SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kh1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA6_0
(GRAMICIDIN A)		 3kh1 PREDICTED
METAL-DEPENDENT
PHOSPHOHYDROLASE
(Magnetospirillum
magnetotacticum) 		3 / 3 ALA A 164
VAL A 161
TRP A 156
 None
 0.84A 1c4dA-3kh1A:
undetectable
1c4dB-3kh1A:
undetectable		 1c4dA-3kh1A:
5.00
1c4dB-3kh1A:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 3kh1 PREDICTED
METAL-DEPENDENT
PHOSPHOHYDROLASE
(Magnetospirillum
magnetotacticum) 		3 / 3 ALA A 164
VAL A 161
TRP A 156
 None
 0.87A 1c4dC-3kh1A:
undetectable
1c4dD-3kh1A:
undetectable		 1c4dC-3kh1A:
5.00
1c4dD-3kh1A:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 3kh1 PREDICTED
METAL-DEPENDENT
PHOSPHOHYDROLASE
(Magnetospirillum
magnetotacticum) 		3 / 3 TRP A 156
ALA A 164
VAL A 161
 None
 0.80A 1c4dC-3kh1A:
undetectable
1c4dD-3kh1A:
undetectable		 1c4dC-3kh1A:
5.00
1c4dD-3kh1A:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDR_B_MTXB200_1
(DIHYDROFOLATE
REDUCTASE)		 3kh1 PREDICTED
METAL-DEPENDENT
PHOSPHOHYDROLASE
(Magnetospirillum
magnetotacticum) 		5 / 12 ILE A  47
ALA A 138
LEU A 145
ILE A  86
TYR A 125
 None
 1.22A 1ddrB-3kh1A:
undetectable		 1ddrB-3kh1A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 3kh1 PREDICTED
METAL-DEPENDENT
PHOSPHOHYDROLASE
(Magnetospirillum
magnetotacticum) 		3 / 3 GLU A  42
GLU A  38
TRP A  45
 None
 1.31A 3hrdA-3kh1A:
undetectable
3hrdE-3kh1A:
undetectable
3hrdF-3kh1A:
undetectable		 3hrdA-3kh1A:
19.39
3hrdE-3kh1A:
19.39
3hrdF-3kh1A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_1
(DIHYDROFOLATE
REDUCTASE)		 3kh1 PREDICTED
METAL-DEPENDENT
PHOSPHOHYDROLASE
(Magnetospirillum
magnetotacticum) 		5 / 12 ILE A  47
ALA A 138
LEU A 145
ILE A  86
TYR A 125
 None
 1.27A 3ia4B-3kh1A:
undetectable		 3ia4B-3kh1A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 3kh1 PREDICTED
METAL-DEPENDENT
PHOSPHOHYDROLASE
(Magnetospirillum
magnetotacticum) 		5 / 12 LEU A 180
ALA A 184
LEU A 145
LEU A 146
ILE A  47
 None
 1.07A 3q95A-3kh1A:
2.4		 3q95A-3kh1A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL0_A_FOLA160_0
(DIHYDROFOLATE
REDUCTASE)		 3kh1 PREDICTED
METAL-DEPENDENT
PHOSPHOHYDROLASE
(Magnetospirillum
magnetotacticum) 		5 / 12 ILE A  47
ALA A 138
LEU A 145
ILE A  86
TYR A 125
 None
 1.11A 3ql0A-3kh1A:
undetectable		 3ql0A-3kh1A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL3_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3kh1 PREDICTED
METAL-DEPENDENT
PHOSPHOHYDROLASE
(Magnetospirillum
magnetotacticum) 		5 / 12 ILE A  47
ALA A 138
LEU A 145
ILE A  86
TYR A 125
 None
 1.12A 3ql3A-3kh1A:
undetectable		 3ql3A-3kh1A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 3kh1 PREDICTED
METAL-DEPENDENT
PHOSPHOHYDROLASE
(Magnetospirillum
magnetotacticum) 		4 / 7 LEU A 170
GLY A 176
ALA A 138
PHE A 135
 None
 1.01A 3tehB-3kh1A:
undetectable		 3tehB-3kh1A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 3kh1 PREDICTED
METAL-DEPENDENT
PHOSPHOHYDROLASE
(Magnetospirillum
magnetotacticum) 		3 / 3 ARG A  66
MET A  70
ARG A  69
 None
 1.38A 3uvvA-3kh1A:
undetectable		 3uvvA-3kh1A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_B_MTXB201_1
(DIHYDROFOLATE
REDUCTASE)		 3kh1 PREDICTED
METAL-DEPENDENT
PHOSPHOHYDROLASE
(Magnetospirillum
magnetotacticum) 		5 / 12 ILE A  47
ALA A 138
LEU A 145
ILE A  86
TYR A 125
 None
 1.24A 4gh8B-3kh1A:
undetectable		 4gh8B-3kh1A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLF_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3kh1 PREDICTED
METAL-DEPENDENT
PHOSPHOHYDROLASE
(Magnetospirillum
magnetotacticum) 		5 / 11 ILE A  47
ALA A 138
LEU A 145
ILE A  86
TYR A 125
 None
 1.20A 4qlfA-3kh1A:
undetectable		 4qlfA-3kh1A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3kh1 PREDICTED
METAL-DEPENDENT
PHOSPHOHYDROLASE
(Magnetospirillum
magnetotacticum) 		5 / 12 ILE A  47
ALA A 138
LEU A 145
ILE A  86
TYR A 125
 None
 1.17A 4qlgA-3kh1A:
undetectable		 4qlgA-3kh1A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 3kh1 PREDICTED
METAL-DEPENDENT
PHOSPHOHYDROLASE
(Magnetospirillum
magnetotacticum) 		4 / 7 GLU A 126
TYR A 125
GLU A  78
ASP A  40
 None
 1.17A 4zz8A-3kh1A:
undetectable		 4zz8A-3kh1A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_0
(REGULATORY PROTEIN
TETR)		 3kh1 PREDICTED
METAL-DEPENDENT
PHOSPHOHYDROLASE
(Magnetospirillum
magnetotacticum) 		5 / 12 ALA A  58
GLY A 176
SER A 177
GLU A 174
LEU A 180
 None
 1.26A 5vlmF-3kh1A:
undetectable		 5vlmF-3kh1A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_0
(REGULATORY PROTEIN
TETR)		 3kh1 PREDICTED
METAL-DEPENDENT
PHOSPHOHYDROLASE
(Magnetospirillum
magnetotacticum) 		5 / 12 ALA A  58
SER A 177
GLU A 174
LEU A 180
ASP A 137
 None
 1.36A 5vlmF-3kh1A:
undetectable		 5vlmF-3kh1A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_1
(CYTOCHROME P450 2C9)		 3kh1 PREDICTED
METAL-DEPENDENT
PHOSPHOHYDROLASE
(Magnetospirillum
magnetotacticum) 		5 / 12 ALA A  41
VAL A  77
GLY A  82
ALA A  81
LEU A 106
 None
 1.09A 5xxiA-3kh1A:
undetectable		 5xxiA-3kh1A:
17.69