SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kn3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3kn3 PUTATIVE PERIPLASMIC
PROTEIN
(Wolinella
succinogenes) 		4 / 6 SER A  11
THR A  12
PHE A  83
GLY A 122
 GOL  A 262 ( 4.1A)
None
None
GOL  A 262 (-4.1A)
 0.96A 1icuA-3kn3A:
undetectable
1icuB-3kn3A:
undetectable		 1icuA-3kn3A:
21.45
1icuB-3kn3A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_D_NIOD223_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3kn3 PUTATIVE PERIPLASMIC
PROTEIN
(Wolinella
succinogenes) 		4 / 5 PHE A  83
GLY A 122
SER A  11
THR A  12
 None
GOL  A 262 (-4.1A)
GOL  A 262 ( 4.1A)
None
 0.94A 1icuC-3kn3A:
undetectable
1icuD-3kn3A:
undetectable		 1icuC-3kn3A:
21.45
1icuD-3kn3A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3kn3 PUTATIVE PERIPLASMIC
PROTEIN
(Wolinella
succinogenes) 		4 / 6 SER A  11
THR A  12
PHE A  83
GLY A 122
 GOL  A 262 ( 4.1A)
None
None
GOL  A 262 (-4.1A)
 1.01A 1kqbA-3kn3A:
undetectable
1kqbB-3kn3A:
undetectable		 1kqbA-3kn3A:
20.25
1kqbB-3kn3A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3kn3 PUTATIVE PERIPLASMIC
PROTEIN
(Wolinella
succinogenes) 		4 / 6 SER A  11
THR A  12
PHE A  83
GLY A 122
 GOL  A 262 ( 4.1A)
None
None
GOL  A 262 (-4.1A)
 1.01A 1kqbC-3kn3A:
undetectable
1kqbD-3kn3A:
undetectable		 1kqbC-3kn3A:
20.25
1kqbD-3kn3A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3kn3 PUTATIVE PERIPLASMIC
PROTEIN
(Wolinella
succinogenes) 		4 / 6 PHE A  83
GLY A 122
SER A  11
THR A  12
 None
GOL  A 262 (-4.1A)
GOL  A 262 ( 4.1A)
None
 0.99A 1kqbC-3kn3A:
undetectable
1kqbD-3kn3A:
undetectable		 1kqbC-3kn3A:
20.25
1kqbD-3kn3A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3kn3 PUTATIVE PERIPLASMIC
PROTEIN
(Wolinella
succinogenes) 		4 / 7 MET A  79
GLN A 231
ALA A 235
GLU A 228
 None
 1.32A 1t9wA-3kn3A:
undetectable		 1t9wA-3kn3A:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 3kn3 PUTATIVE PERIPLASMIC
PROTEIN
(Wolinella
succinogenes) 		4 / 6 ASN A 198
ASN A  81
ILE A 174
THR A 123
 None
None
None
GOL  A 262 (-4.0A)
 1.21A 2hkkA-3kn3A:
undetectable		 2hkkA-3kn3A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 3kn3 PUTATIVE PERIPLASMIC
PROTEIN
(Wolinella
succinogenes) 		3 / 3 PHE A 173
VAL A  84
GLU A 191
 None
 0.81A 4fvqA-3kn3A:
undetectable		 4fvqA-3kn3A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 3kn3 PUTATIVE PERIPLASMIC
PROTEIN
(Wolinella
succinogenes) 		4 / 7 ILE A  85
PHE A 104
LEU A 196
ASP A 193
 None
 1.08A 4mmcA-3kn3A:
undetectable		 4mmcA-3kn3A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 3kn3 PUTATIVE PERIPLASMIC
PROTEIN
(Wolinella
succinogenes) 		3 / 3 MET A  98
GLU A 102
LEU A 106
 None
 0.68A 4v2oB-3kn3A:
undetectable		 4v2oB-3kn3A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_A_ACTA701_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3kn3 PUTATIVE PERIPLASMIC
PROTEIN
(Wolinella
succinogenes) 		3 / 3 LYS A  61
LYS A 126
SER A 125
 None
 1.09A 5odiA-3kn3A:
undetectable		 5odiA-3kn3A:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLO_A_GBQA1501_1
(SUBSTANCE-P
RECEPTOR,GLGA
GLYCOGEN
SYNTHASE,SUBSTANCE-P
RECEPTOR)		 3kn3 PUTATIVE PERIPLASMIC
PROTEIN
(Wolinella
succinogenes) 		5 / 9 ILE A 225
ILE A 222
GLN A 231
VAL A  78
ILE A 202
 None
 1.28A 6hloA-3kn3A:
undetectable		 6hloA-3kn3A:
19.53