SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kkl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		5 / 11 ALA A 110
LEU A 142
LEU A 111
HIS A 108
LEU A 179
 None
 1.17A 1h9zA-3kklA:
undetectable		 1h9zA-3kklA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA888_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		4 / 6 PRO A   3
LYS A   4
ALA A   6
GLU A  39
 None
 1.35A 1qhyA-3kklA:
undetectable		 1qhyA-3kklA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		4 / 7 PHE A  38
LEU A 235
VAL A 133
GLY A 132
 None
 0.91A 1t88A-3kklA:
undetectable		 1t88A-3kklA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		4 / 4 SER A   9
ILE A   8
VAL A 101
THR A 211
 None
 1.18A 1u70A-3kklA:
undetectable		 1u70A-3kklA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 231
ILE A 229
SER A 226
ILE A 134
PHE A  38
 None
 1.16A 1ve3B-3kklA:
3.6		 1ve3B-3kklA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		5 / 12 THR A 227
ILE A  31
ALA A 136
ILE A 137
ALA A   6
 None
 1.33A 1vq1A-3kklA:
2.5		 1vq1A-3kklA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 156
GLY A 159
ALA A 196
ILE A 210
PRO A 141
ILE A 157
 None
 1.28A 2ienA-3kklA:
undetectable		 2ienA-3kklA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		3 / 3 SER A 223
HIS A 108
ASP A 176
 None
 0.85A 2oxtA-3kklA:
2.6		 2oxtA-3kklA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 156
GLY A 159
ALA A 196
ILE A 210
PRO A 141
ILE A 157
 None
 1.48A 2qakA-3kklA:
undetectable		 2qakA-3kklA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 156
GLY A 159
ALA A 196
ILE A 210
PRO A 141
ILE A 157
 None
 1.35A 2rkfB-3kklA:
undetectable		 2rkfB-3kklA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 156
GLY A 159
ALA A 196
ILE A 210
PRO A 141
ILE A 157
 None
 1.40A 2rkgA-3kklA:
undetectable		 2rkgA-3kklA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 156
GLY A 159
ALA A 196
ILE A 210
PRO A 141
ILE A 157
 None
 1.37A 3bvbA-3kklA:
undetectable		 3bvbA-3kklA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 156
GLY A 159
ALA A 196
ILE A 210
PRO A 141
ILE A 157
 None
 1.40A 3bvbB-3kklA:
undetectable		 3bvbB-3kklA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 156
GLY A 159
ALA A 196
ILE A 210
PRO A 141
ILE A 157
 None
 1.31A 3jw2A-3kklA:
undetectable		 3jw2A-3kklA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 156
GLY A 159
ALA A 196
ILE A 210
PRO A 141
ILE A 157
 None
 1.35A 3k4vA-3kklA:
undetectable		 3k4vA-3kklA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 156
GLY A 159
ALA A 196
ILE A 210
PRO A 141
ILE A 157
 None
 1.28A 3lzuB-3kklA:
undetectable		 3lzuB-3kklA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 156
GLY A 159
ALA A 196
ILE A 210
PRO A 141
ILE A 157
 None
 1.37A 3s54A-3kklA:
undetectable		 3s54A-3kklA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 156
GLY A 159
ALA A 196
ILE A 210
PRO A 141
ILE A 157
 None
 1.34A 3s54B-3kklA:
undetectable		 3s54B-3kklA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 156
GLY A 159
ALA A 196
ILE A 210
PRO A 141
ILE A 157
 None
 1.35A 3tkwB-3kklA:
undetectable		 3tkwB-3kklA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 156
GLY A 159
ALA A 196
VAL A 190
ILE A 210
PRO A 141
 None
 1.37A 3tkwB-3kklA:
undetectable		 3tkwB-3kklA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 156
GLY A 159
ALA A 196
ILE A 210
PRO A 141
ILE A 157
 None
 1.25A 3tl9B-3kklA:
undetectable		 3tl9B-3kklA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 156
GLY A 159
ALA A 196
ILE A 210
PRO A 141
ILE A 157
 None
 1.37A 5e5jB-3kklA:
undetectable		 5e5jB-3kklA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		4 / 7 ASP A 113
PHE A 112
GLY A  15
GLY A  25
 None
 0.87A 5n9xA-3kklA:
3.0		 5n9xA-3kklA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_2
(PROTEASE)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 156
GLY A 159
ALA A 196
ILE A 210
PRO A 141
ILE A 157
 None
 1.36A 5t8hB-3kklA:
undetectable		 5t8hB-3kklA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 165
PRO A 201
ILE A 202
SER A 223
 None
 1.06A 5vkqA-3kklA:
undetectable
5vkqD-3kklA:
undetectable		 5vkqA-3kklA:
8.37
5vkqD-3kklA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		4 / 7 SER A 223
PHE A 165
PRO A 201
ILE A 202
 None
 1.04A 5vkqA-3kklA:
undetectable
5vkqB-3kklA:
undetectable		 5vkqA-3kklA:
8.37
5vkqB-3kklA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3kkl PROBABLE CHAPERONE
PROTEIN HSP33
(Saccharomyces
cerevisiae) 		4 / 7 SER A 223
PHE A 165
PRO A 201
ILE A 202
 None
 1.05A 5vkqC-3kklA:
undetectable
5vkqD-3kklA:
undetectable		 5vkqC-3kklA:
8.37
5vkqD-3kklA:
8.37