SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kkf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 3kkf PUTATIVE ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ASP A 120
GLU A  85
SER A  36
LEU A 118
 None
ACT  A 203 ( 3.9A)
P6G  A 206 ( 4.9A)
None
 1.05A 2q0iA-3kkfA:
undetectable		 2q0iA-3kkfA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3kkf PUTATIVE ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A  79
ASN A  49
GLU A  46
 None
 0.93A 3kpdB-3kkfA:
undetectable		 3kpdB-3kkfA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3kkf PUTATIVE ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LYS A 106
ARG A  34
LEU A 116
 P6G  A 206 (-2.7A)
P6G  A 206 ( 4.6A)
P6G  A 206 (-4.0A)
 1.11A 3v4tE-3kkfA:
undetectable		 3v4tE-3kkfA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IOM_A_FOLA608_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 3kkf PUTATIVE ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ALA A  71
GLU A  55
LEU A  52
TYR A  48
 None
ACT  A 203 (-2.4A)
None
None
 1.05A 4iomA-3kkfA:
undetectable		 4iomA-3kkfA:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 3kkf PUTATIVE ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A  55
TYR A  87
GLU A  85
 ACT  A 203 (-2.4A)
None
ACT  A 203 ( 3.9A)
 0.82A 4ryaA-3kkfA:
undetectable		 4ryaA-3kkfA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3kkf PUTATIVE ANTIBIOTIC
BIOSYNTHESIS
MONOOXYGENASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A  69
ILE A  56
TYR A  48
 ACT  A 203 ( 4.6A)
None
None
 0.62A 5uunB-3kkfA:
undetectable		 5uunB-3kkfA:
17.06