SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kln'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DG5_A_TOPA201_1
(DIHYDROFOLATE
REDUCTASE)		 3kln TRANSCRIPTIONAL
REGULATOR, LUXR
FAMILY
(Vibrio
cholerae) 		5 / 11 ILE A  87
ALA A 106
ILE A 125
LEU A  26
ILE A  88
 None
 1.17A 1dg5A-3klnA:
undetectable		 1dg5A-3klnA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3kln TRANSCRIPTIONAL
REGULATOR, LUXR
FAMILY
(Vibrio
cholerae) 		5 / 11 GLN A  92
VAL A  86
ALA A 106
ILE A 125
ARG A 134
 None
 1.18A 3n23A-3klnA:
undetectable		 3n23A-3klnA:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3kln TRANSCRIPTIONAL
REGULATOR, LUXR
FAMILY
(Vibrio
cholerae) 		4 / 5 LYS A  23
LEU A  26
GLU A  27
LEU A  32
 None
 1.29A 4k4yA-3klnA:
undetectable		 4k4yA-3klnA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3kln TRANSCRIPTIONAL
REGULATOR, LUXR
FAMILY
(Vibrio
cholerae) 		4 / 4 LYS A  23
LEU A  26
GLU A  27
LEU A  32
 None
 1.31A 4k4yE-3klnA:
undetectable		 4k4yE-3klnA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3kln TRANSCRIPTIONAL
REGULATOR, LUXR
FAMILY
(Vibrio
cholerae) 		4 / 5 LYS A  23
LEU A  26
GLU A  27
LEU A  32
 None
 1.32A 4k4yI-3klnA:
undetectable		 4k4yI-3klnA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 3kln TRANSCRIPTIONAL
REGULATOR, LUXR
FAMILY
(Vibrio
cholerae) 		4 / 7 ASN A 205
GLY A 173
ALA A 174
VAL A 190
 None
 0.84A 6dwnB-3klnA:
undetectable		 6dwnB-3klnA:
16.75