SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kgl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)		 3kgl CRUCIFERIN
(Brassica
napus) 		5 / 11 ASP A 369
ASP A 365
VAL A 360
PRO A 338
VAL A 387
 None
 0.98A 1hxwB-3kglA:
undetectable		 1hxwB-3kglA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 3kgl CRUCIFERIN
(Brassica
napus) 		4 / 7 PHE A 368
PHE A 395
ILE A 330
ILE A 307
 None
 0.92A 2v0mB-3kglA:
undetectable		 2v0mB-3kglA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZQ9_A_CLSA11_1
(BETA-LACTAMASE
TOHO-1)		 3kgl CRUCIFERIN
(Brassica
napus) 		4 / 4 GLU A  24
ARG A 249
ASN A 248
ASP A 247
 None
 1.28A 2zq9A-3kglA:
0.5		 2zq9A-3kglA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 3kgl CRUCIFERIN
(Brassica
napus) 		4 / 8 ASP A 365
VAL A 360
PRO A 338
VAL A 387
 None
 0.71A 3nu9A-3kglA:
undetectable		 3nu9A-3kglA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 3kgl CRUCIFERIN
(Brassica
napus) 		4 / 6 ALA A 156
ILE A 317
LEU A 321
ALA A 325
 None
 0.89A 3r9sA-3kglA:
undetectable		 3r9sA-3kglA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BB2_B_STRB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3kgl CRUCIFERIN
(Brassica
napus) 		5 / 11 GLN A 163
PHE A 165
ARG A  47
ILE A 175
SER A  67
 None
 1.20A 4bb2A-3kglA:
undetectable
4bb2B-3kglA:
undetectable		 4bb2A-3kglA:
21.09
4bb2B-3kglA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3kgl CRUCIFERIN
(Brassica
napus) 		4 / 8 ASP A  32
HIS A  33
HIS A  34
HIS A  19
 None
 0.94A 5nekB-3kglA:
undetectable		 5nekB-3kglA:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3kgl CRUCIFERIN
(Brassica
napus) 		3 / 3 ASP A 362
ASN A 361
ASP A  10
 None
 0.76A 5vopA-3kglA:
undetectable		 5vopA-3kglA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3kgl CRUCIFERIN
(Brassica
napus) 		3 / 3 ASP A 362
ASN A 361
ASP A  10
 None
 0.76A 5vopB-3kglA:
undetectable		 5vopB-3kglA:
20.93