SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3klu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 3klu UNCHARACTERIZED
PROTEIN YQBN
(Bacillus
subtilis) 		4 / 8 PHE A  81
TYR A  82
ILE A  85
PHE A 136
 None
 0.74A 1fslB-3kluA:
undetectable		 1fslB-3kluA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 3klu UNCHARACTERIZED
PROTEIN YQBN
(Bacillus
subtilis) 		4 / 7 PRO A 109
VAL A 110
GLU A  60
ARG A  80
 None
 1.04A 2v2gA-3kluA:
undetectable
2v2gB-3kluA:
undetectable		 2v2gA-3kluA:
22.71
2v2gB-3kluA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 3klu UNCHARACTERIZED
PROTEIN YQBN
(Bacillus
subtilis) 		4 / 7 PRO A 109
VAL A 110
GLU A  60
ARG A  80
 None
 1.05A 2v2gC-3kluA:
undetectable
2v2gD-3kluA:
undetectable		 2v2gC-3kluA:
22.71
2v2gD-3kluA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 3klu UNCHARACTERIZED
PROTEIN YQBN
(Bacillus
subtilis) 		4 / 8 PRO A 109
VAL A 110
GLU A  60
ARG A  80
 None
 1.00A 2v41C-3kluA:
undetectable
2v41D-3kluA:
undetectable		 2v41C-3kluA:
22.71
2v41D-3kluA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 3klu UNCHARACTERIZED
PROTEIN YQBN
(Bacillus
subtilis) 		4 / 7 PRO A 109
VAL A 110
GLU A  60
ARG A  80
 None
 1.02A 2v41E-3kluA:
undetectable
2v41F-3kluA:
undetectable		 2v41E-3kluA:
22.71
2v41F-3kluA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 3klu UNCHARACTERIZED
PROTEIN YQBN
(Bacillus
subtilis) 		4 / 8 PHE A  44
ALA A 130
PHE A  46
PHE A  95
 None
 0.93A 3t3sD-3kluA:
undetectable		 3t3sD-3kluA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_B_SFYB806_0
(SEPIAPTERIN
REDUCTASE)		 3klu UNCHARACTERIZED
PROTEIN YQBN
(Bacillus
subtilis) 		5 / 11 LEU A 127
TRP A 126
TYR A 123
PRO A 109
ALA A  86
 None
 1.22A 4hwkB-3kluA:
undetectable		 4hwkB-3kluA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_C_SFYC804_0
(SEPIAPTERIN
REDUCTASE)		 3klu UNCHARACTERIZED
PROTEIN YQBN
(Bacillus
subtilis) 		5 / 12 LEU A 127
TRP A 126
TYR A 123
PRO A 109
ALA A  86
 None
 1.21A 4hwkC-3kluA:
undetectable		 4hwkC-3kluA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_D_SFYD803_0
(SEPIAPTERIN
REDUCTASE)		 3klu UNCHARACTERIZED
PROTEIN YQBN
(Bacillus
subtilis) 		5 / 11 LEU A 127
TRP A 126
TYR A 123
PRO A 109
ALA A  86
 None
 1.27A 4hwkD-3kluA:
undetectable		 4hwkD-3kluA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 3klu UNCHARACTERIZED
PROTEIN YQBN
(Bacillus
subtilis) 		4 / 5 PRO A 109
VAL A  87
GLY A 120
VAL A 116
 None
 1.00A 6ak3B-3kluA:
undetectable		 6ak3B-3kluA:
20.00