SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kgz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.76A 1v54A-3kgzA:
undetectable
1v54A-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.74A 2dyrA-3kgzA:
undetectable
2dyrA-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.73A 2dysA-3kgzA:
undetectable
2dysA-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.73A 2dysN-3kgzA:
undetectable
2dysN-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.77A 2eikN-3kgzA:
undetectable
2eikN-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.74A 2eilA-3kgzA:
undetectable
2eilA-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.76A 2eilN-3kgzA:
undetectable
2eilN-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.74A 2eimA-3kgzA:
undetectable
2eimA-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.74A 2eimN-3kgzA:
undetectable
2eimN-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.72A 2einN-3kgzA:
undetectable
2einN-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.78A 2zxwN-3kgzA:
undetectable
2zxwN-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.75A 3abkA-3kgzA:
undetectable
3abkA-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.74A 3ag1A-3kgzA:
undetectable
3ag1A-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.75A 3ag1N-3kgzA:
undetectable
3ag1N-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.76A 3ag3N-3kgzA:
undetectable
3ag3N-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.76A 3ag4N-3kgzA:
undetectable
3ag4N-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.75A 3asnA-3kgzA:
undetectable
3asnA-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.75A 3asoA-3kgzA:
undetectable
3asoA-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  78
HIS A 116
HIS A  82
MN  A   1 (-3.5A)
MN  A   1 (-3.5A)
MN  A   1 (-3.4A)
0.41A 3qpkA-3kgzA:
2.0
3qpkA-3kgzA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  78
HIS A 116
HIS A  82
MN  A   1 (-3.5A)
MN  A   1 (-3.5A)
MN  A   1 (-3.4A)
0.38A 3qpkB-3kgzA:
undetectable
3qpkB-3kgzA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.81A 3s3bA-3kgzA:
undetectable
3s3bA-3kgzA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  87
SER A  48
GLU A  66
None
0.78A 3s8pA-3kgzA:
undetectable
3s8pA-3kgzA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.73A 3x2qA-3kgzA:
undetectable
3x2qA-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  78
HIS A 116
HIS A  82
MN  A   1 (-3.5A)
MN  A   1 (-3.5A)
MN  A   1 (-3.4A)
0.42A 5migA-3kgzA:
undetectable
5migA-3kgzA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  78
ASP A 137
HIS A  80
MN  A   1 (-3.5A)
None
None
0.87A 5n1tW-3kgzA:
undetectable
5n1tW-3kgzA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA604_0
(THIOCYANATE
DEHYDROGENASE)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A 116
HIS A  82
HIS A  80
MN  A   1 (-3.5A)
MN  A   1 (-3.4A)
None
0.99A 5oexA-3kgzA:
undetectable
5oexA-3kgzA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.77A 5z84A-3kgzA:
undetectable
5z84A-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.78A 5z85A-3kgzA:
undetectable
5z85A-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.75A 5zcpA-3kgzA:
undetectable
5zcpA-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.78A 5zcpN-3kgzA:
undetectable
5zcpN-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.75A 5zcqA-3kgzA:
undetectable
5zcqA-3kgzA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3kgz CUPIN 2 CONSERVED
BARREL DOMAIN
PROTEIN

(Rhodopseudomonas
palustris)
3 / 3 HIS A  82
HIS A  78
HIS A  80
MN  A   1 (-3.4A)
MN  A   1 (-3.5A)
None
0.77A 5zcqN-3kgzA:
undetectable
5zcqN-3kgzA:
14.17