIS A1164
ILE A1125
LEU A 965
TYR A1161
 None
 1.40A 5ycpA-3kg9A:
undetectable		 5ycpA-3kg9A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7J_A_TESA502_0
(CYTOCHROME P450)		 3kg9 CURK
(Lyngbya
majuscula) 		4 / 7 LEU A1163
LEU A1168
ALA A1170
ALA A1171
 None
 0.88A 6a7jA-3kg9A:
undetectable		 6a7jA-3kg9A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_2
(-)		 3kg9 CURK
(Lyngbya
majuscula) 		5 / 12 LEU A 993
LEU A 985
GLY A1008
ARG A1036
PRO A1041
 None
 1.07A 6ce2B-3kg9A:
undetectable		 6ce2B-3kg9A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DK1_A_GM4A301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3kg9 CURK
(Lyngbya
majuscula) 		5 / 11 VAL A1211
ALA A1144
LEU A1238
ASP A1169
ALA A1178
 None
 1.40A 6dk1A-3kg9A:
undetectable		 6dk1A-3kg9A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DK1_C_GM4C301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3kg9 CURK
(Lyngbya
majuscula) 		5 / 11 VAL A1211
ALA A1144
LEU A1238
ASP A1169
ALA A1178
 None
 1.44A 6dk1C-3kg9A:
undetectable		 6dk1C-3kg9A:
19.93