SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kie'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		3 / 3 TRP A 279
TYR A 281
LEU A 249
 None
 1.10A 1kxhA-3kieA:
undetectable		 1kxhA-3kieA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 8 SER A 390
ASN A 381
GLN A 385
PHE A 273
 None
 1.20A 1p6kA-3kieA:
undetectable		 1p6kA-3kieA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 8 SER A 390
ASN A 381
GLN A 385
PHE A 273
 None
 1.19A 1p6kB-3kieA:
undetectable		 1p6kB-3kieA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 8 SER A 390
ASN A 381
GLN A 385
PHE A 273
 None
 1.18A 1rs6A-3kieA:
undetectable		 1rs6A-3kieA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 8 SER A 390
ASN A 381
GLN A 385
PHE A 273
 None
 1.19A 1rs6B-3kieA:
undetectable		 1rs6B-3kieA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 8 SER A 390
ASN A 381
GLN A 385
PHE A 273
 None
 1.15A 1rs7B-3kieA:
undetectable		 1rs7B-3kieA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		5 / 10 GLY A 637
THR A 729
VAL A 612
GLU A 563
SER A 632
 None
None
None
None
D5M  A 999 ( 3.9A)
 1.07A 1z35A-3kieA:
undetectable		 1z35A-3kieA:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 8 SER A 390
ASN A 381
GLN A 385
PHE A 273
 None
 1.18A 1zzqA-3kieA:
undetectable		 1zzqA-3kieA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 8 SER A 390
ASN A 381
GLN A 385
PHE A 273
 None
 1.19A 1zzqB-3kieA:
undetectable		 1zzqB-3kieA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 8 SER A 390
ASN A 381
GLN A 385
PHE A 273
 None
 1.16A 1zzuA-3kieA:
undetectable		 1zzuA-3kieA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 8 SER A 390
ASN A 381
GLN A 385
PHE A 273
 None
 1.19A 1zzuB-3kieA:
undetectable		 1zzuB-3kieA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		3 / 3 TRP A 279
GLN A 646
TRP A 247
 None
 1.28A 2vqyA-3kieA:
undetectable		 2vqyA-3kieA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 5 ARG A 730
LEU A 299
ILE A 618
PHE A 287
 None
 1.27A 3ln1D-3kieA:
undetectable		 3ln1D-3kieA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 8 SER A 390
ASN A 381
GLN A 385
PHE A 273
 None
 1.21A 3n62B-3kieA:
undetectable		 3n62B-3kieA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		3 / 3 HIS A 229
SER A 312
GLU A 682
 None
 0.85A 3s8pA-3kieA:
undetectable		 3s8pA-3kieA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_A_DM2A1106_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		5 / 11 PHE A 287
PHE A 306
ASN A 303
LEU A 299
GLN A 608
 None
 1.48A 4dx7A-3kieA:
undetectable		 4dx7A-3kieA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7B_C_ACTC513_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		3 / 3 TYR A 424
HIS A 426
ARG A 734
 None
 0.95A 4e7bC-3kieA:
undetectable		 4e7bC-3kieA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		5 / 12 LEU A 354
GLN A 646
VAL A 353
GLY A 360
THR A 277
 None
 0.88A 4m2vA-3kieA:
undetectable		 4m2vA-3kieA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		3 / 3 CYH A 289
PRO A 617
ASP A 283
 None
 0.98A 4pm5A-3kieA:
undetectable		 4pm5A-3kieA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 308
PHE A 638
TRP A 619
TYR A 352
 None
 1.40A 4v2yA-3kieA:
undetectable		 4v2yA-3kieA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_A_Y70A151_1
(CEREBLON ISOFORM 4)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 308
PHE A 638
TRP A 619
TYR A 352
 None
 1.44A 4v2zA-3kieA:
undetectable		 4v2zA-3kieA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 8 PRO A 308
PHE A 638
TRP A 619
TYR A 352
 None
 1.38A 4v2zB-3kieA:
undetectable		 4v2zB-3kieA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_A_LVYA151_1
(CEREBLON ISOFORM 4)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 308
PHE A 638
TRP A 619
TYR A 352
 None
 1.42A 4v30A-3kieA:
undetectable		 4v30A-3kieA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 8 PRO A 308
PHE A 638
TRP A 619
TYR A 352
 None
 1.28A 4v30B-3kieA:
undetectable		 4v30B-3kieA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 6 LEU A 350
TYR A 352
PRO A 351
TYR A 375
 None
 1.31A 4z4gA-3kieA:
undetectable		 4z4gA-3kieA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 HIS A 229
LYS A 314
GLY A 226
ASN A 227
 None
 1.21A 5a5zC-3kieA:
undetectable		 5a5zC-3kieA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_A_EF2A151_1
(CEREBLON ISOFORM 4)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 308
PHE A 638
TRP A 619
TYR A 352
 None
 1.41A 5amiA-3kieA:
undetectable		 5amiA-3kieA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 8 PRO A 308
PHE A 638
TRP A 619
TYR A 352
 None
 1.43A 5amiB-3kieA:
undetectable		 5amiB-3kieA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_B_EF2B151_1
(CEREBLON ISOFORM 4)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 308
PHE A 638
TRP A 619
TYR A 352
 None
 1.38A 5amjB-3kieA:
undetectable		 5amjB-3kieA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_B_EF2B151_1
(CEREBLON ISOFORM 4)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 308
PHE A 638
TRP A 619
TYR A 352
 None
 1.36A 5amkB-3kieA:
undetectable		 5amkB-3kieA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_A_EF2A202_0
(CEREBLON ISOFORM 4)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 308
PHE A 638
TRP A 619
TYR A 352
 None
 1.42A 5oh1A-3kieA:
0.0		 5oh1A-3kieA:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 308
PHE A 638
TRP A 619
TYR A 352
 None
 1.35A 5oh1B-3kieA:
undetectable		 5oh1B-3kieA:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_A_9V2A202_0
(CEREBLON ISOFORM 4)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 308
PHE A 638
TRP A 619
TYR A 352
 None
 1.42A 5oh3A-3kieA:
undetectable		 5oh3A-3kieA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_B_9V2B202_0
(CEREBLON ISOFORM 4)		 3kie CAPSID PROTEIN VP1
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 308
PHE A 638
TRP A 619
TYR A 352
 None
 1.39A 5oh3B-3kieA:
undetectable		 5oh3B-3kieA:
10.69