SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kl7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 5 HIS A  84
HIS A 146
HIS A 215
ASP A  83
 ZN  A 303 (-3.4A)
ZN  A 302 (-3.3A)
ZN  A 303 (-3.3A)
ZN  A 303 (-2.7A)
 0.98A 1e9yB-3kl7A:
undetectable		 1e9yB-3kl7A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 7 ILE A 101
MET A 128
THR A 157
LEU A 156
 None
None
GOL  A 306 (-4.7A)
None
 0.94A 1v55A-3kl7A:
undetectable
1v55J-3kl7A:
undetectable		 1v55A-3kl7A:
16.47
1v55J-3kl7A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_2
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 9 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.90A 2idwB-3kl7A:
undetectable		 2idwB-3kl7A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		6 / 12 LEU A 156
GLY A 153
ALA A 132
ASP A 120
ILE A  77
ILE A 130
 None
 1.11A 2ienA-3kl7A:
undetectable		 2ienA-3kl7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 9 GLU A  94
ILE A  90
ILE A  75
LYS A 112
ILE A 100
 None
 1.42A 2j9dA-3kl7A:
0.2
2j9dB-3kl7A:
0.0
2j9dC-3kl7A:
0.0		 2j9dA-3kl7A:
19.47
2j9dB-3kl7A:
19.47
2j9dC-3kl7A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 9 ILE A  75
LYS A 112
ILE A 100
GLU A  94
ILE A  90
 None
 1.34A 2j9dA-3kl7A:
0.2
2j9dB-3kl7A:
0.0
2j9dC-3kl7A:
0.0		 2j9dA-3kl7A:
19.47
2j9dB-3kl7A:
19.47
2j9dC-3kl7A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 9 LYS A 112
ILE A 100
GLU A  94
ILE A  90
ILE A  75
 None
 1.35A 2j9dA-3kl7A:
0.2
2j9dB-3kl7A:
0.0
2j9dC-3kl7A:
0.0		 2j9dA-3kl7A:
19.47
2j9dB-3kl7A:
19.47
2j9dC-3kl7A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 10 GLU A  94
ILE A  90
ILE A  75
LYS A 112
ILE A 100
 None
 1.35A 2j9dD-3kl7A:
undetectable
2j9dE-3kl7A:
undetectable
2j9dF-3kl7A:
undetectable		 2j9dD-3kl7A:
19.47
2j9dE-3kl7A:
19.47
2j9dF-3kl7A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 10 ILE A  75
LYS A 112
ILE A 100
GLU A  94
ILE A  90
 None
 1.34A 2j9dD-3kl7A:
undetectable
2j9dE-3kl7A:
undetectable
2j9dF-3kl7A:
undetectable		 2j9dD-3kl7A:
19.47
2j9dE-3kl7A:
19.47
2j9dF-3kl7A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 10 LYS A 112
ILE A 100
GLU A  94
ILE A  90
ILE A  75
 None
 1.41A 2j9dD-3kl7A:
undetectable
2j9dE-3kl7A:
undetectable
2j9dF-3kl7A:
undetectable		 2j9dD-3kl7A:
19.47
2j9dE-3kl7A:
19.47
2j9dF-3kl7A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 9 GLU A  94
ILE A  90
ILE A  75
LYS A 112
ILE A 100
 None
 1.37A 2j9dG-3kl7A:
0.3
2j9dH-3kl7A:
0.0
2j9dI-3kl7A:
0.2		 2j9dG-3kl7A:
19.47
2j9dH-3kl7A:
19.47
2j9dI-3kl7A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 9 ILE A  75
LYS A 112
ILE A 100
GLU A  94
ILE A  90
 None
 1.36A 2j9dG-3kl7A:
0.3
2j9dH-3kl7A:
0.0
2j9dI-3kl7A:
0.2		 2j9dG-3kl7A:
19.47
2j9dH-3kl7A:
19.47
2j9dI-3kl7A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 9 LYS A 112
ILE A 100
GLU A  94
ILE A  90
ILE A  75
 None
 1.32A 2j9dG-3kl7A:
0.3
2j9dH-3kl7A:
0.0
2j9dI-3kl7A:
0.2		 2j9dG-3kl7A:
19.47
2j9dH-3kl7A:
19.47
2j9dI-3kl7A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.80A 2nmyB-3kl7A:
undetectable		 2nmyB-3kl7A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.83A 2nmzA-3kl7A:
undetectable		 2nmzA-3kl7A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.80A 2nmzB-3kl7A:
undetectable		 2nmzB-3kl7A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		3 / 3 SER A 126
ASP A  73
ASP A  51
 None
 0.71A 2plwA-3kl7A:
undetectable		 2plwA-3kl7A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0J_B_BEZB500_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 11 ASP A  83
HIS A  84
HIS A 146
ASP A 168
HIS A 215
 ZN  A 303 (-2.7A)
ZN  A 303 (-3.4A)
ZN  A 302 (-3.3A)
ZN  A 303 ( 2.5A)
ZN  A 303 (-3.3A)
 0.64A 2q0jB-3kl7A:
9.8		 2q0jB-3kl7A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 8 ILE A 101
MET A 128
THR A 157
LEU A 156
 None
None
GOL  A 306 (-4.7A)
None
 0.90A 3abkA-3kl7A:
undetectable
3abkJ-3kl7A:
undetectable		 3abkA-3kl7A:
16.47
3abkJ-3kl7A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 7 ILE A 101
MET A 128
THR A 157
LEU A 156
 None
None
GOL  A 306 (-4.7A)
None
 0.91A 3ag3A-3kl7A:
undetectable
3ag3J-3kl7A:
undetectable		 3ag3A-3kl7A:
16.47
3ag3J-3kl7A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.89A 3bvbB-3kl7A:
undetectable		 3bvbB-3kl7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 8 HIS A  84
HIS A  79
ASP A  83
HIS A  81
GLY A  82
 ZN  A 303 (-3.4A)
ZN  A 302 (-3.5A)
ZN  A 303 (-2.7A)
ZN  A 302 (-3.4A)
None
 1.35A 3c0zB-3kl7A:
undetectable		 3c0zB-3kl7A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.89A 3cywB-3kl7A:
undetectable		 3cywB-3kl7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_2
(HIV-1 PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.88A 3d1zB-3kl7A:
undetectable		 3d1zB-3kl7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_1
(HIV-1 PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.94A 3d20A-3kl7A:
undetectable		 3d20A-3kl7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_2
(HIV-1 PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.87A 3d20B-3kl7A:
undetectable		 3d20B-3kl7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 11 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.97A 3ektD-3kl7A:
undetectable		 3ektD-3kl7A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 10 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.82A 3ekvA-3kl7A:
undetectable		 3ekvA-3kl7A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 8 ILE A  41
ALA A  64
THR A  68
ALA A  92
 None
 0.95A 3hrdA-3kl7A:
undetectable
3hrdB-3kl7A:
undetectable		 3hrdA-3kl7A:
20.09
3hrdB-3kl7A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.86A 3k4vB-3kl7A:
undetectable		 3k4vB-3kl7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.93A 3lzsB-3kl7A:
undetectable		 3lzsB-3kl7A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.92A 3lzuA-3kl7A:
undetectable		 3lzuA-3kl7A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.86A 3ndtB-3kl7A:
undetectable		 3ndtB-3kl7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_1
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.78A 3ndtC-3kl7A:
undetectable		 3ndtC-3kl7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.86A 3ndtD-3kl7A:
undetectable		 3ndtD-3kl7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.89A 3nduA-3kl7A:
undetectable		 3nduA-3kl7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_1
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.82A 3nduC-3kl7A:
undetectable		 3nduC-3kl7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_2
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 11 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.84A 3nu3B-3kl7A:
undetectable		 3nu3B-3kl7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 9 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.83A 3nu4B-3kl7A:
undetectable		 3nu4B-3kl7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 10 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.86A 3nu6B-3kl7A:
undetectable		 3nu6B-3kl7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_2
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 9 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.85A 3nujB-3kl7A:
undetectable		 3nujB-3kl7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_2
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 9 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.84A 3nuoB-3kl7A:
undetectable		 3nuoB-3kl7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_2
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.84A 3pwmB-3kl7A:
undetectable		 3pwmB-3kl7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.84A 3pwrB-3kl7A:
undetectable		 3pwrB-3kl7A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 8 ILE A 130
LEU A 116
LYS A 112
GLY A 113
 None
 0.93A 3selX-3kl7A:
undetectable		 3selX-3kl7A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 7 ASN A 137
ASP A  83
HIS A  84
HIS A 215
 None
ZN  A 303 (-2.7A)
ZN  A 303 (-3.4A)
ZN  A 303 (-3.3A)
 0.78A 3t01A-3kl7A:
undetectable		 3t01A-3kl7A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.82A 3tkgA-3kl7A:
undetectable		 3tkgA-3kl7A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.90A 3tkgB-3kl7A:
undetectable		 3tkgB-3kl7A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
ALA A 132
ASP A 120
ILE A  77
ILE A 130
 None
 0.95A 3tkgD-3kl7A:
undetectable		 3tkgD-3kl7A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.84A 3tkgD-3kl7A:
undetectable		 3tkgD-3kl7A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.85A 3tl9A-3kl7A:
undetectable		 3tl9A-3kl7A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 6 ILE A 101
MET A 128
THR A 157
LEU A 156
 None
None
GOL  A 306 (-4.7A)
None
 0.94A 3wg7N-3kl7A:
undetectable
3wg7W-3kl7A:
undetectable		 3wg7N-3kl7A:
16.47
3wg7W-3kl7A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 10 HIS A  84
HIS A  79
ASP A  83
HIS A  81
GLY A  82
 ZN  A 303 (-3.4A)
ZN  A 302 (-3.5A)
ZN  A 303 (-2.7A)
ZN  A 302 (-3.4A)
None
 1.38A 4bz6A-3kl7A:
undetectable		 4bz6A-3kl7A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 HIS A  84
HIS A  79
ASP A  83
HIS A  81
GLY A  82
 ZN  A 303 (-3.4A)
ZN  A 302 (-3.5A)
ZN  A 303 (-2.7A)
ZN  A 302 (-3.4A)
None
 1.39A 4bz6A-3kl7A:
undetectable
4bz6B-3kl7A:
undetectable		 4bz6A-3kl7A:
19.08
4bz6B-3kl7A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 10 HIS A  84
HIS A  79
ASP A  83
HIS A  81
GLY A  82
 ZN  A 303 (-3.4A)
ZN  A 302 (-3.5A)
ZN  A 303 (-2.7A)
ZN  A 302 (-3.4A)
None
 1.38A 4bz6D-3kl7A:
undetectable		 4bz6D-3kl7A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1D_B_X8ZB350_1
(BETA-LACTAMASE CLASS
B VIM-2)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 10 HIS A  79
HIS A  81
ASP A  83
HIS A 146
HIS A 215
 ZN  A 302 (-3.5A)
ZN  A 302 (-3.4A)
ZN  A 303 (-2.7A)
ZN  A 302 (-3.3A)
ZN  A 303 (-3.3A)
 0.92A 4c1dB-3kl7A:
2.8		 4c1dB-3kl7A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 11 HIS A  79
HIS A  81
ASP A  83
HIS A 146
HIS A 215
 ZN  A 302 (-3.5A)
ZN  A 302 (-3.4A)
ZN  A 303 (-2.7A)
ZN  A 302 (-3.3A)
ZN  A 303 (-3.3A)
 0.93A 4c1fA-3kl7A:
3.7
4c1fB-3kl7A:
2.5		 4c1fA-3kl7A:
24.22
4c1fB-3kl7A:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1H_A_X8ZA305_1
(BETA-LACTAMASE 2)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 9 HIS A  79
HIS A  81
ASP A  83
HIS A 146
HIS A 215
 ZN  A 302 (-3.5A)
ZN  A 302 (-3.4A)
ZN  A 303 (-2.7A)
ZN  A 302 (-3.3A)
ZN  A 303 (-3.3A)
 0.92A 4c1hA-3kl7A:
3.2		 4c1hA-3kl7A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 10 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.89A 4dqfB-3kl7A:
undetectable		 4dqfB-3kl7A:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EXS_B_X8ZB301_1
(BETA-LACTAMASE NDM-1)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 8 HIS A  81
ASP A  83
HIS A 146
HIS A 215
 ZN  A 302 (-3.4A)
ZN  A 303 (-2.7A)
ZN  A 302 (-3.3A)
ZN  A 303 (-3.3A)
 0.87A 4exsB-3kl7A:
5.7		 4exsB-3kl7A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 7 ILE A 130
LEU A 116
LYS A 112
GLY A 113
 None
 0.92A 4hajA-3kl7A:
undetectable		 4hajA-3kl7A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 7 ILE A 130
LEU A 116
LYS A 112
GLY A 113
 None
 0.98A 4hc3A-3kl7A:
undetectable		 4hc3A-3kl7A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_2
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 10 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.90A 4ll3B-3kl7A:
undetectable		 4ll3B-3kl7A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 11 HIS A  84
HIS A  79
ASP A  83
HIS A  81
GLY A  82
 ZN  A 303 (-3.4A)
ZN  A 302 (-3.5A)
ZN  A 303 (-2.7A)
ZN  A 302 (-3.4A)
None
 1.37A 4lxzB-3kl7A:
undetectable		 4lxzB-3kl7A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_2
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 9 LEU A 156
GLY A 153
ALA A 132
ASP A 120
ILE A  77
 None
 1.11A 4njtD-3kl7A:
undetectable		 4njtD-3kl7A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P68_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 11 ILE A  38
PHE A  28
ARG A 236
ILE A 183
THR A  49
 None
 1.37A 4p68A-3kl7A:
undetectable		 4p68A-3kl7A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 6 GLU A 170
GLN A 190
THR A  78
HIS A  84
 None
None
None
ZN  A 303 (-3.4A)
 1.33A 4pfjB-3kl7A:
undetectable		 4pfjB-3kl7A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 11 HIS A  84
HIS A  79
ASP A  83
HIS A  81
GLY A  82
 ZN  A 303 (-3.4A)
ZN  A 302 (-3.5A)
ZN  A 303 (-2.7A)
ZN  A 302 (-3.4A)
None
 1.37A 4qa0B-3kl7A:
undetectable		 4qa0B-3kl7A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_2
(HIV-1 PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 9 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.83A 4rvjB-3kl7A:
undetectable		 4rvjB-3kl7A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_2
(HIV-1 PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 9 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.83A 4rvjD-3kl7A:
undetectable		 4rvjD-3kl7A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_A_WJZA304_0
(BETA-LACTAMASE NDM-1)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 8 HIS A  81
ASP A  83
HIS A 146
HIS A 215
 ZN  A 302 (-3.4A)
ZN  A 303 (-2.7A)
ZN  A 302 (-3.3A)
ZN  A 303 (-3.3A)
 0.87A 5a5zA-3kl7A:
8.3		 5a5zA-3kl7A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		6 / 11 HIS A  79
HIS A  81
ASP A  83
HIS A  84
HIS A 146
HIS A 215
 ZN  A 302 (-3.5A)
ZN  A 302 (-3.4A)
ZN  A 303 (-2.7A)
ZN  A 303 (-3.4A)
ZN  A 302 (-3.3A)
ZN  A 303 (-3.3A)
 0.34A 5ayaA-3kl7A:
9.9		 5ayaA-3kl7A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		6 / 11 HIS A  79
HIS A  81
ASP A  83
HIS A  84
HIS A 146
THR A 193
 ZN  A 302 (-3.5A)
ZN  A 302 (-3.4A)
ZN  A 303 (-2.7A)
ZN  A 303 (-3.4A)
ZN  A 302 (-3.3A)
None
 0.94A 5ayaA-3kl7A:
9.9		 5ayaA-3kl7A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYA_A_X8ZA307_1
(METALLO-BETA-LACTAMA
SE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 11 HIS A  79
HIS A  81
HIS A  84
THR A 193
HIS A  43
 ZN  A 302 (-3.5A)
ZN  A 302 (-3.4A)
ZN  A 303 (-3.4A)
None
UNL  A 301 ( 4.0A)
 1.07A 5ayaA-3kl7A:
9.9		 5ayaA-3kl7A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 7 ILE A 101
MET A 128
THR A 157
LEU A 156
 None
None
GOL  A 306 (-4.7A)
None
 0.89A 5b1aA-3kl7A:
undetectable
5b1aJ-3kl7A:
undetectable		 5b1aA-3kl7A:
16.47
5b1aJ-3kl7A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 7 ILE A 101
MET A 128
THR A 157
LEU A 156
 None
None
GOL  A 306 (-4.7A)
None
 0.89A 5b3sA-3kl7A:
undetectable
5b3sJ-3kl7A:
undetectable		 5b3sA-3kl7A:
16.47
5b3sJ-3kl7A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 7 ILE A 101
MET A 128
THR A 157
LEU A 156
 None
None
GOL  A 306 (-4.7A)
None
 0.90A 5b3sN-3kl7A:
undetectable
5b3sW-3kl7A:
undetectable		 5b3sN-3kl7A:
16.47
5b3sW-3kl7A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 4 LEU A 228
ILE A 233
PRO A 213
LEU A 186
 None
 1.15A 5eb3A-3kl7A:
undetectable		 5eb3A-3kl7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_2
(PROTEASE PR5-SQV)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 11 LEU A 156
ALA A 132
ASP A 120
ILE A  77
ILE A 130
 None
 0.84A 5kr2B-3kl7A:
undetectable		 5kr2B-3kl7A:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		3 / 3 THR A  78
PRO A 147
ARG A 148
 None
 0.84A 5nd7B-3kl7A:
undetectable		 5nd7B-3kl7A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 8 ASP A 168
HIS A  84
HIS A 215
HIS A 146
 ZN  A 303 ( 2.5A)
ZN  A 303 (-3.4A)
ZN  A 303 (-3.3A)
ZN  A 302 (-3.3A)
 0.91A 5nekD-3kl7A:
undetectable		 5nekD-3kl7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 10 HIS A  79
HIS A  81
HIS A  84
HIS A 146
ASP A 168
 ZN  A 302 (-3.5A)
ZN  A 302 (-3.4A)
ZN  A 303 (-3.4A)
ZN  A 302 (-3.3A)
ZN  A 303 ( 2.5A)
 0.36A 5nzwA-3kl7A:
12.0		 5nzwA-3kl7A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZW_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 10 HIS A  84
HIS A 215
HIS A  79
ASP A 168
HIS A 146
 ZN  A 303 (-3.4A)
ZN  A 303 (-3.3A)
ZN  A 302 (-3.5A)
ZN  A 303 ( 2.5A)
ZN  A 302 (-3.3A)
 1.00A 5nzwA-3kl7A:
12.0		 5nzwA-3kl7A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODC_A_ACTA703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 4 GLN A 190
GLN A 198
PRO A 187
ALA A 199
 None
 1.40A 5odcA-3kl7A:
2.2
5odcG-3kl7A:
2.4		 5odcA-3kl7A:
16.64
5odcG-3kl7A:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODC_G_ACTG704_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 5 PRO A 187
ALA A 199
GLN A 190
GLN A 198
 None
 1.40A 5odcA-3kl7A:
2.2
5odcG-3kl7A:
2.4		 5odcA-3kl7A:
16.64
5odcG-3kl7A:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 7 ILE A 101
MET A 128
THR A 157
LEU A 156
 None
None
GOL  A 306 (-4.7A)
None
 0.89A 5xdxA-3kl7A:
undetectable
5xdxJ-3kl7A:
undetectable		 5xdxA-3kl7A:
16.47
5xdxJ-3kl7A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 6 ILE A 101
MET A 128
THR A 157
LEU A 156
 None
None
GOL  A 306 (-4.7A)
None
 0.92A 5z86N-3kl7A:
undetectable
5z86W-3kl7A:
undetectable		 5z86N-3kl7A:
16.47
5z86W-3kl7A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 6 ILE A 101
MET A 128
THR A 157
LEU A 156
 None
None
GOL  A 306 (-4.7A)
None
 0.92A 5zcoN-3kl7A:
undetectable
5zcoW-3kl7A:
undetectable		 5zcoN-3kl7A:
16.47
5zcoW-3kl7A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 7 ILE A 101
MET A 128
THR A 157
LEU A 156
 None
None
GOL  A 306 (-4.7A)
None
 0.88A 5zcpA-3kl7A:
undetectable
5zcpJ-3kl7A:
undetectable		 5zcpA-3kl7A:
16.47
5zcpJ-3kl7A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 8 ILE A 101
MET A 128
THR A 157
LEU A 156
 None
None
GOL  A 306 (-4.7A)
None
 0.91A 5zcpN-3kl7A:
undetectable
5zcpW-3kl7A:
undetectable		 5zcpN-3kl7A:
16.47
5zcpW-3kl7A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 7 ILE A 101
MET A 128
THR A 157
LEU A 156
 None
None
GOL  A 306 (-4.7A)
None
 0.88A 5zcqA-3kl7A:
undetectable
5zcqJ-3kl7A:
undetectable		 5zcqA-3kl7A:
16.47
5zcqJ-3kl7A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJ8_A_9DCA303_0
(METALLO-BETA-LACTAMA
SE TYPE 2)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 8 HIS A  81
ASP A  83
HIS A  79
HIS A 215
 ZN  A 302 (-3.4A)
ZN  A 303 (-2.7A)
ZN  A 302 (-3.5A)
ZN  A 303 (-3.3A)
 1.02A 5zj8A-3kl7A:
5.2		 5zj8A-3kl7A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJ8_A_9DCA303_0
(METALLO-BETA-LACTAMA
SE TYPE 2)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		4 / 8 HIS A  81
ASP A  83
HIS A 146
HIS A 215
 ZN  A 302 (-3.4A)
ZN  A 303 (-2.7A)
ZN  A 302 (-3.3A)
ZN  A 303 (-3.3A)
 0.93A 5zj8A-3kl7A:
5.2		 5zj8A-3kl7A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.92A 6dgxA-3kl7A:
undetectable		 6dgxA-3kl7A:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_0
(PROTEASE)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 12 LEU A 156
GLY A 153
ASP A 120
ILE A  77
ILE A 130
 None
 0.90A 6dh3A-3kl7A:
undetectable		 6dh3A-3kl7A:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCO_A_FY5A1003_0
(ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
2)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 11 MET A 175
THR A 169
ILE A 221
VAL A 188
MET A 194
 None
None
None
GOL  A 308 (-4.2A)
None
 1.26A 6hcoA-3kl7A:
undetectable
6hcoB-3kl7A:
undetectable		 6hcoA-3kl7A:
16.36
6hcoB-3kl7A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCO_A_FY5A1003_0
(ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
2)		 3kl7 PUTATIVE
METAL-DEPENDENT
HYDROLASE
(Parabacteroides
distasonis) 		5 / 11 THR A 169
VAL A 188
MET A 194
ILE A 155
MET A 175
 None
GOL  A 308 (-4.2A)
None
GOL  A 305 (-4.9A)
None
 1.19A 6hcoA-3kl7A:
undetectable
6hcoB-3kl7A:
undetectable		 6hcoA-3kl7A:
16.36
6hcoB-3kl7A:
16.36