SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kls'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_B_GBMB801_1
(PROLINE--TRNA LIGASE)		 3kls EXOTOXIN 1
(Staphylococcus
aureus) 		5 / 9 ILE X 155
LEU X 165
ARG X 222
ILE X 224
GLY X 223
 None
 1.23A 5ifuB-3klsX:
undetectable		 5ifuB-3klsX:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3kls EXOTOXIN 1
(Staphylococcus
aureus) 		4 / 9 ILE X 169
PHE X 153
VAL X 138
ASN X 176
 None
 1.06A 5lg3I-3klsX:
undetectable		 5lg3I-3klsX:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_A_CCSA14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 3kls EXOTOXIN 1
(Staphylococcus
aureus) 		4 / 6 PHE X  85
ASN X  71
LEU X  86
GLY X 120
 None
 1.05A 5o4yA-3klsX:
undetectable		 5o4yA-3klsX:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3kls EXOTOXIN 1
(Staphylococcus
aureus) 		3 / 3 GLY X 187
THR X 227
ASN X 229
 None
 0.61A 5odiG-3klsX:
undetectable		 5odiG-3klsX:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 3kls EXOTOXIN 1
(Staphylococcus
aureus) 		3 / 3 LEU X 173
LEU X 203
ARG X 170
 None
 0.66A 6fgcA-3klsX:
undetectable		 6fgcA-3klsX:
20.05