SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kij'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 3kij PROBABLE GLUTATHIONE
PEROXIDASE 8
(Homo
sapiens) 		4 / 7 PHE A 151
PRO A 162
PHE A 111
TRP A 167
 None
 1.28A 1lqtA-3kijA:
3.1		 1lqtA-3kijA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 3kij PROBABLE GLUTATHIONE
PEROXIDASE 8
(Homo
sapiens) 		4 / 7 PHE A 151
PRO A 162
PHE A 111
TRP A 167
 None
 1.26A 1lquA-3kijA:
3.1		 1lquA-3kijA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 3kij PROBABLE GLUTATHIONE
PEROXIDASE 8
(Homo
sapiens) 		4 / 7 THR A  82
TYR A  86
ASN A  74
LEU A  89
 None
 1.09A 1qzrA-3kijA:
undetectable		 1qzrA-3kijA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)		 3kij PROBABLE GLUTATHIONE
PEROXIDASE 8
(Homo
sapiens) 		4 / 7 THR A  82
TYR A  86
ASN A  74
LEU A  89
 None
 1.10A 1qzrB-3kijA:
undetectable		 1qzrB-3kijA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3kij PROBABLE GLUTATHIONE
PEROXIDASE 8
(Homo
sapiens) 		5 / 12 SER A  99
PHE A 101
PRO A 135
LEU A  62
SER A  70
 None
 1.00A 2fj1A-3kijA:
undetectable		 2fj1A-3kijA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1499_1
(CYTOCHROME P450 3A4)		 3kij PROBABLE GLUTATHIONE
PEROXIDASE 8
(Homo
sapiens) 		4 / 5 PHE A  47
PHE A 134
PHE A 106
ILE A 187
 None
 1.26A 2v0mD-3kijA:
undetectable		 2v0mD-3kijA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3kij PROBABLE GLUTATHIONE
PEROXIDASE 8
(Homo
sapiens) 		4 / 7 PHE A  47
SER A 157
VAL A 155
VAL A 177
 None
 1.31A 3n61A-3kijA:
undetectable
3n61B-3kijA:
undetectable		 3n61A-3kijA:
18.75
3n61B-3kijA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 3kij PROBABLE GLUTATHIONE
PEROXIDASE 8
(Homo
sapiens) 		4 / 7 PHE A 125
ASN A 109
ALA A  76
THR A  82
 None
 0.88A 3t3sC-3kijA:
undetectable		 3t3sC-3kijA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3kij PROBABLE GLUTATHIONE
PEROXIDASE 8
(Homo
sapiens) 		5 / 12 VAL A 122
ALA A  55
LEU A  71
VAL A  72
VAL A 132
 None
 1.16A 4ib4A-3kijA:
undetectable		 4ib4A-3kijA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3kij PROBABLE GLUTATHIONE
PEROXIDASE 8
(Homo
sapiens) 		4 / 7 ALA A 105
TYR A  86
VAL A 122
GLU A 115
 None
 1.05A 5ecnA-3kijA:
undetectable		 5ecnA-3kijA:
15.66