SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kn1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CRB_A_RTLA200_0
(CELLULAR RETINOL
BINDING PROTEIN)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 12 PHE A 253
LEU A 249
LEU A  69
ALA A 252
ILE A 240
 None
 0.92A 1crbA-3kn1A:
undetectable		 1crbA-3kn1A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		6 / 11 LEU A 133
ALA A 136
GLU A 135
LEU A 170
ARG A 176
LEU A  94
 None
 1.30A 1g50A-3kn1A:
undetectable		 1g50A-3kn1A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 11 LEU A 133
ALA A 136
LEU A 156
ILE A  95
LEU A 103
 None
 1.13A 1g50A-3kn1A:
undetectable		 1g50A-3kn1A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 10 LEU A 133
ALA A 136
GLU A 135
LEU A 170
LEU A  94
 None
 1.22A 1gwrA-3kn1A:
undetectable		 1gwrA-3kn1A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4H_A_REAA500_1
(NUCLEAR RECEPTOR
ROR-BETA)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 11 CYH A  92
ILE A  95
ALA A  98
VAL A 288
ALA A 295
 None
 1.15A 1n4hA-3kn1A:
undetectable		 1n4hA-3kn1A:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 10 LEU A 133
ALA A 136
GLU A 135
ARG A 176
LEU A  94
 None
 1.29A 1pcgA-3kn1A:
undetectable		 1pcgA-3kn1A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 10 LEU A 133
ALA A 136
GLU A 135
LEU A 170
LEU A  94
 None
 1.19A 1pcgA-3kn1A:
undetectable		 1pcgA-3kn1A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 10 LEU A 133
ALA A 136
LEU A 156
ILE A  95
LEU A 103
 None
 1.06A 1pcgA-3kn1A:
undetectable		 1pcgA-3kn1A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_B_ESTB2_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 10 LEU A 133
ALA A 136
GLU A 135
ARG A 176
LEU A  94
 None
 1.30A 1pcgB-3kn1A:
undetectable		 1pcgB-3kn1A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_B_ESTB2_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 10 LEU A 133
ALA A 136
GLU A 135
LEU A 170
LEU A  94
 None
 1.19A 1pcgB-3kn1A:
undetectable		 1pcgB-3kn1A:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_A_DESA459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 12 LEU A  62
ALA A 245
VAL A 268
LEU A 237
ILE A  95
 None
 1.15A 1s9pA-3kn1A:
undetectable		 1s9pA-3kn1A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 11 LEU A 170
LEU A 156
THR A 128
PRO A 127
LEU A 177
 None
 1.11A 2ft9A-3kn1A:
undetectable		 2ft9A-3kn1A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCF_A_ESTA596_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 10 LEU A 133
ALA A 136
GLU A 135
ARG A 176
LEU A  94
 None
 1.34A 2ocfA-3kn1A:
undetectable		 2ocfA-3kn1A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCF_A_ESTA596_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 10 LEU A 133
ALA A 136
GLU A 135
LEU A 170
LEU A  94
 None
 1.15A 2ocfA-3kn1A:
undetectable		 2ocfA-3kn1A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 12 THR A  61
LEU A  68
LEU A  69
ILE A  85
LEU A 177
 None
 1.14A 2qxsA-3kn1A:
undetectable		 2qxsA-3kn1A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_B_CHDB2_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		3 / 3 LEU A  68
LEU A  71
ARG A  74
 None
 0.75A 3hcnB-3kn1A:
undetectable		 3hcnB-3kn1A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 12 LEU A 133
ALA A 136
GLU A 135
LEU A 170
LEU A  94
 None
 1.14A 3hm1A-3kn1A:
undetectable		 3hm1A-3kn1A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_D_BCZD1001_0
(NEURAMINIDASE)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 12 GLU A  64
LEU A 181
ALA A 238
ARG A 235
ARG A 100
 None
None
None
SO4  A   4 (-4.5A)
SO4  A   3 (-4.5A)
 1.40A 3k39D-3kn1A:
undetectable		 3k39D-3kn1A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_N_BCZN1001_0
(NEURAMINIDASE)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 12 GLU A  64
LEU A 181
ALA A 238
ARG A 235
ARG A 100
 None
None
None
SO4  A   4 (-4.5A)
SO4  A   3 (-4.5A)
 1.39A 3k39N-3kn1A:
undetectable		 3k39N-3kn1A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_P_BCZP1001_0
(NEURAMINIDASE)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 12 GLU A  64
LEU A 181
ALA A 238
ARG A 235
ARG A 100
 None
None
None
SO4  A   4 (-4.5A)
SO4  A   3 (-4.5A)
 1.41A 3k39P-3kn1A:
undetectable		 3k39P-3kn1A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		6 / 12 LEU A 133
ALA A 136
GLU A 135
ARG A 176
GLY A  91
LEU A  94
 None
 1.35A 3olsA-3kn1A:
undetectable		 3olsA-3kn1A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		6 / 12 LEU A 133
ALA A 136
GLU A 135
LEU A 170
GLY A  91
LEU A  94
 None
 1.25A 3olsA-3kn1A:
undetectable		 3olsA-3kn1A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 12 LEU A 133
ALA A 136
GLU A 135
LEU A 170
LEU A  94
 None
 1.17A 3olsB-3kn1A:
undetectable		 3olsB-3kn1A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 12 LEU A 133
ALA A 136
LEU A 156
ILE A  95
LEU A 103
 None
 1.01A 3q95A-3kn1A:
undetectable		 3q95A-3kn1A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 12 LEU A 133
ALA A 136
LEU A 156
ILE A  95
LEU A 103
 None
 1.05A 3q95B-3kn1A:
undetectable		 3q95B-3kn1A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 12 LEU A 103
LEU A  94
ALA A 136
LEU A 133
LEU A  62
 None
 1.00A 3r9cA-3kn1A:
undetectable		 3r9cA-3kn1A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 11 LEU A 133
ALA A 136
GLU A 135
LEU A 170
LEU A  94
 None
 1.18A 3uudA-3kn1A:
undetectable		 3uudA-3kn1A:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6V_E_RBFE201_1
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		4 / 5 VAL A  66
GLU A  65
VAL A 217
LYS A 216
 None
 1.21A 4p6vB-3kn1A:
undetectable
4p6vE-3kn1A:
undetectable		 4p6vB-3kn1A:
18.42
4p6vE-3kn1A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 11 LEU A 133
ALA A 136
GLU A 135
ARG A 176
LEU A  94
 None
 1.34A 4zn7B-3kn1A:
undetectable		 4zn7B-3kn1A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 11 LEU A 133
ALA A 136
GLU A 135
LEU A 170
LEU A  94
 None
 1.23A 4zn7B-3kn1A:
undetectable		 4zn7B-3kn1A:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 10 LEU A 133
ALA A 136
GLU A 135
ARG A 176
LEU A  94
 None
 1.31A 5dxbA-3kn1A:
undetectable		 5dxbA-3kn1A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 10 LEU A 133
ALA A 136
GLU A 135
LEU A 170
LEU A  94
 None
 1.17A 5dxbA-3kn1A:
undetectable		 5dxbA-3kn1A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_B_ESTB1000_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 10 LEU A 133
ALA A 136
GLU A 135
ARG A 176
LEU A  94
 None
 1.30A 5dxeB-3kn1A:
undetectable		 5dxeB-3kn1A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_B_ESTB1000_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 10 LEU A 133
ALA A 136
GLU A 135
LEU A 170
LEU A  94
 None
 1.15A 5dxeB-3kn1A:
undetectable		 5dxeB-3kn1A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 10 LEU A 133
ALA A 136
GLU A 135
ARG A 176
LEU A  94
 None
 1.32A 5hyrA-3kn1A:
undetectable		 5hyrA-3kn1A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 10 LEU A 133
ALA A 136
GLU A 135
LEU A 170
LEU A  94
 None
 1.18A 5hyrA-3kn1A:
undetectable		 5hyrA-3kn1A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		5 / 12 PHE A 253
LEU A 249
LEU A  69
ALA A 252
ILE A 240
 None
 1.13A 5ljeA-3kn1A:
undetectable		 5ljeA-3kn1A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 3kn1 GOLGI PHOSPHOPROTEIN
3
(Homo
sapiens) 		4 / 8 ALA A 252
GLY A  70
LEU A  69
ALA A 243
 None
 0.78A 6mdqA-3kn1A:
undetectable		 6mdqA-3kn1A:
15.54