SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kgb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
4 / 7 HIS A   7
LEU A  54
THR A  55
THR A  56
None
0.66A 1am6A-3kgbA:
undetectable
1am6A-3kgbA:
21.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 ASP A 197
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.99A 1axwA-3kgbA:
33.0
1axwA-3kgbA:
46.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AXW_B_MTXB733_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 11 ASP A 197
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.95A 1axwB-3kgbA:
33.1
1axwB-3kgbA:
46.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_A_D16A414_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
7 / 12 PHE A  60
GLU A  67
ASP A 197
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
1.06A 1hvyA-3kgbA:
36.9
1hvyA-3kgbA:
58.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_B_D16B415_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
6 / 12 GLU A  67
ASP A 197
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
1.06A 1hvyB-3kgbA:
37.1
1hvyB-3kgbA:
58.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_C_D16C416_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
7 / 11 PHE A  60
GLU A  67
ASP A 197
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
1.02A 1hvyC-3kgbA:
36.6
1hvyC-3kgbA:
58.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HVY_D_D16D417_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
6 / 12 GLU A  67
ASP A 197
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.91A 1hvyD-3kgbA:
36.9
1hvyD-3kgbA:
58.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I00_A_D16A315_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 9 PHE A  60
ASP A 197
LEU A 200
PHE A 204
TYR A 237
None
1.08A 1i00A-3kgbA:
37.2
1i00A-3kgbA:
58.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I00_A_D16A315_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
6 / 9 PHE A  60
GLU A  67
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.79A 1i00A-3kgbA:
37.2
1i00A-3kgbA:
58.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I00_B_D16B409_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 9 PHE A  60
ASP A 197
LEU A 200
GLY A 201
TYR A 237
None
1.11A 1i00B-3kgbA:
23.0
1i00B-3kgbA:
58.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I00_B_D16B409_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
6 / 9 PHE A  60
LEU A 200
GLY A 201
PHE A 204
ASN A 205
TYR A 237
None
0.75A 1i00B-3kgbA:
23.0
1i00B-3kgbA:
58.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
6 / 11 PHE A  60
ASP A 197
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
1.04A 1ju6A-3kgbA:
36.3
1ju6A-3kgbA:
56.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_C_LYAC315_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 10 ASP A 197
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
1.06A 1ju6C-3kgbA:
36.3
1ju6C-3kgbA:
56.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JU6_D_LYAD315_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 11 PHE A  60
ASP A 197
LEU A 200
GLY A 201
TYR A 237
None
0.90A 1ju6D-3kgbA:
36.3
1ju6D-3kgbA:
56.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_A_LYAA315_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 10 ASP A 197
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
1.11A 1jujA-3kgbA:
35.4
1jujA-3kgbA:
56.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_B_LYAB315_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 10 ASP A 197
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
1.11A 1jujB-3kgbA:
35.4
1jujB-3kgbA:
56.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_C_LYAC315_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 10 ASP A 197
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
1.11A 1jujC-3kgbA:
35.4
1jujC-3kgbA:
56.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JUJ_D_LYAD315_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 10 ASP A 197
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
1.11A 1jujD-3kgbA:
35.4
1jujD-3kgbA:
56.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 8 PHE A  60
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.76A 1rtsA-3kgbA:
36.9
1rtsA-3kgbA:
57.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
4 / 7 LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.68A 1rtsB-3kgbA:
36.7
1rtsB-3kgbA:
57.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_B_SALB503_1
(SALICYLIC
ACID-BINDING PROTEIN
2)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 10 LEU A 215
TRP A 118
PHE A 180
PHE A 178
LEU A  72
None
1.48A 1y7iB-3kgbA:
undetectable
1y7iB-3kgbA:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2KCE_B_D16B568_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 ASP A 197
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.86A 2kceB-3kgbA:
33.3
2kceB-3kgbA:
46.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_A_D16A309_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
4 / 7 LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.64A 2tsrA-3kgbA:
36.5
2tsrA-3kgbA:
57.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_C_D16C509_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
6 / 10 PHE A  60
GLU A  67
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.74A 2tsrC-3kgbA:
36.4
2tsrC-3kgbA:
57.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2TSR_D_D16D609_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 9 PHE A  60
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.64A 2tsrD-3kgbA:
36.4
2tsrD-3kgbA:
57.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
4 / 7 ARG A 148
GLU A 268
ARG A 119
GLU A 270
None
1.07A 2zt7A-3kgbA:
undetectable
2zt7A-3kgbA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 HIS A   7
ILE A 206
LEU A  54
THR A  55
THR A  56
None
0.93A 3fw3A-3kgbA:
undetectable
3fw3A-3kgbA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 HIS A   7
ILE A 206
LEU A  54
THR A  55
THR A  56
None
0.93A 3fw3B-3kgbA:
undetectable
3fw3B-3kgbA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
4 / 8 ALA A 145
ILE A 144
ARG A 119
PRO A 269
None
1.00A 3fxrA-3kgbA:
undetectable
3fxrA-3kgbA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
4 / 8 PRO A 251
LEU A  13
ASP A  14
LYS A  17
None
0.64A 3lsfH-3kgbA:
undetectable
3lsfH-3kgbA:
21.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NRR_A_D16A530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 GLU A  67
ASP A 197
LEU A 200
GLY A 201
TYR A 237
None
1.01A 3nrrA-3kgbA:
36.0
3nrrA-3kgbA:
31.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NRR_B_D16B530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 GLU A  67
ASP A 197
LEU A 200
GLY A 201
TYR A 237
None
1.03A 3nrrB-3kgbA:
36.1
3nrrB-3kgbA:
31.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 PHE A  70
LYS A 109
ASP A 109
GLY A 115
PHE A  71
None
1.31A 3ps9A-3kgbA:
undetectable
3ps9A-3kgbA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 10 PHE A 272
PHE A 277
ALA A 217
THR A 220
ILE A 144
None
1.23A 3t3qC-3kgbA:
undetectable
3t3qC-3kgbA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 10 PHE A 272
PHE A 277
ALA A 217
THR A 220
ILE A 144
None
1.20A 3t3qD-3kgbA:
undetectable
3t3qD-3kgbA:
23.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 HIS A 175
LEU A 200
GLY A 201
ASN A 205
TYR A 237
None
0.49A 3uwlB-3kgbA:
33.7
3uwlB-3kgbA:
45.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UWL_D_FOZD316_0
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 HIS A 175
LEU A 200
GLY A 201
ASN A 205
TYR A 237
None
0.53A 3uwlD-3kgbA:
31.5
3uwlD-3kgbA:
45.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_A_D16A402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
6 / 12 PHE A  60
ASP A 197
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
1.03A 4eb4A-3kgbA:
36.1
4eb4A-3kgbA:
58.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_A_D16A402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
6 / 12 PHE A  60
LEU A 200
GLY A 201
PHE A 204
ASN A 205
TYR A 237
None
0.80A 4eb4A-3kgbA:
36.1
4eb4A-3kgbA:
58.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_B_D16B402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
7 / 12 PHE A  60
ASP A 197
LEU A 200
GLY A 201
PHE A 204
ASN A 205
TYR A 237
None
1.00A 4eb4B-3kgbA:
36.0
4eb4B-3kgbA:
58.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_C_D16C402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
6 / 9 PHE A  60
LEU A 200
GLY A 201
PHE A 204
ASN A 205
TYR A 237
None
0.76A 4eb4C-3kgbA:
36.3
4eb4C-3kgbA:
58.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EB4_D_D16D402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
6 / 10 PHE A  60
LEU A 200
GLY A 201
PHE A 204
ASN A 205
TYR A 237
None
0.73A 4eb4D-3kgbA:
36.4
4eb4D-3kgbA:
58.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F5Z_A_BEZA302_0
(HALOALKANE
DEHALOGENASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
4 / 8 ASN A  49
ASP A  48
PHE A 259
VAL A 280
None
1.06A 4f5zA-3kgbA:
undetectable
4f5zA-3kgbA:
23.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 11 ASP A 197
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
1.03A 4fogD-3kgbA:
33.4
4fogD-3kgbA:
46.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 GLU A  67
ASP A 197
LEU A 200
GLY A 201
TYR A 237
None
0.97A 4foxA-3kgbA:
33.3
4foxA-3kgbA:
46.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_B_D16B302_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 GLU A  67
ASP A 197
LEU A 200
GLY A 201
TYR A 237
None
1.00A 4foxB-3kgbA:
33.3
4foxB-3kgbA:
46.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_C_D16C301_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 11 GLU A  67
ASP A 197
LEU A 200
GLY A 201
TYR A 237
None
1.02A 4foxC-3kgbA:
33.2
4foxC-3kgbA:
46.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_D_D16D301_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 GLU A  67
ASP A 197
LEU A 200
GLY A 201
TYR A 237
None
0.92A 4foxD-3kgbA:
33.3
4foxD-3kgbA:
46.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 GLU A  67
ASP A 197
LEU A 200
GLY A 201
TYR A 237
None
0.91A 4foxE-3kgbA:
33.3
4foxE-3kgbA:
46.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 GLU A  67
ASP A 197
LEU A 200
GLY A 201
TYR A 237
None
0.94A 4foxG-3kgbA:
33.2
4foxG-3kgbA:
46.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FQS_A_LYAA302_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 GLU A  67
ASP A 197
LEU A 200
GLY A 201
TYR A 237
None
0.88A 4fqsA-3kgbA:
33.4
4fqsA-3kgbA:
46.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 GLU A  67
ASP A 197
LEU A 200
GLY A 201
TYR A 237
None
0.88A 4fqsB-3kgbA:
33.3
4fqsB-3kgbA:
46.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
3 / 3 TYR A 274
PHE A  60
ARG A  62
None
1.08A 4g19D-3kgbA:
undetectable
4g19D-3kgbA:
21.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
4 / 7 LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.72A 4iqqA-3kgbA:
36.5
4iqqA-3kgbA:
50.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
4 / 7 LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.73A 4iqqB-3kgbA:
36.2
4iqqB-3kgbA:
50.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
4 / 7 LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.61A 4iqqC-3kgbA:
36.4
4iqqC-3kgbA:
50.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
4 / 8 LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.64A 4iqqD-3kgbA:
35.9
4iqqD-3kgbA:
50.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
4 / 5 MET A  42
LEU A 231
PRO A  52
SER A 210
None
1.30A 4kmmB-3kgbA:
undetectable
4kmmB-3kgbA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
3 / 3 ASP A 197
VAL A  37
ASN A 205
None
0.80A 4lmnA-3kgbA:
undetectable
4lmnA-3kgbA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 LEU A  72
VAL A  64
GLY A  63
SER A 208
LEU A 211
None
1.49A 4ot2A-3kgbA:
undetectable
4ot2A-3kgbA:
18.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FCT_A_C2FA402_0
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 11 PHE A  60
ASP A 197
LEU A 200
GLY A 201
TYR A 237
None
0.85A 5fctA-3kgbA:
36.8
5fctA-3kgbA:
58.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5FCT_B_C2FB402_0
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 VAL A  59
PHE A  60
CYH A 174
LEU A 200
TYR A 237
None
0.72A 5fctB-3kgbA:
36.8
5fctB-3kgbA:
58.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H3A_A_D16A401_1
(ORF70)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
4 / 7 PHE A  60
GLY A 201
PHE A 204
TYR A 237
None
0.32A 5h3aA-3kgbA:
36.8
5h3aA-3kgbA:
57.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5H3A_B_D16B401_1
(ORF70)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
4 / 7 PHE A  60
GLY A 201
PHE A 204
TYR A 237
None
0.27A 5h3aB-3kgbA:
37.1
5h3aB-3kgbA:
57.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
4 / 7 HIS A   7
LEU A  54
THR A  55
THR A  56
None
0.90A 5m78A-3kgbA:
undetectable
5m78A-3kgbA:
14.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
4 / 7 LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.74A 5nooA-3kgbA:
36.8
5nooA-3kgbA:
50.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
4 / 7 LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.76A 5nooB-3kgbA:
36.6
5nooB-3kgbA:
50.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
4 / 6 LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.74A 5nooC-3kgbA:
36.7
5nooC-3kgbA:
50.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
3 / 3 LYS A   7
HIS A  10
HIS A   7
None
1.35A 5oexA-3kgbA:
undetectable
5oexA-3kgbA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
3 / 3 LYS A   7
HIS A  10
HIS A   7
None
1.36A 5oexB-3kgbA:
undetectable
5oexB-3kgbA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
3 / 3 LYS A   7
HIS A  10
HIS A   7
None
1.36A 5oexC-3kgbA:
undetectable
5oexC-3kgbA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
3 / 3 LYS A   7
HIS A  10
HIS A   7
None
1.37A 5oexD-3kgbA:
undetectable
5oexD-3kgbA:
19.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_B_D16B402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 GLU A  67
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.80A 5x5qB-3kgbA:
36.6
5x5qB-3kgbA:
58.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 7 PHE A  60
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.74A 5x5qC-3kgbA:
36.7
5x5qC-3kgbA:
58.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 8 PHE A  60
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.77A 5x5qD-3kgbA:
36.9
5x5qD-3kgbA:
58.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
4 / 6 PHE A  60
LEU A 200
GLY A 201
TYR A 237
None
0.82A 5x5qE-3kgbA:
36.7
5x5qE-3kgbA:
58.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 8 PHE A  60
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.72A 5x5qF-3kgbA:
36.8
5x5qF-3kgbA:
58.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
6 / 12 PHE A  60
ASP A 197
LEU A 200
GLY A 201
ASN A 205
TYR A 237
None
0.84A 5x66A-3kgbA:
36.8
5x66B-3kgbA:
36.7
5x66A-3kgbA:
58.64
5x66B-3kgbA:
58.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
6 / 12 PHE A  60
LEU A 200
GLY A 201
PHE A 204
ASN A 205
TYR A 237
None
0.58A 5x66A-3kgbA:
36.8
5x66B-3kgbA:
36.7
5x66A-3kgbA:
58.64
5x66B-3kgbA:
58.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
6 / 9 ASP A 197
LEU A 200
GLY A 201
PHE A 204
ASN A 205
TYR A 237
None
0.85A 5x66C-3kgbA:
36.7
5x66C-3kgbA:
58.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_D_MTXD402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
6 / 10 PHE A  60
ASP A 197
GLY A 201
PHE A 204
ASN A 205
TYR A 237
None
0.77A 5x66D-3kgbA:
36.4
5x66D-3kgbA:
58.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5X66_F_MTXF402_1
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
6 / 12 PHE A  60
ASP A 197
LEU A 200
GLY A 201
PHE A 204
TYR A 237
None
0.88A 5x66F-3kgbA:
36.4
5x66F-3kgbA:
58.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_2
(RIFAMPIN
MONOOXYGENASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
4 / 6 GLN A  11
LEU A  54
ARG A 250
PRO A 252
None
1.12A 6brdB-3kgbA:
undetectable
6brdB-3kgbA:
16.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6QYA_D_FOZD401_0
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 HIS A 175
LEU A 200
GLY A 201
ASN A 205
TYR A 237
None
0.47A 6qyaD-3kgbA:
31.0
6qyaD-3kgbA:
45.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_A_FFOA403_0
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
6 / 12 PHE A  60
ASP A 197
GLY A 201
PHE A 204
ASN A 205
TYR A 237
None
1.06A 6r2eA-3kgbA:
36.5
6r2eA-3kgbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_A_FFOA403_0
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
6 / 12 PHE A  60
ASP A 197
LEU A 200
GLY A 201
ASN A 205
TYR A 237
None
0.77A 6r2eA-3kgbA:
36.5
6r2eA-3kgbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_B_FFOB403_0
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 10 PHE A  60
ASP A 197
LEU A 200
GLY A 201
ASN A 205
None
0.80A 6r2eB-3kgbA:
36.2
6r2eB-3kgbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_C_FFOC404_0
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 10 PHE A  60
ASP A 197
LEU A 200
GLY A 201
ASN A 205
None
0.85A 6r2eC-3kgbA:
36.3
6r2eC-3kgbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_D_FFOD403_0
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 10 PHE A  60
ASP A 197
LEU A 200
GLY A 201
ASN A 205
None
0.80A 6r2eD-3kgbA:
36.2
6r2eD-3kgbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_E_FFOE403_0
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 PHE A  60
TYR A 114
LEU A 200
GLY A 201
ASN A 205
None
0.70A 6r2eE-3kgbA:
36.1
6r2eE-3kgbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_F_FFOF403_0
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 11 PHE A  60
ASP A 197
LEU A 200
GLY A 201
ASN A 205
None
0.80A 6r2eF-3kgbA:
36.4
6r2eF-3kgbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_G_FFOG403_0
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 11 PHE A  60
ASP A 197
GLY A 201
PHE A 204
ASN A 205
None
1.18A 6r2eG-3kgbA:
36.3
6r2eG-3kgbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_G_FFOG403_0
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 11 PHE A  60
ASP A 197
LEU A 200
GLY A 201
ASN A 205
None
0.80A 6r2eG-3kgbA:
36.3
6r2eG-3kgbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_H_FFOH403_0
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 PHE A  60
ASP A 197
LEU A 200
GLY A 201
ASN A 205
None
0.85A 6r2eH-3kgbA:
36.4
6r2eH-3kgbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6R2E_H_FFOH403_0
(THYMIDYLATE SYNTHASE)
3kgb THYMIDYLATE SYNTHASE
1/2

(Encephalitozoon
cuniculi)
5 / 12 PHE A  60
TYR A 114
LEU A 200
GLY A 201
ASN A 205
None
0.82A 6r2eH-3kgbA:
36.4
6r2eH-3kgbA:
54.27