SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3kny'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_2
(ANGIOTENSIN
CONVERTING ENZYME)		 3kny HYPOTHETICAL PROTEIN
BT_3535
(Bacteroides
thetaiotaomicron) 		4 / 4 SER A 210
VAL A  26
PHE A 190
VAL A 177
 None
 1.34A 1o86A-3knyA:
undetectable		 1o86A-3knyA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3kny HYPOTHETICAL PROTEIN
BT_3535
(Bacteroides
thetaiotaomicron) 		4 / 7 SER A 194
CYH A 209
ILE A 157
SER A 175
 None
 1.23A 2xz5A-3knyA:
undetectable
2xz5B-3knyA:
undetectable		 2xz5A-3knyA:
23.14
2xz5B-3knyA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 3kny HYPOTHETICAL PROTEIN
BT_3535
(Bacteroides
thetaiotaomicron) 		4 / 5 ILE A  95
ILE A  71
TYR A  69
GLU A  70
 None
 1.18A 4a99D-3knyA:
undetectable		 4a99D-3knyA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3kny HYPOTHETICAL PROTEIN
BT_3535
(Bacteroides
thetaiotaomicron) 		4 / 6 THR A  64
LEU A 204
ASN A  94
GLU A  87
 None
 1.15A 4nc3A-3knyA:
undetectable		 4nc3A-3knyA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3kny HYPOTHETICAL PROTEIN
BT_3535
(Bacteroides
thetaiotaomicron) 		3 / 3 TYR A 141
THR A 143
THR A 119
 None
 0.70A 5aoxB-3knyA:
undetectable		 5aoxB-3knyA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3kny HYPOTHETICAL PROTEIN
BT_3535
(Bacteroides
thetaiotaomicron) 		3 / 3 TYR A 141
THR A 143
THR A 119
 None
 0.77A 5aoxE-3knyA:
undetectable		 5aoxE-3knyA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 3kny HYPOTHETICAL PROTEIN
BT_3535
(Bacteroides
thetaiotaomicron) 		4 / 6 LYS A 158
TYR A 156
PRO A 188
LEU A 213
 None
 1.22A 5bmvB-3knyA:
undetectable		 5bmvB-3knyA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 3kny HYPOTHETICAL PROTEIN
BT_3535
(Bacteroides
thetaiotaomicron) 		4 / 7 THR A  64
LEU A 204
ASN A  94
GLU A  87
 None
 1.06A 5tudA-3knyA:
undetectable		 5tudA-3knyA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kny HYPOTHETICAL PROTEIN
BT_3535
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A  69
ARG A  68
MET A  65
THR A  64
 None
 1.32A 5x19J-3knyA:
undetectable		 5x19J-3knyA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kny HYPOTHETICAL PROTEIN
BT_3535
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A  69
ARG A  68
MET A  65
THR A  64
 None
 1.38A 5x1bJ-3knyA:
undetectable		 5x1bJ-3knyA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kny HYPOTHETICAL PROTEIN
BT_3535
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A  69
ARG A  68
MET A  65
THR A  64
 None
 1.13A 5x1bW-3knyA:
undetectable		 5x1bW-3knyA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3kny HYPOTHETICAL PROTEIN
BT_3535
(Bacteroides
thetaiotaomicron) 		4 / 5 TYR A  69
ARG A  68
MET A  65
THR A  64
 None
 1.13A 6nknJ-3knyA:
undetectable		 6nknJ-3knyA:
17.65