SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ki6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMA_A_NCAA700_0
(EXOTOXIN A)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		6 / 7 HIS A 460
GLY A 461
TYR A 493
ALA A 501
TYR A 504
GLU A 581
 G9L  A   1 (-3.9A)
G9L  A   1 (-3.7A)
G9L  A   1 (-4.5A)
G9L  A   1 (-3.4A)
G9L  A   1 (-3.5A)
G9L  A   1 (-4.6A)
 0.27A 1dmaA-3ki6A:
25.3		 1dmaA-3ki6A:
40.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMA_B_NCAB700_0
(EXOTOXIN A)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		6 / 6 HIS A 460
GLY A 461
TYR A 493
ALA A 495
TYR A 504
GLU A 581
 G9L  A   1 (-3.9A)
G9L  A   1 (-3.7A)
G9L  A   1 (-4.5A)
G9L  A   1 (-3.4A)
G9L  A   1 (-3.5A)
G9L  A   1 (-4.6A)
 0.42A 1dmaB-3ki6A:
23.1		 1dmaB-3ki6A:
40.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		3 / 3 VAL A 465
ALA A 466
HIS A 460
 None
None
G9L  A   1 (-3.9A)
 0.71A 1q23C-3ki6A:
undetectable		 1q23C-3ki6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		3 / 3 VAL A 465
ALA A 466
HIS A 460
 None
None
G9L  A   1 (-3.9A)
 0.70A 1q23H-3ki6A:
undetectable		 1q23H-3ki6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		3 / 3 VAL A 465
ALA A 466
HIS A 460
 None
None
G9L  A   1 (-3.9A)
 0.64A 1q23G-3ki6A:
undetectable		 1q23G-3ki6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		3 / 3 VAL A 465
ALA A 466
HIS A 460
 None
None
G9L  A   1 (-3.9A)
 0.69A 1q23J-3ki6A:
undetectable		 1q23J-3ki6A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1353_1
(PROSTAGLANDIN
REDUCTASE 2)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		5 / 9 THR A 582
PHE A 570
GLU A 581
VAL A 494
GLY A 585
 None
None
G9L  A   1 (-4.6A)
None
None
 1.42A 2w98A-3ki6A:
undetectable		 2w98A-3ki6A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		4 / 6 PHE A 541
TYR A 626
THR A 496
VAL A 494
 None
 1.29A 3lb3B-3ki6A:
undetectable		 3lb3B-3ki6A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_2
(HIV-1 PROTEASE)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		5 / 12 LEU A 529
ALA A 592
VAL A 457
GLY A 585
VAL A 531
 None
 0.97A 3so9B-3ki6A:
undetectable		 3so9B-3ki6A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		5 / 8 HIS A 460
GLY A 461
TYR A 493
ALA A 495
TYR A 504
 G9L  A   1 (-3.9A)
G9L  A   1 (-3.7A)
G9L  A   1 (-4.5A)
G9L  A   1 (-3.4A)
G9L  A   1 (-3.5A)
 0.38A 3u9hA-3ki6A:
5.7		 3u9hA-3ki6A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		4 / 8 HIS A 460
GLY A 461
TYR A 504
GLU A 581
 G9L  A   1 (-3.9A)
G9L  A   1 (-3.7A)
G9L  A   1 (-3.5A)
G9L  A   1 (-4.6A)
 0.77A 3u9hA-3ki6A:
5.7		 3u9hA-3ki6A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		5 / 8 HIS A 460
GLY A 461
TYR A 493
ALA A 495
TYR A 504
 G9L  A   1 (-3.9A)
G9L  A   1 (-3.7A)
G9L  A   1 (-4.5A)
G9L  A   1 (-3.4A)
G9L  A   1 (-3.5A)
 0.43A 3u9hB-3ki6A:
5.7		 3u9hB-3ki6A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		4 / 8 HIS A 460
GLY A 461
TYR A 504
GLU A 581
 G9L  A   1 (-3.9A)
G9L  A   1 (-3.7A)
G9L  A   1 (-3.5A)
G9L  A   1 (-4.6A)
 0.71A 3u9hB-3ki6A:
5.7		 3u9hB-3ki6A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		6 / 6 HIS A 460
GLY A 461
TYR A 493
ALA A 501
TYR A 504
GLU A 581
 G9L  A   1 (-3.9A)
G9L  A   1 (-3.7A)
G9L  A   1 (-4.5A)
G9L  A   1 (-3.4A)
G9L  A   1 (-3.5A)
G9L  A   1 (-4.6A)
 0.55A 4ae1A-3ki6A:
8.8		 4ae1A-3ki6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_B_NCAB1536_0
(DIPHTHERIA TOXIN)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		5 / 5 HIS A 460
GLY A 461
TYR A 493
TYR A 504
GLU A 581
 G9L  A   1 (-3.9A)
G9L  A   1 (-3.7A)
G9L  A   1 (-4.5A)
G9L  A   1 (-3.5A)
G9L  A   1 (-4.6A)
 0.51A 4ae1B-3ki6A:
8.2		 4ae1B-3ki6A:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		5 / 8 HIS A 460
GLY A 461
TYR A 493
ALA A 495
TYR A 504
 G9L  A   1 (-3.9A)
G9L  A   1 (-3.7A)
G9L  A   1 (-4.5A)
G9L  A   1 (-3.4A)
G9L  A   1 (-3.5A)
 0.35A 4bjcA-3ki6A:
5.2		 4bjcA-3ki6A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		4 / 8 HIS A 460
GLY A 461
TYR A 504
GLU A 581
 G9L  A   1 (-3.9A)
G9L  A   1 (-3.7A)
G9L  A   1 (-3.5A)
G9L  A   1 (-4.6A)
 0.67A 4bjcA-3ki6A:
5.2		 4bjcA-3ki6A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		6 / 7 HIS A 460
GLY A 461
TYR A 493
ALA A 495
TYR A 504
GLU A 581
 G9L  A   1 (-3.9A)
G9L  A   1 (-3.7A)
G9L  A   1 (-4.5A)
G9L  A   1 (-3.4A)
G9L  A   1 (-3.5A)
G9L  A   1 (-4.6A)
 0.59A 4hyfA-3ki6A:
5.8		 4hyfA-3ki6A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		6 / 8 HIS A 460
GLY A 461
TYR A 493
ALA A 495
TYR A 504
GLU A 581
 G9L  A   1 (-3.9A)
G9L  A   1 (-3.7A)
G9L  A   1 (-4.5A)
G9L  A   1 (-3.4A)
G9L  A   1 (-3.5A)
G9L  A   1 (-4.6A)
 0.61A 4hyfB-3ki6A:
5.7		 4hyfB-3ki6A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		6 / 8 HIS A 460
GLY A 461
TYR A 493
ALA A 495
TYR A 504
GLU A 581
 G9L  A   1 (-3.9A)
G9L  A   1 (-3.7A)
G9L  A   1 (-4.5A)
G9L  A   1 (-3.4A)
G9L  A   1 (-3.5A)
G9L  A   1 (-4.6A)
 0.55A 4hyfC-3ki6A:
5.6		 4hyfC-3ki6A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		5 / 11 GLY A 458
VAL A 494
PRO A 624
PHE A 541
ILE A 533
 None
 1.03A 4j4vA-3ki6A:
undetectable		 4j4vA-3ki6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		4 / 8 GLY A 458
PRO A 624
PHE A 541
ILE A 533
 None
 0.65A 4j4vC-3ki6A:
undetectable		 4j4vC-3ki6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_D_SVRD301_1
(NUCLEOCAPSID PROTEIN)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		5 / 11 GLY A 458
VAL A 494
PRO A 624
PHE A 541
ILE A 533
 None
 1.17A 4j4vD-3ki6A:
undetectable
4j4vE-3ki6A:
undetectable		 4j4vD-3ki6A:
20.85
4j4vE-3ki6A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		4 / 6 ASN A 602
GLU A 605
TYR A 604
GLU A 606
 None
 1.35A 4mi4A-3ki6A:
undetectable		 4mi4A-3ki6A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		4 / 7 ASN A 602
GLU A 605
TYR A 604
GLU A 606
 None
 1.37A 4mj8C-3ki6A:
undetectable		 4mj8C-3ki6A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RV6_A_RPBA1103_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		6 / 11 HIS A 460
GLY A 461
TYR A 493
ALA A 495
TYR A 504
GLU A 581
 G9L  A   1 (-3.9A)
G9L  A   1 (-3.7A)
G9L  A   1 (-4.5A)
G9L  A   1 (-3.4A)
G9L  A   1 (-3.5A)
G9L  A   1 (-4.6A)
 0.45A 4rv6A-3ki6A:
5.5		 4rv6A-3ki6A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RV6_B_RPBB1103_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		6 / 11 HIS A 460
GLY A 461
TYR A 493
ALA A 495
TYR A 504
GLU A 581
 G9L  A   1 (-3.9A)
G9L  A   1 (-3.7A)
G9L  A   1 (-4.5A)
G9L  A   1 (-3.4A)
G9L  A   1 (-3.5A)
G9L  A   1 (-4.6A)
 0.44A 4rv6B-3ki6A:
5.6		 4rv6B-3ki6A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		3 / 3 LEU A 442
TYR A 532
SER A 621
 None
 0.89A 5iktA-3ki6A:
undetectable		 5iktA-3ki6A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		3 / 3 SER A 621
HIS A 446
TYR A 532
 None
 1.00A 5y2tA-3ki6A:
undetectable		 5y2tA-3ki6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)		 3ki6 CHOLIX TOXIN
(Vibrio
cholerae) 		4 / 5 TYR A 626
VAL A 593
PHE A 570
GLY A 572
 None
 1.34A 6hd4A-3ki6A:
undetectable		 6hd4A-3ki6A:
17.54