SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kml'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LBD_A_9CRA424_1 (RETINOIC ACID RECEPTOR GAMMA)	3kml	COAT PROTEIN (Tobacco mosaic virus)	5 / 12	LEU A 34 ILE A 27 ARG A 24 PHE A 110 ALA A 80	None	1.32A	3lbdA-3kmlA: undetectable	3lbdA-3kmlA: 20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R82_A_ACTA205_0 (OXIDOREDUCTASE)	3kml	COAT PROTEIN (Tobacco mosaic virus)	4 / 5	SER A 50 GLY A 51 GLU A 47 PHE A 46	None	1.26A	4r82A-3kmlA: undetectable 4r82B-3kmlA: undetectable	4r82A-3kmlA: 19.49 4r82B-3kmlA: 19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_O_DVAO7_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	3kml	COAT PROTEIN (Tobacco mosaic virus)	3 / 3	TYR A 41 SER A 50 TRP A 79	None	1.04A	5n8jA-3kmlA: undetectable	5n8jA-3kmlA: 25.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_P_DVAP5_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	3kml	COAT PROTEIN (Tobacco mosaic virus)	3 / 3	TYR A 41 SER A 50 TRP A 79	None	1.03A	5n8jD-3kmlA: undetectable	5n8jD-3kmlA: 25.38

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3LBD_A_9CRA424_1","RETINOIC ACID RECEPTOR GAMMA","3kml","COAT PROTEIN","Tobacco mosaic virus",5,"LEU A  34;ILE A  27;ARG A  24;PHE A 110;ALA A  80","None","1.32A","3lbdA-3kmlA:undetectable","3lbdA-3kmlA:20.70"],["4R82_A_ACTA205_0","OXIDOREDUCTASE","3kml","COAT PROTEIN","Tobacco mosaic virus",4,"SER A  50;GLY A  51;GLU A  47;PHE A  46","None","1.26A","4r82A-3kmlA:undetectable;4r82B-3kmlA:undetectable","4r82A-3kmlA:19.49;4r82B-3kmlA:19.49"],["5N8J_O_DVAO7_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","3kml","COAT PROTEIN","Tobacco mosaic virus",3,"TYR A  41;SER A  50;TRP A  79","None","1.04A","5n8jA-3kmlA:undetectable","5n8jA-3kmlA:25.38"],["5N8J_P_DVAP5_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","3kml","COAT PROTEIN","Tobacco mosaic virus",3,"TYR A  41;SER A  50;TRP A  79","None","1.03A","5n8jD-3kmlA:undetectable","5n8jD-3kmlA:25.38"]]