SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kgk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3kgk ARSENICAL RESISTANCE
OPERON TRANS-ACTING
REPRESSOR ARSD
(Escherichia
coli) 		5 / 12 LEU A  78
GLY A  99
ARG A  96
ALA A  95
ALA A  92
 None
 0.93A 2br4A-3kgkA:
undetectable		 2br4A-3kgkA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_C_SAMC301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3kgk ARSENICAL RESISTANCE
OPERON TRANS-ACTING
REPRESSOR ARSD
(Escherichia
coli) 		5 / 12 LEU A  78
GLY A  99
ARG A  96
ALA A  95
ALA A  92
 None
 0.89A 2br4C-3kgkA:
undetectable		 2br4C-3kgkA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3kgk ARSENICAL RESISTANCE
OPERON TRANS-ACTING
REPRESSOR ARSD
(Escherichia
coli) 		5 / 12 LEU A  78
GLY A  99
ARG A  96
ALA A  95
ALA A  92
 None
 0.90A 2br4D-3kgkA:
undetectable		 2br4D-3kgkA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3kgk ARSENICAL RESISTANCE
OPERON TRANS-ACTING
REPRESSOR ARSD
(Escherichia
coli) 		5 / 12 LEU A  78
GLY A  99
ARG A  96
ALA A  95
ALA A  92
 None
 0.96A 2br4F-3kgkA:
undetectable		 2br4F-3kgkA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3kgk ARSENICAL RESISTANCE
OPERON TRANS-ACTING
REPRESSOR ARSD
(Escherichia
coli) 		5 / 12 TYR A  88
GLY A  72
GLY A  86
ILE A  65
LEU A  48
 None
 1.02A 4iv0A-3kgkA:
undetectable		 4iv0A-3kgkA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3kgk ARSENICAL RESISTANCE
OPERON TRANS-ACTING
REPRESSOR ARSD
(Escherichia
coli) 		5 / 12 TYR A  88
GLY A  72
GLY A  86
ILE A  65
LEU A  48
 None
 1.05A 4mwzA-3kgkA:
undetectable		 4mwzA-3kgkA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_SAMB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 3kgk ARSENICAL RESISTANCE
OPERON TRANS-ACTING
REPRESSOR ARSD
(Escherichia
coli) 		5 / 12 TYR A  88
GLY A  72
GLY A  86
ILE A  65
LEU A  48
 None
 0.99A 4mwzB-3kgkA:
undetectable		 4mwzB-3kgkA:
17.36