SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3knb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 3knb OBSCURIN-LIKE
PROTEIN 1
(Homo
sapiens) 		3 / 3 CYH B  35
PHE B  19
PHE B  16
 None
 0.82A 3cr5X-3knbB:
undetectable		 3cr5X-3knbB:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)		 3knb OBSCURIN-LIKE
PROTEIN 1
(Homo
sapiens) 		5 / 9 VAL B  45
VAL B  44
GLU B  94
GLY B  39
ALA B  67
 None
 1.18A 4fwdA-3knbB:
undetectable		 4fwdA-3knbB:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3knb OBSCURIN-LIKE
PROTEIN 1
(Homo
sapiens) 		4 / 8 LEU B  73
VAL B  23
VAL B 103
LEU B  71
 None
 0.77A 4puoC-3knbB:
undetectable		 4puoC-3knbB:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3knb OBSCURIN-LIKE
PROTEIN 1
(Homo
sapiens) 		4 / 8 LEU B  73
VAL B  23
VAL B 103
LEU B  71
 None
 0.83A 4q0bA-3knbB:
undetectable		 4q0bA-3knbB:
12.29