SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3khf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 3khf MICROTUBULE-ASSOCIAT
ED
SERINE/THREONINE-PRO
TEIN KINASE 3
(Homo
sapiens) 		5 / 10 LEU A1023
VAL A1019
ILE A1006
LEU A 997
VAL A 983
 None
 1.19A 1cqpA-3khfA:
undetectable
1cqpB-3khfA:
undetectable		 1cqpA-3khfA:
20.35
1cqpB-3khfA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3khf MICROTUBULE-ASSOCIAT
ED
SERINE/THREONINE-PRO
TEIN KINASE 3
(Homo
sapiens) 		5 / 10 GLY A1027
LEU A1032
LEU A1023
ASN A1007
ILE A1006
 None
 1.20A 3wdmB-3khfA:
undetectable		 3wdmB-3khfA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3khf MICROTUBULE-ASSOCIAT
ED
SERINE/THREONINE-PRO
TEIN KINASE 3
(Homo
sapiens) 		5 / 9 GLY A1027
LEU A1032
LEU A1023
ASN A1007
ILE A1006
 None
 1.19A 3wdmC-3khfA:
undetectable		 3wdmC-3khfA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3khf MICROTUBULE-ASSOCIAT
ED
SERINE/THREONINE-PRO
TEIN KINASE 3
(Homo
sapiens) 		5 / 10 GLY A1027
LEU A1032
LEU A1023
ASN A1007
ILE A1006
 None
 1.15A 3wdmD-3khfA:
undetectable		 3wdmD-3khfA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 3khf MICROTUBULE-ASSOCIAT
ED
SERINE/THREONINE-PRO
TEIN KINASE 3
(Homo
sapiens) 		4 / 4 LEU A1002
ILE A 967
HIS A 980
VAL A 982
 None
 1.30A 4xyzA-3khfA:
undetectable		 4xyzA-3khfA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3khf MICROTUBULE-ASSOCIAT
ED
SERINE/THREONINE-PRO
TEIN KINASE 3
(Homo
sapiens) 		5 / 12 VAL A 979
LEU A1023
HIS A 981
LEU A 964
ALA A 966
 None
 1.20A 5nd3B-3khfA:
undetectable		 5nd3B-3khfA:
14.05