SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kkd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 3kkd TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		5 / 12 THR A 200
LEU A 199
ILE A 203
VAL A 138
LEU A 231
 PGE  A 238 ( 4.5A)
None
PGE  A 238 ( 4.6A)
None
None
 1.32A 1wsvA-3kkdA:
undetectable		 1wsvA-3kkdA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 3kkd TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		5 / 12 THR A 200
LEU A 199
ILE A 203
VAL A 138
LEU A 231
 PGE  A 238 ( 4.5A)
None
PGE  A 238 ( 4.6A)
None
None
 1.33A 1wsvB-3kkdA:
undetectable		 1wsvB-3kkdA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_B_CL6B506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3kkd TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  82
LEU A  47
ALA A  62
GLU A  64
ALA A  39
 None
 0.95A 3mdvB-3kkdA:
undetectable		 3mdvB-3kkdA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 3kkd TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		3 / 3 GLU A 132
ARG A 129
GLN A 139
 None
 0.96A 4rtbA-3kkdA:
undetectable		 4rtbA-3kkdA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3kkd TRANSCRIPTIONAL
REGULATOR
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  61
LEU A 165
ASP A  80
ALA A  44
GLN A 157
 None
 1.39A 5syfB-3kkdA:
undetectable		 5syfB-3kkdA:
19.29