SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kmv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 3kmv ALPHA-L-ARABINOFURAN
OSIDASE B
(Ruminiclostridiu
m
thermocellum) 		4 / 5 HIS A  25
SER A  59
LEU A  50
GLY A  67
 FMT  A 162 (-3.8A)
None
None
None
 1.10A 1a4lB-3kmvA:
undetectable		 1a4lB-3kmvA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_A_ADNA601_1
(METHIONYL-TRNA
SYNTHETASE)		 3kmv ALPHA-L-ARABINOFURAN
OSIDASE B
(Ruminiclostridiu
m
thermocellum) 		5 / 11 ALA A  89
ALA A  92
GLY A  67
GLY A  84
ASP A  83
 None
None
None
None
FMT  A 160 (-3.0A)
 1.12A 2x1lA-3kmvA:
undetectable		 2x1lA-3kmvA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_C_ADNC601_1
(METHIONYL-TRNA
SYNTHETASE)		 3kmv ALPHA-L-ARABINOFURAN
OSIDASE B
(Ruminiclostridiu
m
thermocellum) 		5 / 11 ALA A  89
ALA A  92
GLY A  67
GLY A  84
ASP A  83
 None
None
None
None
FMT  A 160 (-3.0A)
 1.12A 2x1lC-3kmvA:
undetectable		 2x1lC-3kmvA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3kmv ALPHA-L-ARABINOFURAN
OSIDASE B
(Ruminiclostridiu
m
thermocellum) 		4 / 6 ARG A  31
ILE A  32
ILE A  96
LEU A 100
 None
 0.90A 2xkwB-3kmvA:
undetectable		 2xkwB-3kmvA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3kmv ALPHA-L-ARABINOFURAN
OSIDASE B
(Ruminiclostridiu
m
thermocellum) 		3 / 3 GLY A  49
THR A  93
ASN A  52
 None
 0.64A 3v4tD-3kmvA:
undetectable		 3v4tD-3kmvA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3kmv ALPHA-L-ARABINOFURAN
OSIDASE B
(Ruminiclostridiu
m
thermocellum) 		4 / 5 ILE A 118
PHE A  28
SER A 110
ASP A  76
 None
FMT  A 162 (-3.8A)
None
CA  A 163 (-3.2A)
 1.42A 4rzvB-3kmvA:
undetectable		 4rzvB-3kmvA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_B_ACTB401_0
(3C-LIKE PROTEINASE)		 3kmv ALPHA-L-ARABINOFURAN
OSIDASE B
(Ruminiclostridiu
m
thermocellum) 		3 / 3 ARG A 126
ASP A 128
TYR A  75
 None
None
GOL  A 158 (-4.1A)
 0.96A 4yo9B-3kmvA:
undetectable		 4yo9B-3kmvA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 3kmv ALPHA-L-ARABINOFURAN
OSIDASE B
(Ruminiclostridiu
m
thermocellum) 		4 / 6 SER A  73
SER A  78
ALA A  92
SER A  91
 None
 1.02A 6bocA-3kmvA:
undetectable
6bocB-3kmvA:
undetectable
6bocC-3kmvA:
undetectable
6bocD-3kmvA:
undetectable		 6bocA-3kmvA:
11.92
6bocB-3kmvA:
11.92
6bocC-3kmvA:
11.92
6bocD-3kmvA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 3kmv ALPHA-L-ARABINOFURAN
OSIDASE B
(Ruminiclostridiu
m
thermocellum) 		4 / 6 SER A  91
SER A  73
SER A  78
ALA A  92
 None
 0.99A 6bocA-3kmvA:
undetectable
6bocB-3kmvA:
undetectable
6bocC-3kmvA:
undetectable
6bocD-3kmvA:
undetectable		 6bocA-3kmvA:
11.92
6bocB-3kmvA:
11.92
6bocC-3kmvA:
11.92
6bocD-3kmvA:
11.92