SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kkj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 4 VAL A  78
TRP A  81
TRP A 103
 None
 1.34A 1gmkA-3kkjA:
undetectable
1gmkB-3kkjA:
undetectable		 1gmkA-3kkjA:
4.19
1gmkB-3kkjA:
4.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_1
(HIV-1 PROTEASE)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 GLY A  54
ALA A  55
ILE A  12
GLY A  11
GLY A  38
 FAD  A 401 (-3.7A)
FAD  A 401 (-3.5A)
None
FAD  A 401 (-2.9A)
None
 0.85A 1hxbA-3kkjA:
undetectable		 1hxbA-3kkjA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA733_1
(ALPHA AMYLASE)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 SER A 218
ASN A 216
LEU A  51
ASP A  52
 None
 1.28A 1mxdA-3kkjA:
undetectable		 1mxdA-3kkjA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 PHE A 270
LEU A 226
GLY A  49
ASP A 223
 None
 0.85A 1rmtC-3kkjA:
undetectable		 1rmtC-3kkjA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_1
(POL POLYPROTEIN)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 GLY A  54
ALA A  55
ILE A  12
GLY A  11
GLY A  38
 FAD  A 401 (-3.7A)
FAD  A 401 (-3.5A)
None
FAD  A 401 (-2.9A)
None
 0.80A 2avvD-3kkjA:
undetectable		 2avvD-3kkjA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 ILE A  12
SER A  16
PHE A  65
PHE A  58
 None
 1.18A 2qb4A-3kkjA:
undetectable		 2qb4A-3kkjA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 GLN A  75
THR A  67
TRP A 313
 None
 1.15A 2rctA-3kkjA:
undetectable		 2rctA-3kkjA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_B_X2NB1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 PHE A 192
MET A 265
PRO A 268
ALA A 256
LEU A 231
 None
 1.26A 2x2nB-3kkjA:
undetectable		 2x2nB-3kkjA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_C_X2NC1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 PHE A 192
MET A 265
PRO A 268
ALA A 256
LEU A 231
 None
 1.29A 2x2nC-3kkjA:
undetectable		 2x2nC-3kkjA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 VAL A  69
ILE A  12
ARG A 117
LEU A  30
 None
 0.86A 3bjwB-3kkjA:
undetectable		 3bjwB-3kkjA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 VAL A  69
GLY A  14
ARG A 117
LEU A  30
 None
 1.09A 3bjwE-3kkjA:
undetectable		 3bjwE-3kkjA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 VAL A  69
ILE A  12
ARG A 117
LEU A  30
 None
 0.91A 3bjwF-3kkjA:
undetectable		 3bjwF-3kkjA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 VAL A  69
ILE A  12
GLY A  11
ARG A 117
 None
None
FAD  A 401 (-2.9A)
None
 0.92A 3bjwF-3kkjA:
undetectable		 3bjwF-3kkjA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 VAL A  69
ILE A  12
ARG A 117
LEU A  30
 None
 0.87A 3bjwH-3kkjA:
undetectable		 3bjwH-3kkjA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 VAL A  69
ILE A  12
GLY A  11
ARG A 117
 None
None
FAD  A 401 (-2.9A)
None
 0.93A 3bjwH-3kkjA:
undetectable		 3bjwH-3kkjA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_B_KKKB413_1
(FLAVOHEMOGLOBIN)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 ILE A   5
ALA A  17
LEU A  21
LEU A 327
GLY A 301
 None
None
None
None
FAD  A 401 (-3.4A)
 1.11A 3ozwB-3kkjA:
4.3		 3ozwB-3kkjA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 ILE A 128
PHE A 151
ALA A   6
ASN A 139
 FAD  A 401 (-4.0A)
None
None
None
 1.03A 3pgyA-3kkjA:
undetectable
3pgyB-3kkjA:
undetectable		 3pgyA-3kkjA:
22.07
3pgyB-3kkjA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 PHE A  31
CYH A 126
HIS A 148
 None
 1.29A 3u9fL-3kkjA:
undetectable		 3u9fL-3kkjA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 PHE A  31
CYH A 126
HIS A 148
 None
 1.24A 3u9fS-3kkjA:
undetectable		 3u9fS-3kkjA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 ALA A  13
ILE A  12
ARG A  40
GLY A 311
 FAD  A 401 (-3.1A)
None
FAD  A 401 (-3.6A)
None
 0.99A 3v4tH-3kkjA:
undetectable		 3v4tH-3kkjA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_C_ACTC506_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 ARG A 280
TRP A 276
HIS A 232
GLY A  54
 FAD  A 401 (-3.5A)
FAD  A 401 (-3.8A)
FAD  A 401 (-3.9A)
FAD  A 401 (-3.7A)
 1.31A 4e7cC-3kkjA:
undetectable		 4e7cC-3kkjA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 PHE A  31
ASP A  32
PRO A 121
ILE A 156
 None
FAD  A 401 (-2.9A)
None
None
 0.79A 4pcuA-3kkjA:
2.8		 4pcuA-3kkjA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 PHE A  65
VAL A 309
MET A 116
ILE A 112
 None
FAD  A 401 (-3.9A)
None
None
 1.22A 5iwuA-3kkjA:
undetectable		 5iwuA-3kkjA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_0
(REGULATORY PROTEIN
TETR)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 ALA A 312
GLY A 316
SER A 315
GLU A 318
TYR A 298
 FAD  A 401 (-3.6A)
None
None
None
None
 1.46A 5vlmF-3kkjA:
undetectable		 5vlmF-3kkjA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 ILE A 297
ALA A 170
ALA A 169
LEU A 173
ILE A   8
 None
None
None
None
FAD  A 401 (-4.8A)
 0.99A 6a5yD-3kkjA:
undetectable		 6a5yD-3kkjA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_B_EY4B500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 GLN A 248
VAL A 249
ALA A 233
THR A 234
 None
 0.94A 6cduB-3kkjA:
undetectable
6cduC-3kkjA:
undetectable		 6cduB-3kkjA:
22.16
6cduC-3kkjA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 LYS A 219
GLN A  56
GLY A  11
ILE A 112
 None
None
FAD  A 401 (-2.9A)
None
 1.39A 6debB-3kkjA:
undetectable		 6debB-3kkjA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 TYR A  57
LYS A 219
GLN A  56
GLY A 311
 FAD  A 401 (-4.4A)
None
None
None
 1.46A 6debB-3kkjA:
undetectable		 6debB-3kkjA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 GLY A   9
THR A  10
SER A 125
SER A  34
 FAD  A 401 (-3.6A)
None
None
FAD  A 401 (-3.4A)
 1.08A 6jmjA-3kkjA:
2.6		 6jmjA-3kkjA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3kkj AMINE OXIDASE,
FLAVIN-CONTAINING
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 GLY A   9
THR A  10
SER A 125
SER A  34
 FAD  A 401 (-3.6A)
None
None
FAD  A 401 (-3.4A)
 1.08A 6jogA-3kkjA:
2.7		 6jogA-3kkjA:
20.24