SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3khn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_B_IBPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 11 VAL A 116
VAL A  49
SER A  51
ALA A  66
LEU A  70
 None
 1.10A 1eqgB-3khnA:
undetectable		 1eqgB-3khnA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_A_FLPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A 116
VAL A  49
GLY A  65
ALA A  66
LEU A  70
 None
 0.89A 1eqhA-3khnA:
undetectable		 1eqhA-3khnA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A 116
VAL A  49
GLY A  65
ALA A  66
LEU A  70
 None
 0.90A 1eqhB-3khnA:
undetectable		 1eqhB-3khnA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		4 / 8 ASN A 153
ARG A  48
GLU A 157
PHE A  90
 None
 0.94A 2fl5E-3khnA:
undetectable
2fl5F-3khnA:
undetectable		 2fl5E-3khnA:
20.92
2fl5F-3khnA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGQ_A_PCFA1275_0
(WNT INHIBITORY
FACTOR 1)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 LEU A 160
ILE A  87
ILE A  85
PHE A 158
PHE A  27
 None
 0.97A 2ygqA-3khnA:
undetectable		 2ygqA-3khnA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		4 / 8 GLY A  89
VAL A  44
SER A 113
THR A 131
 None
 0.91A 2yoeB-3khnA:
undetectable
2yoeC-3khnA:
undetectable		 2yoeB-3khnA:
21.09
2yoeC-3khnA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 9 ILE A  36
GLY A  37
SER A  51
LEU A  54
GLU A 157
 None
 0.86A 3ai9X-3khnA:
undetectable		 3ai9X-3khnA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A 116
VAL A  49
SER A  51
GLY A  65
ALA A  66
 None
 0.99A 3hs6A-3khnA:
undetectable		 3hs6A-3khnA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A  49
SER A  51
GLY A  65
ALA A  66
LEU A  70
 None
 0.83A 3ln1D-3khnA:
undetectable		 3ln1D-3khnA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8W_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A 116
VAL A  49
GLY A  65
ALA A  66
LEU A  70
 None
 0.87A 3n8wA-3khnA:
undetectable		 3n8wA-3khnA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A 116
VAL A  49
GLY A  65
ALA A  66
LEU A  70
 None
 0.88A 3n8zA-3khnA:
undetectable		 3n8zA-3khnA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A 116
VAL A  49
GLY A  65
ALA A  66
LEU A  70
 None
 0.89A 3pghC-3khnA:
undetectable		 3pghC-3khnA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_A_FLRA700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A 116
VAL A  49
GLY A  65
ALA A  66
LEU A  70
 None
 0.92A 3rr3A-3khnA:
undetectable		 3rr3A-3khnA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_B_FLRB700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A 116
VAL A  49
GLY A  65
ALA A  66
LEU A  70
 None
 0.93A 3rr3B-3khnA:
undetectable		 3rr3B-3khnA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_A_IMNA701_1
(CYCLOOXYGENASE-2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A  49
SER A  51
GLY A  65
ALA A  66
LEU A  70
 None
 0.80A 4coxA-3khnA:
undetectable		 4coxA-3khnA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_B_IMNB701_1
(CYCLOOXYGENASE-2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A  49
SER A  51
GLY A  65
ALA A  66
LEU A  70
 None
 0.82A 4coxB-3khnA:
undetectable		 4coxB-3khnA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_C_IMNC701_1
(CYCLOOXYGENASE-2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A  49
SER A  51
GLY A  65
ALA A  66
LEU A  70
 None
 0.82A 4coxC-3khnA:
undetectable		 4coxC-3khnA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A  49
SER A  51
GLY A  65
ALA A  66
LEU A  70
 None
 0.82A 4coxD-3khnA:
undetectable		 4coxD-3khnA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ4_A_IMNA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 10 VAL A  35
VAL A  53
TYR A  26
LEU A  76
LEU A  73
 None
 1.48A 4jq4A-3khnA:
undetectable		 4jq4A-3khnA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		4 / 6 THR A  72
LEU A 160
LEU A 130
GLU A 126
 None
 1.13A 4nc3A-3khnA:
undetectable		 4nc3A-3khnA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A  49
SER A  51
GLY A  65
ALA A  66
LEU A  70
 None
 0.80A 4otyA-3khnA:
undetectable		 4otyA-3khnA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A  49
SER A  51
GLY A  65
ALA A  66
LEU A  70
 None
 0.81A 4otyB-3khnA:
undetectable		 4otyB-3khnA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 10 VAL A 116
VAL A  49
GLY A  65
ALA A  66
LEU A  70
 None
 0.94A 4ph9A-3khnA:
undetectable		 4ph9A-3khnA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 10 VAL A 116
VAL A  49
GLY A  65
ALA A  66
LEU A  70
 None
 0.93A 4ph9B-3khnA:
undetectable		 4ph9B-3khnA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 9 VAL A  49
SER A  51
GLY A  65
ALA A  66
LEU A  70
 None
 0.87A 4rs0A-3khnA:
undetectable		 4rs0A-3khnA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A  49
SER A  51
GLY A  65
ALA A  66
LEU A  70
 None
 0.80A 5ikrA-3khnA:
undetectable		 5ikrA-3khnA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		6 / 12 VAL A 116
VAL A  49
SER A  51
GLY A  65
ALA A  66
LEU A  70
 None
 0.98A 5iktA-3khnA:
undetectable		 5iktA-3khnA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A 116
SER A  51
GLY A  65
ALA A  66
LEU A  70
 None
 0.79A 5iktB-3khnA:
undetectable		 5iktB-3khnA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A 116
VAL A  49
GLY A  65
ALA A  66
LEU A  70
 None
 0.83A 5iktB-3khnA:
undetectable		 5iktB-3khnA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_B_FLPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A  49
SER A  51
GLY A  65
ALA A  66
LEU A  70
 None
 0.86A 5jvzB-3khnA:
undetectable		 5jvzB-3khnA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3khn MOTB PROTEIN,
PUTATIVE
(Desulfovibrio
vulgaris) 		5 / 12 VAL A  49
SER A  51
GLY A  65
ALA A  66
LEU A  70
 None
 0.81A 5kirB-3khnA:
undetectable		 5kirB-3khnA:
16.26