SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kh9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 3kh9 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Pseudomonas
aeruginosa) 		4 / 8 GLY A  62
LYS A 145
GLY A 147
LEU A 142
 None
 0.80A 1aegA-3kh9A:
undetectable		 1aegA-3kh9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 3kh9 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A 128
ILE A 143
GLU A 139
LYS A 152
ILE A 149
 None
 1.42A 1gx9A-3kh9A:
undetectable		 1gx9A-3kh9A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 3kh9 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Pseudomonas
aeruginosa) 		5 / 9 ASP A 123
GLY A 126
VAL A  69
GLY A 133
ILE A  97
 None
 0.91A 1hpvA-3kh9A:
undetectable		 1hpvA-3kh9A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 3kh9 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  66
ILE A 143
VAL A  69
LEU A 128
LEU A 132
 None
 0.94A 1s19A-3kh9A:
undetectable		 1s19A-3kh9A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 3kh9 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Pseudomonas
aeruginosa) 		5 / 11 ASP A 123
GLY A 126
VAL A  69
GLY A 133
ILE A  97
 None
 0.89A 3ekxA-3kh9A:
undetectable		 3ekxA-3kh9A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_2
(PROTEASE)		 3kh9 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 123
GLY A 126
VAL A  69
GLY A 133
ILE A  97
 None
 0.89A 3el1B-3kh9A:
undetectable		 3el1B-3kh9A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 3kh9 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Pseudomonas
aeruginosa) 		5 / 9 ASP A 123
GLY A 126
VAL A  69
GLY A 133
ILE A  97
 None
 0.96A 3oxvC-3kh9A:
undetectable		 3oxvC-3kh9A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3kh9 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  65
ALA A  58
PHE A  40
ILE A  97
LEU A 128
 None
 1.03A 4kjjA-3kh9A:
undetectable		 4kjjA-3kh9A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_2
(PROTEASE)		 3kh9 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Pseudomonas
aeruginosa) 		5 / 11 ASP A 123
GLY A 126
VAL A  69
GLY A 133
ILE A  97
 None
 0.92A 4njvB-3kh9A:
undetectable		 4njvB-3kh9A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_1
(PROTEASE)		 3kh9 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Pseudomonas
aeruginosa) 		5 / 11 ASP A 123
GLY A 126
VAL A  69
GLY A 133
ILE A  97
 None
 0.93A 4njvC-3kh9A:
undetectable		 4njvC-3kh9A:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSY_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3kh9 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  65
ALA A  58
PHE A  40
ILE A  97
LEU A 128
 None
 1.00A 4psyA-3kh9A:
undetectable		 4psyA-3kh9A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 3kh9 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Pseudomonas
aeruginosa) 		4 / 8 LEU A 130
GLY A 129
GLU A 139
ALA A 137
 None
 0.86A 4rjdA-3kh9A:
undetectable
4rjdB-3kh9A:
undetectable		 4rjdA-3kh9A:
13.14
4rjdB-3kh9A:
13.14