SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kl2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		4 / 6 PHE A 154
LEU A 173
VAL A 196
VAL A 168
 None
 1.18A 1dz4B-3kl2A:
undetectable		 1dz4B-3kl2A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_B_STIB202_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		4 / 7 VAL A  46
ILE A 162
ARG A 149
LEU A 173
 None
 1.00A 1iepB-3kl2A:
undetectable		 1iepB-3kl2A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		4 / 5 PHE A 154
LEU A 173
VAL A 196
VAL A 168
 None
 1.14A 1t88B-3kl2A:
undetectable		 1t88B-3kl2A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		4 / 6 PHE A 154
LEU A 173
VAL A 196
VAL A 168
 None
 1.07A 2feuA-3kl2A:
undetectable		 2feuA-3kl2A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M56_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		4 / 5 PHE A 154
LEU A 173
VAL A 196
VAL A 168
 None
 1.16A 2m56A-3kl2A:
undetectable		 2m56A-3kl2A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS9_C_NILC600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		5 / 9 LEU A 136
TYR A  50
VAL A 133
VAL A  68
PHE A 176
 None
 1.15A 3cs9C-3kl2A:
undetectable		 3cs9C-3kl2A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		4 / 6 PHE A 154
LEU A 173
VAL A 196
VAL A 168
 None
 1.09A 3fwgA-3kl2A:
undetectable		 3fwgA-3kl2A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		5 / 12 CYH A 181
THR A 185
THR A 188
ILE A  97
LEU A 173
 None
 0.65A 3gwxA-3kl2A:
undetectable		 3gwxA-3kl2A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		4 / 6 PHE A 154
LEU A 173
VAL A 196
VAL A 168
 None
 1.10A 3wrhE-3kl2A:
undetectable		 3wrhE-3kl2A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		4 / 6 PHE A 154
LEU A 173
VAL A 196
VAL A 168
 None
 1.09A 3wrjE-3kl2A:
undetectable		 3wrjE-3kl2A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		4 / 6 PHE A 154
LEU A 173
VAL A 196
VAL A 168
 None
 1.04A 4ek1A-3kl2A:
undetectable		 4ek1A-3kl2A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		4 / 6 PHE A 154
LEU A 173
VAL A 196
VAL A 168
 None
 1.08A 4g3rA-3kl2A:
undetectable		 4g3rA-3kl2A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		4 / 6 PHE A 154
LEU A 173
VAL A 196
VAL A 168
 None
 1.10A 4g3rB-3kl2A:
undetectable		 4g3rB-3kl2A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		4 / 6 PHE A 154
LEU A 173
VAL A 196
VAL A 168
 None
 1.15A 4kkyX-3kl2A:
undetectable		 4kkyX-3kl2A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L49_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		4 / 5 PHE A 154
LEU A 173
VAL A 196
VAL A 168
 None
 1.12A 4l49A-3kl2A:
undetectable		 4l49A-3kl2A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		4 / 6 PHE A 154
LEU A 173
VAL A 196
VAL A 168
 None
 1.06A 4l4cA-3kl2A:
undetectable		 4l4cA-3kl2A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_A_AERA601_1
(CYP17A1 PROTEIN)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		5 / 9 ALA A 214
TYR A  50
ILE A  48
ALA A 205
THR A 206
 None
 1.23A 4r1zA-3kl2A:
undetectable		 4r1zA-3kl2A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		4 / 6 HIS A 211
VAL A  68
LEU A 177
THR A 178
 None
 0.94A 5ogjA-3kl2A:
undetectable		 5ogjA-3kl2A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		4 / 6 HIS A 211
VAL A  68
LEU A 177
THR A 178
 None
 0.94A 5ogjB-3kl2A:
undetectable		 5ogjB-3kl2A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		4 / 5 HIS A 211
VAL A  68
LEU A 177
THR A 178
 None
 0.94A 5ohhA-3kl2A:
undetectable		 5ohhA-3kl2A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		4 / 6 HIS A 211
VAL A  68
LEU A 177
THR A 178
 None
 0.95A 5ohhB-3kl2A:
undetectable		 5ohhB-3kl2A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3kl2 PUTATIVE
ISOCHORISMATASE
(Streptomyces
avermitilis) 		4 / 7 PHE A 154
LEU A 173
VAL A 196
VAL A 168
 None
 1.04A 5wk9A-3kl2A:
undetectable		 5wk9A-3kl2A:
21.28